A PROSS-designed extensively mutated estrogen receptor α variant displays enhanced thermal stability while retaining native allosteric regulation and structure von Kriegel, Mark, Wiederanders, Hanna J., Alkhashrom, Sewar, Eichler, Jutta, Muller, Yves A.

Volltext

A Peptide Inhibitor of the Human Cytomegalovirus Core Nuclear Egress Complex von Alkhashrom, Sewar, Kicuntod, Jintawee, Stillger, Katharina, Lützenburg, Tamara, Anzenhofer, Christian, Neundorf, Ines, Marschall, Manfred, Eichler, Jutta

Volltext

Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors von Alkhashrom, Sewar, Kicuntod, Jintawee, Haege, Sigrun, Schweininger, Johannes, Muller, Yves A., Lischka, Peter, Marschall, Manfred, Eichler, Jutta

Volltext

Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties von Marschall, Manfred, Haege, Sigrun, Conrad, Marcus, Alkhashrom, Sewar, Kicuntod, Jintawee, Schweininger, Johannes, Kriegel, Mark, Loesing, Josephine, Tillmanns, Julia, Neipel, Frank, Eichler, Jutta, Muller, Yves A., Sticht, Heinrich

Volltext

A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro von Aillaud, Isabelle, Kaniyappan, Senthilvelrajan, Chandupatla, Ram Reddy, Ramirez, Lisa Marie, Alkhashrom, Sewar, Eichler, Jutta, Horn, Anselm H C, Zweckstetter, Markus, Mandelkow, Eckhard, Sticht, Heinrich, Funke, Susanne Aileen

Volltext

Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule von Kicuntod, Jintawee, Alkhashrom, Sewar, Hage, Sigrun, Diewald, Benedikt, Muller, Regina, Hahn, Friedrich, Lischka, Peter, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred

Volltext

High-resolution crystal structures of two prototypical β- and γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity von Muller, Yves A., Häge, Sigrun, Alkhashrom, Sewar, Höllriegl, Tobias, Weigert, Sebastian, Dolles, Simon, Hof, Kerstin, Walzer, Sascha A., Egerer-Sieber, Claudia, Conrad, Marcus, Holst, Stephanie, Lösing, Josephine, Sonntag, Eric, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred

Volltext

The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity von Schweininger, Johannes, Kriegel, Mark, Häge, Sigrun, Conrad, Marcus, Alkhashrom, Sewar, Lösing, Josephine, Weiler, Sigrid, Tillmanns, Julia, Egerer-Sieber, Claudia, Decker, Andrea, Lenac Roviš, Tihana, Eichler, Jutta, Sticht, Heinrich, Marschall, Manfred, Muller, Yves A.

Volltext

A novel D-amino acid peptide with therapeutic potential (ISAD1) inhibits aggregation of neurotoxic disease-relevant mutant Tau and prevents Tau toxicity in vitro von Aillaud, Isabelle, Kaniyappan, Senthilvelrajan, Chandupatla, Ram Reddy, Ramirez, Lisa Marie, Alkhashrom, Sewar, Eichler, Jutta, Horn, Anselm H C, Zweckstetter, Markus, Mandelkow, Eckhard, Sticht, Heinrich, Funke, Susanne Aileen

Volltext

High-resolution crystal structures of two prototypical ?- and ?-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity von Muller, Yves A., Haege, Sigrun, Alkhashrom, Sewar, Hoellriegl, Tobias, Weigert, Sebastian, Dolles, Simon, Hof, Kerstin, Walzer, Sascha A., Egerer-Sieber, Claudia, Conrad, Marcus, Holst, Stephanie, Loesing, Josephine, Sonntag, Eric, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred

Volltext