Current Bioinformatics Tools to Optimize CRISPR/Cas9 Experiments to Reduce Off-Target Effects von Naeem, Muhammad, Alkhnbashi, Omer S

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SpacerPlacer: ancestral reconstruction of CRISPR arrays reveals the evolutionary dynamics of spacer deletions von Fehrenbach, Axel, Mitrofanov, Alexander, Alkhnbashi, Omer S, Backofen, Rolf, Baumdicker, Franz

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Gene Expression-Based Cancer Classification for Handling the Class Imbalance Problem and Curse of Dimensionality von Al-Azani, Sadam, Alkhnbashi, Omer S, Ramadan, Emad, Alfarraj, Motaz

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Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation von Wimmer, Franziska, Englert, Frank, Wandera, Katharina G, Alkhnbashi, Omer S, Collins, Scott P, Backofen, Rolf, Beisel, Chase L

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Freiburg RNA tools: a central online resource for RNA-focused research and teaching von Raden, Martin, Ali, Syed M, Alkhnbashi, Omer S, Busch, Anke, Costa, Fabrizio, Davis, Jason A, Eggenhofer, Florian, Gelhausen, Rick, Georg, Jens, Heyne, Steffen, Hiller, Michael, Kundu, Kousik, Kleinkauf, Robert, Lott, Steffen C, Mohamed, Mostafa M, Mattheis, Alexander, Miladi, Milad, Richter, Andreas S, Will, Sebastian, Wolff, Joachim, Wright, Patrick R, Backofen, Rolf

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CRISPRstrand: predicting repeat orientations to determine the crRNA-encoding strand at CRISPR loci von Alkhnbashi, Omer S, Costa, Fabrizio, Shah, Shiraz A, Garrett, Roger A, Saunders, Sita J, Backofen, Rolf

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Education in Transition: Adapting and Thriving in a Post-COVID World von Alkhnbashi, Omer S, Mohammad, Rasheed, Bamasoud, Doaa M

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CdrS Is a Global Transcriptional Regulator Influencing Cell Division in Haloferax volcanii von Liao, Yan, Vogel, Verena, Hauber, Sabine, Bartel, Juergen, Alkhnbashi, Omer S., Maass, Sandra, Schwarz, Thandi S., Backofen, Rolf, Becher, Doerte, Duggin, Iain G., Marchfelder, Anita

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Structural constraints and enzymatic promiscuity in the Cas6-dependent generation of crRNAs von Reimann, Viktoria, Alkhnbashi, Omer S, Saunders, Sita J, Scholz, Ingeborg, Hein, Stephanie, Backofen, Rolf, Hess, Wolfgang R

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The role of Cas8 in type I CRISPR interference von Cass, Simon D B, Haas, Karina A, Stoll, Britta, Alkhnbashi, Omer S, Sharma, Kundan, Urlaub, Henning, Backofen, Rolf, Marchfelder, Anita, Bolt, Edward L

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Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants von Makarova, Kira S., Wolf, Yuri I., Iranzo, Jaime, Shmakov, Sergey A., Alkhnbashi, Omer S., Brouns, Stan J. J., Charpentier, Emmanuelle, Cheng, David, Haft, Daniel H., Horvath, Philippe, Moineau, Sylvain, Mojica, Francisco J. M., Scott, David, Shah, Shiraz A., Siksnys, Virginijus, Terns, Michael P., Venclovas, Česlovas, White, Malcolm F., Yakunin, Alexander F., Yan, Winston, Zhang, Feng, Garrett, Roger A., Backofen, Rolf, van der Oost, John, Barrangou, Rodolphe, Koonin, Eugene V.

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CRISPR-Cas bioinformatics von Alkhnbashi, Omer S., Meier, Tobias, Mitrofanov, Alexander, Backofen, Rolf, Voß, Björn

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An updated evolutionary classification of CRISPR–Cas systems von Makarova, Kira S., Wolf, Yuri I., Alkhnbashi, Omer S., Costa, Fabrizio, Shah, Shiraz A., Saunders, Sita J., Barrangou, Rodolphe, Brouns, Stan J. J., Charpentier, Emmanuelle, Haft, Daniel H., Horvath, Philippe, Moineau, Sylvain, Mojica, Francisco J. M., Terns, Rebecca M., Terns, Michael P., White, Malcolm F., Yakunin, Alexander F., Garrett, Roger A., van der Oost, John, Backofen, Rolf, Koonin, Eugene V.

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CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems von Lange, Sita J, Alkhnbashi, Omer S, Rose, Dominic, Will, Sebastian, Backofen, Rolf

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CRISPRtracrRNA: robust approach for CRISPR tracrRNA detection von Mitrofanov, Alexander, Ziemann, Marcus, Alkhnbashi, Omer S, Hess, Wolfgang R, Backofen, Rolf

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CRISPRidentify: identification of CRISPR arrays using machine learning approach von Mitrofanov, Alexander, Alkhnbashi, Omer S, Shmakov, Sergey A, Makarova, Kira S, Koonin, Eugene V, Backofen, Rolf

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Deepdefense: annotation of immune systems in prokaryotes using deep learning von Hauns, Sven, Alkhnbashi, Omer S, Backofen, Rolf

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Characterizing leader sequences of CRISPR loci von Alkhnbashi, Omer S, Shah, Shiraz A, Garrett, Roger A, Saunders, Sita J, Costa, Fabrizio, Backofen, Rolf

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An Integrated Multimodal-Based CAD System for Breast Cancer Diagnosis von Sunba, Amal, AlShammari, Maha, Almuhanna, Afnan, Alkhnbashi, Omer S.

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Anti-CRISPR prediction using deep learning reveals an inhibitor of Cas13b nucleases von Wandera, Katharina G, Alkhnbashi, Omer S, Bassett, Harris V I, Mitrofanov, Alexander, Hauns, Sven, Migur, Anzhela, Backofen, Rolf, Beisel, Chase L

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