Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors von Rosenthal, E.L., Chung, T.K., Parker, W.B., Allan, P.W., Clemons, L., Lowman, D., Hong, J., Hunt, F.R., Richman, J., Conry, R.M., Mannion, K., Carroll, W.R., Nabell, L., Sorscher, E.J.

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Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells von Parker, William B, Allan, Paula W, Shaddix, Sue C, Rose, Lucy M, Speegle, Heath F, Gillespie, G.Yancey, Bennett, L.Lee

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Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase von Parker, W B, Allan, P W, Waud, W R, Hong, J S, Sorscher, E J

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Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase von Bennett, Eric M., Li, Chenglong, Allan, Paula W., Parker, William B., Ealick, Steven E.

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Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells von RITKE, M. K, ROBERTS, D, ALLAN, W. P, RAYMOND, J, BERGOLTZ, V. V, YALOWICH, J. C

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Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II von Hasinoff, Brian B., Kuschak, Theodore I., Creighton, Andrew M., Fattman, Cheryl L., Allan, William P., Thampatty, Padmakumari, Yalowich, Jack C.

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Toxicity of Cordycepin in Combination with the Adenosine Deaminase Inhibitor 2′-Deoxycoformycin in Beagle Dogs von Rodman, Larry E., Farnell, Daniel R., Coyne, John M., Allan, Paula W., Hill, Donald L., Duncan, Kimberly L.K., Tomaszewski, Joseph E., Smith, Adaline C., Page, John G.

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Collateral sensitivity to the bisdioxopiperazine dexrazoxane (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells von Fattman, Cheryl L., Allan, William P., Hasinoff, Brian B., Yalowich, Jack C.

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Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells von Ritke, M K, Rusnak, J M, Lazo, J S, Allan, W P, Dive, C, Heer, S, Yalowich, J C

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The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines von Kurz, E U, Wilson, S E, Leader, K B, Sampey, B P, Allan, W P, Yalowich, J C, Kroll, D J

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Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase von Parker, William B, Allan, Paula W, Hassan, Abdalla E A, Secrist, 3rd, John A, Sorscher, Eric J, Waud, William R

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Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells von Ritke, M K, Allan, W P, Fattman, C, Gunduz, N N, Yalowich, J C

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Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: Substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kina... von BENNETT, L. L, ALLAN, P. W, ARNETT, G, SHEALY, Y. F, SHEWACH, D. S, MASON, W. S, FOUREL, I, PARKER, W. B

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The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells von Hasinoff, B B, Abram, M E, Barnabé, N, Khélifa, T, Allan, W P, Yalowich, J C

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Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy von BHARARA, Suman, SORSCHER, Eric J, PARKER, William B, WAUD, William R, GILLESPIE, G. Yancey, LINDSEY, J. Russell, HONG, Jeong S, CURLEE, Kimberly V, ALLAN, Paula W, GADI, V. K, ALEXANDER, Sherrie A, SECRIST, John A

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Increased c- jun/AP-1 levels in etoposide-resistant human leukemia K562 cells von Ritke, Mary K., Bergoltz, Vladimir V., Allan, William P., Yalowich, Jack C.

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Cell to Cell Contact Is Not Required for Bystander Cell Killing by Escherichia coli Purine Nucleoside Phosphorylase von Hughes, Brian W., King, Scott A., Allan, Paula W., Parker, William B., Sorscher, Eric J.

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Phosphorylation of the enantiomers of the carbocyclic analog of 2'-deoxyguanosine in cells infected with herpes simplex virus type 1 and in uninfected cells. Lack of enantiomeric s... von L L Bennett, Jr, W B Parker, P W Allan, L M Rose, Y F Shealy, J A Secrist, 3rd, J A Montgomery, G Arnett, R L Kirkman, W M Shannon

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In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase von Parker, W B, King, S A, Allan, P W, Bennett, Jr, L L, Secrist, 3rd, J A, Montgomery, J A, Gilbert, K S, Waud, W R, Wells, A H, Gillespie, G Y, Sorscher, E J

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Chemical synthesis and biological activity of a novel fluorescent etoposide derivative von Lazo, John S., Li, Tianhu, Woo, Elizabeth S., Settineri, Catherine E., Allan, William P., Yalowich, Jack C.

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