A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression von Auciello, Francesca R, Bulusu, Vinay, Oon, Chet, Tait-Mulder, Jacqueline, Berry, Mark, Bhattacharyya, Sohinee, Tumanov, Sergey, Allen-Petersen, Brittany L, Link, Jason, Kendsersky, Nicholas D, Vringer, Esmee, Schug, Michelle, Novo, David, Hwang, Rosa F, Evans, Ronald M, Nixon, Colin, Dorrell, Craig, Morton, Jennifer P, Norman, Jim C, Sears, Rosalie C, Kamphorst, Jurre J, Sherman, Mara H

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer von Janghorban, Mahnaz, Farrell, Amy S., Allen-Petersen, Brittany L., Pelz, Carl, Daniel, Colin J., Oddo, Jessica, Langer, Ellen M., Christensen, Dale J., Sears, Rosalie C.

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Maternal mRNAs are regulated by diverse P body-related mRNP granules during early Caenorhabditis elegans development von Noble, Scott L, Allen, Brittany L, Goh, Lai Kuan, Nordick, Kristen, Evans, Thomas C

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Microfluidics Formulated Liposomes of Hypoxia Activated Prodrug for Treatment of Pancreatic Cancer von Shah, Vidhi M, Dorrell, Craig, Al-Fatease, Adel, Allen-Petersen, Brittany L, Woo, Yeonhee, Bortnyak, Yuliya, Gheewala, Rohi, Sheppard, Brett C, Sears, Rosalie C, Alani, Adam Wg

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Sendai virus is robust and consistent in delivering genes into human pancreatic cancer cells von Grygoryev, Dmytro, Ekstrom, Taelor, Manalo, Elise, Link, Jason M., Alshaikh, Amani, Keith, Dove, Allen-Petersen, Brittany L., Sheppard, Brett, Morgan, Terry, Soufi, Abdenour, Sears, Rosalie C., Kim, Jungsun

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Mission Possible: Advances in MYC Therapeutic Targeting in Cancer von Allen-Petersen, Brittany L., Sears, Rosalie C.

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Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting von Langer, Ellen M., Allen-Petersen, Brittany L., King, Shelby M., Kendsersky, Nicholas D., Turnidge, Megan A., Kuziel, Genevra M., Riggers, Rachelle, Samatham, Ravi, Amery, Taylor S., Jacques, Steven L., Sheppard, Brett C., Korkola, James E., Muschler, John L., Thibault, Guillaume, Chang, Young Hwan, Gray, Joe W., Presnell, Sharon C., Nguyen, Deborah G., Sears, Rosalie C.

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Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers von Farrington, Caroline C., Yuan, Eric, Mazhar, Sahar, Izadmehr, Sudeh, Hurst, Lauren, Allen-Petersen, Brittany L., Janghorban, Mahnaz, Chung, Eric, Wolczanski, Grace, Galsky, Matthew, Sears, Rosalie, Sangodkar, Jaya, Narla, Goutham

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Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma von Allen-Petersen, Brittany L, Risom, Tyler, Feng, Zipei, Wang, Zhiping, Jenny, Zina P, Thoma, Mary C, Pelz, Katherine R, Morton, Jennifer P, Sansom, Owen J, Lopez, Charles D, Sheppard, Brett, Christensen, Dale J, Ohlmeyer, Michael, Narla, Goutham, Sears, Rosalie C

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PP2A and cancer epigenetics: a therapeutic opportunity waiting to happen von Tinsley, Samantha L, Allen-Petersen, Brittany L

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KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development von Tinsley, Samantha L., Chianis, Ella Rose D., Shelley, Rebecca A., Mall, Gaganpreet K., Dhiman, Alisha, Baral, Garima, Kothandaraman, Harish, Thoma, Mary C., English, Isabel A., Daniel, Colin J., Acosta, Luis Carlos Sanjuan, Solorio, Luis, Atallah Lanman, Nadia, Pasca di Magliano, Marina, Narla, Goutham, Dykhuizen, Emily C., Sears, Rosalie C., Allen-Petersen, Brittany L.

