Abstract 3212: ONC201 shows efficacy in BRCA-deficient cancer cells and synergy with PARP inhibitors in glioblastoma, breast, prostate, and ovarian cancers von Baumeister, Marie D., Küçükkase, Ozan C., Prabhu, Varun V., Dicker, David T., Allen, Josh E., El-Deiry, Wafik S.

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Abstract 3309: Novel small molecule ONC201 induces cell death and targets chemotherapy-resistant cancer stem-like cells in triple negative breast cancer von Baumeister, Marie D., Wagner, Jessica, Prabhu, Varun V., Kline, Christina LB, Lim, Bora, Allen, Josh E., Dicker, David T., El-Deiry, Wafik S.

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Abstract 3012: ONC201 induces cell death in triple negative, BRCA1-deficient and non-triple negative breast cancer cells von Baumeister, Marie D., Wagner, Jessica, Prabhu, Varun V., Kline, Christina LB, Lim, Bora, Allen, Josh E., Dicker, David T., El-Deiry, Wafik S.

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Abstract 349: Structure-activity relationships and mechanistic analysis of analogues of the clinical-stage anti-cancer small molecule ONC201 von Wagner, Jessica, Olson, Gary, Bhaskara, Nallaganchu Rao, Pottorf, Richard S., Mathew, Garnett J., Benes, Cyril H., Tarapore, Rohinton, Stogniew, Martin, Schalop, Lee, Oster, Wolfgang, Allen, Josh E., El-Deiry, Wafik S.

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Social networks strongly predict the gut microbiota of wild mice von Raulo, Aura, Allen, Bryony E., Troitsky, Tanya, Husby, Arild, Firth, Josh A., Coulson, Tim, Knowles, Sarah C. L.

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Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression von Allen, Josh, Romay-Tallon, Raquel, Brymer, Kyle J, Caruncho, Hector J, Kalynchuk, Lisa E

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Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation von Montgomery, Taiowa A., Howell, Miya D., Cuperus, Josh T., Li, Dawei, Hansen, Jesse E., Alexander, Amanda L., Chapman, Elisabeth J., Fahlgren, Noah, Allen, Edwards, Carrington, James C.

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Diatom centromeres suggest a mechanism for nuclear DNA acquisition von Diner, Rachel E., Noddings, Chari M., Lian, Nathan C., Kang, Anthony K., McQuaid, Jeffrey B., Jablanovic, Jelena, Espinoza, Josh L., Nguyen, Ngocquynh A., Anzelmatti, Miguel A., Jansson, Jakob, Bielinski, Vincent A., Karas, Bogumil J., Dupont, Christopher L., Allen, Andrew E., Weyman, Philip D.

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Fast-acting antidepressant-like effects of Reelin evaluated in the repeated-corticosterone chronic stress paradigm von Brymer, Kyle J, Johnston, Jenessa, Botterill, Justin J, Romay-Tallon, Raquel, Mitchell, Milann A, Allen, Josh, Pinna, Graziano, Caruncho, Hector J, Kalynchuk, Lisa E

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Severe life stress, mitochondrial dysfunction, and depressive behavior: A pathophysiological and therapeutic perspective von Allen, Josh, Caruncho, Hector J., Kalynchuk, Lisa E.

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An impact evaluation of conservation investments targeting long‐distance migratory species von Donlan, C. Josh, Eusse‐González, Diana, Luque, Gloria M., Reiter, Matthew E., Ruiz‐Gutierrez, Viviana, Allen, Michael C., Johnston‐González, Richard, Robinson, Orin J., Fernández, Guillermo, Palacios, Eduardo, Valenzuela, Jorge

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Exploring the Potential Antidepressant Mechanisms of TNFα Antagonists von Brymer, Kyle J, Romay-Tallon, Raquel, Allen, Josh, Caruncho, Hector J, Kalynchuk, Lisa E

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A validated model for the 22‐item Sino‐Nasal Outcome Test subdomain structure in chronic rhinosinusitis von Feng, Allen L., Wesely, Nicholas C., Hoehle, Lloyd P., Phillips, Katie M., Yamasaki, Alisa, Campbell, Adam P., Gregorio, Luciano L., Killeen, Thomas E., Caradonna, David S., Meier, Josh C., Gray, Stacey T., Sedaghat, Ahmad R.