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The use of protein phosphatase 2A activators in combination therapies for pancreas cancer von Allen-Petersen, Brittany L, Sears, Rosalie C

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Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers von Farrington, Caroline C., Yuan, Eric, Mazhar, Sahar, Izadmehr, Sudeh, Hurst, Lauren, Allen-Petersen, Brittany L., Janghorban, Mahnaz, Chung, Eric, Wolczanski, Grace, Galsky, Matthew, Sears, Rosalie, Sangodkar, Jaya, Narla, Goutham

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Sustained degradation of hyaluronic acid using an in situ forming implant von Hopkins, Kelsey, Buno, Kevin, Romick, Natalie, Freitas Dos Santos, Antonio Carlos, Tinsley, Samantha, Wakelin, Elizabeth, Kennedy, Jacqueline, Ladisch, Michael, Allen-Petersen, Brittany L, Solorio, Luis

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In vivo inhibition of angiogenesis by interleukin‐13 gene therapy in a rat model of rheumatoid arthritis von Haas, Christian S., Amin, M. Asif, Ruth, Jeffrey H., Allen, Brittany L., Ahmed, Salahuddin, Pakozdi, Angela, Woods, James M., Shahrara, Shiva, Koch, Alisa E.

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Abstract IA-06: Heterotypic 3D bioprinted tissues to study pancreatic cancer von Langer, Ellen M, Allen-Petersen, Brittany L, English, Isabel A, Link, Jason M, Sears, Rosalie C

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Unbiased discovery of cancer pathways and therapeutics using Pathway Ensemble Tool and Benchmark von Wang, Luopin, Pattnaik, Aryamav, Sahoo, Subhransu Sekhar, Stone, Ella G., Zhuang, Yuxin, Benton, Annaleigh, Tajmul, Md, Chakravorty, Srishti, Dhawan, Deepika, Nguyen, My An, Sirit, Isabella, Mundy, Kyle, Ricketts, Christopher J., Hadisurya, Marco, Baral, Garima, Tinsley, Samantha L., Anderson, Nicole L., Hoda, Smriti, Briggs, Scott D., Kaimakliotis, Hristos Z., Allen-Petersen, Brittany L., Tao, W. Andy, Linehan, W. Marston, Knapp, Deborah W., Hanna, Jason A., Olson, Matthew R., Afzali, Behdad, Kazemian, Majid

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Abstract PO-113: The prolyl isomerase PIN1 plays a critical role in fibroblast differentiation states to support pancreatic cancer von Langer, Ellen M., English, Isabel A., Shah, Vidhi, MacPherson, Kevin, Kresse, Kayleigh M., Allen-Petersen, Brittany L., Daniel, Colin J., Sherman, Mara H., Adey, Andrew, Sears, Rosalie C.

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Abstract LT012: The prolyl isomerase PIN1 plays a critical role in fibroblast plasticity to impact pancreatic cancer von Langer, Ellen M., English, Isabel A., Kresse, Kayleigh M., MacPherson, Kevin, Allen-Petersen, Brittany L., Daniel, Colin J., Adey, Andrew, Sears, Rosalie C.

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MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance von Farrell, Amy S., Joly, Meghan Morrison, Allen-Petersen, Brittany L., Worth, Patrick J., Lanciault, Christian, Sauer, David, Link, Jason, Pelz, Carl, Heiser, Laura M., Morton, Jennifer P., Muthalagu, Nathiya, Hoffman, Megan T., Manning, Sara L., Pratt, Erica D., Kendsersky, Nicholas D., Egbukichi, Nkolika, Amery, Taylor S., Thoma, Mary C., Jenny, Zina P., Rhim, Andrew D., Murphy, Daniel J., Sansom, Owen J., Crawford, Howard C., Sheppard, Brett C., Sears, Rosalie C.

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