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Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing von Allen, William E., Altae-Tran, Han, Briggs, James, Jin, Xin, McGee, Glen, Shi, Andy, Raghavan, Rumya, Kamariza, Mireille, Nova, Nicole, Pereta, Albert, Danford, Chris, Kamel, Amine, Gothe, Patrik, Milam, Evrhet, Aurambault, Jean, Primke, Thorben, Li, Weijie, Inkenbrandt, Josh, Huynh, Tuan, Chen, Evan, Lee, Christina, Croatto, Michael, Bentley, Helen, Lu, Wendy, Murray, Robert, Travassos, Mark, Coull, Brent A., Openshaw, John, Greene, Casey S., Shalem, Ophir, King, Gary, Probasco, Ryan, Cheng, David R., Silbermann, Ben, Zhang, Feng, Lin, Xihong

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CSER and eMERGE: current and potential state of the display of genetic information in the electronic health record von Shirts, Brian H, Salama, Joseph S, Aronson, Samuel J, Chung, Wendy K, Gray, Stacy W, Hindorff, Lucia A, Jarvik, Gail P, Plon, Sharon E, Stoffel, Elena M, Tarczy-Hornoch, Peter Z, Van Allen, Eliezer M, Weck, Karen E, Chute, Christopher G, Freimuth, Robert R, Grundmeier, Robert W, Hartzler, Andrea L, Li, Rongling, Peissig, Peggy L, Peterson, Josh F, Rasmussen, Luke V, Starren, Justin B, Williams, Marc S, Overby, Casey L

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Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration von Chen, Wei, Stambolian, Dwight, Edwards, Albert O, Branham, Kari E, Othman, Mohammad, Jakobsdottir, Johanna, Tosakulwong, Nirubol, Pericak-Vance, Margaret A, Campochiaro, Peter A, Klein, Michael L, Tan, Perciliz L, Conley, Yvette P, Kanda, Atsuhiro, Kopplin, Laura, Li, Yanming, Augustaitis, Katherine J, Karoukis, Athanasios J, Scott, William K, Agarwal, Anita, Kovach, Jaclyn L, Schwartz, Stephen G, Postel, Eric A, Brooks, Matthew, Baratz, Keith H, Brown, William L, Brucker, Alexander J, Orlin, Anton, Brown, Gary, Ho, Allen, Regillo, Carl, Donoso, Larry, Tian, Lifeng, Kaderli, Brian, Hadley, Dexter, Hagstrom, Stephanie A, Peachey, Neal S, Klein, Ronald, Klein, Barbara E.K, Gotoh, Norimoto, Yamashiro, Kenji, Ferris III, Frederick, Fagerness, Jesen A, Reynolds, Robyn, Farrer, Lindsay A, Kim, Ivana K, Miller, Joan W, Cortón, Marta, Carracedo, Angel, Sanchez-Salorio, Manuel, Pugh, Elizabeth W, Doheny, Kimberly F, Brion, Maria, DeAngelis, Margaret M, Weeks, Daniel E, Zack, Donald J, Chew, Emily Y, Heckenlively, John R, Yoshimura, Nagahisa, Iyengar, Sudha K, Francis, Peter J, Katsanis, Nicholas, Seddon, Johanna M, Haines, Jonathan L, Gorin, Michael B, Abecasis, Gonçalo R, Swaroop, Anand

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MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer von Nickols, Nicholas G., Nazarian, Ramin, Zhao, Shuang G., Tan, Victor, Uzunangelov, Vladislav, Xia, Zheng, Baertsch, Robert, Neeman, Elad, Gao, Allen C., Thomas, George V., Howard, Lauren, De Hoedt, Amanda M., Stuart, Josh, Goldstein, Theodore, Chi, Kim, Gleave, Martin E., Graff, Julie N., Beer, Tomasz M., Drake, Justin M., Evans, Christopher P., Aggarwal, Rahul, Foye, Adam, Feng, Felix Y., Small, Eric J., Aronson, William J., Freedland, Stephen J., Witte, Owen N., Huang, Jiaoti, Alumkal, Joshi J., Reiter, Robert E., Rettig, Matthew B.

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Non-Fusion Versus Fusion Surgery in Pediatric Idiopathic Scoliosis: What Trade-Offs in Outcomes Are Acceptable for the Patient and Family? von Larson, A Noelle, Marks, Michelle Claire, Gonzalez Sepulveda, Juan Marcos, Newton, Peter O, Devlin, Vincent J, Peat, Raquel, Tarver, Michelle E, Babalola, Olufemi, Chen, Allen L, Gebben, David, Cahill, Patrick, Shah, Suken, Samdani, Amer, Bachmann, Keith, Lonner, Baron

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Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress releva... von Lebedeva, Katherina A., Allen, Josh, Kulhawy, Erin Y., Caruncho, Hector J., Kalynchuk, Lisa E.

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Mechanical indications for inflatable penile prosthesis revision: analysis and implications for revision surgery von Smelser, Ashton M, VanDyke, Maia E, Nealon, Samantha W, Badkhshan, Shervin, Langford, Brian T, Peedikayil, Josh, El-Eishy, Al-Frooq, Monaghan, Thomas F, Sanders, Sarah C, Franzen, Bryce P, Morey, Allen F

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