In silico drug discovery of SIRT2 inhibitors from natural source as anticancer agents von Ibrahim, Mahmoud A. A., Abdeljawaad, Khlood A. A., Roshdy, Eslam, Mohamed, Dina E. M., Ali, Taha F. S., Gabr, Gamal A., Jaragh-Alhadad, Laila A., Mekhemer, Gamal A. H., Shawky, Ahmed M., Sidhom, Peter A., Abdelrahman, Alaa H. M.

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Combination of an Oxindole Derivative with (-)-β-Elemene Alters Cell Death Pathways in FLT3/ITD + Acute Myeloid Leukemia Cells von Alanazi, Jowaher, Bender, Onur, Dogan, Rumeysa, Malik, Jonaid Ahmad, Atalay, Arzu, Ali, Taha F S, Beshr, Eman A M, Shawky, Ahmed M, Aly, Omar M, Alqahtani, Yasir Nasser H, Anwar, Sirajudheen

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The First Pentacyclic Triterpenoid Gypsogenin Derivative Exhibiting Anti-ABL1 Kinase and Anti-chronic Myelogenous Leukemia Activities von Ciftci, Halil Ibrahim, Ozturk, Safiye Emirdag, Ali, Taha F. S., Radwan, Mohamed O., Tateishi, Hiroshi, Koga, Ryoko, Ocak, Zeynep, Can, Mustafa, Otsuka, Masami, Fujita, Mikako

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Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor von Soudi, Aya, Bender, Onur, Celik, Ismail, El-Hafeez, Amer Ali Abd, Dogan, Rumeysa, Atalay, Arzu, Elkaeed, Eslam B, Alsfouk, Aisha A, Abdelhafez, Elshimaa M N, Aly, Omar M, Sippl, Wolfgang, Ali, Taha F S

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Indole-based FLT3 inhibitors and related scaffolds as potential therapeutic agents for acute myeloid leukemia von Ezelarab, Hend A. A., Ali, Taha F. S., Abbas, Samar H., Hassan, Heba A., Beshr, Eman A. M.

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An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models von Toma, Tsugumasa, Miyakawa, Nobukazu, Arakaki, Yuiichi, Watanabe, Takuro, Nakahara, Ryosei, Ali, Taha F. S., Biswas, Tanima, Todaka, Mikio, Kondo, Tatsuya, Fujita, Mikako, Otsuka, Masami, Araki, Eiichi, Tateishi, Hiroshi

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Design, Synthesis, and Biological Evaluation of Novel 1,3,4-Thiadiazole Derivatives as Potential Antitumor Agents against Chronic Myelogenous Leukemia: Striking Effect of Nitrothia... von Altıntop, Mehlika Dilek, Ciftci, Halil Ibrahim, Radwan, Mohamed O, Sever, Belgin, Kaplancıklı, Zafer Asım, Ali, Taha F S, Koga, Ryoko, Fujita, Mikako, Otsuka, Masami, Özdemir, Ahmet

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In Vitro and In Silico Evaluation of Anticancer Activity of New Indole-Based 1,3,4-Oxadiazoles as EGFR and COX-2 Inhibitors von Sever, Belgin, Altintop, Mehlika Dilek, Ozdemir, Ahmet, Ciftci, Gulsen Akalin, Ellakwa, Doha E., Tateishi, Hiroshi, Radwan, Mohamed O., Ibrahim, Mahmoud A. A., Otsuka, Masami, Fujita, Mikako, Ciftci, Halil, Ali, Taha F. S.

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New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization von Ezelarab, Hend A. A., Ali, Taha F. S., Abbas, Samar H., Sayed, Ahmed M., Beshr, Eman A. M., Hassan, Heba A.

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Antiproliferative S -Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement von Radwan, Mohamed O, Ciftci, Halil I, Ali, Taha F S, Ellakwa, Doha E, Koga, Ryoko, Tateishi, Hiroshi, Nakata, Akiko, Ito, Akihiro, Yoshida, Minoru, Okamoto, Yoshinari, Fujita, Mikako, Otsuka, Masami

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Novel Inhibitor for Downstream Targeting of Transforming Growth Factor-β Signaling to Suppress Epithelial to Mesenchymal Transition and Cell Migration von Toma, Tsugumasa, Tateishi, Hiroshi, Kawakami, Kensaku, Ali, Taha F S, Kamo, Masahiro, Monde, Kazuaki, Nakashima, Yuta, Fujita, Mikako, Otsuka, Masami

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Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity von I Ciftci, Halil, O Radwan, Mohamed, E Ozturk, Safiye, Ulusoy, N Gokce, Sozer, Ece, E Ellakwa, Doha, Ocak, Zeynep, Can, Mustafa, F S Ali, Taha, I Abd-Alla, Howaida, Yayli, Nurettin, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako

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New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors von Fareed, Momen R., Shoman, Mai E., Hamed, Mohammed I. A., Badr, Mohamed, Bogari, Hanin A., Elhady, Sameh S., Ibrahim, Tarek S., Abuo-Rahma, Gamal El-Din A., Ali, Taha F. S.

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Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition von Al-Wahaibi, Lamya H, Elshamsy, Ali M, Ali, Taha F S, Youssif, Bahaa G M, Bräse, S, Abdel-Aziz, Mohamed, El-Koussi, Nawal A

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A Dithiol Compound Binds to the Zinc Finger Protein TRAF6 and Suppresses Its Ubiquitination von Koga, Ryoko, Radwan, Mohamed O., Ejima, Tomohiko, Kanemaru, Yosuke, Tateishi, Hiroshi, Ali, Taha F. S., Ciftci, Halil Ibrahim, Shibata, Yuri, Taguchi, Yuu, Inoue, Jun‐ichiro, Otsuka, Masami, Fujita, Mikako

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Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR‑2 Inhibitors von Al-Wahaibi, Lamya H., Elshamsy, Ali M., Ali, Taha F. S., Youssif, Bahaa G. M., Bräse, Stefan, Abdel-Aziz, Mohamed, El-Koussi, Nawal A.

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Applying Different Techniques to Improve the Bioavailability of Candesartan Cilexetil Antihypertensive Drug von Aly, Usama Farghaly, Sarhan, Hatem Abdelmonsef, Ali, Taha F. S., Sharkawy, Hosny Abd El-Bakey

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Discovery of Azaindolin-2-One as a Dual Inhibitor of GSK3β and Tau Aggregation with Potential Neuroprotective Activity von Ali, Taha F S, Ciftci, Halil I, Radwan, Mohamed O, Roshdy, Eslam, Shawky, Ahmed M, Abourehab, Mohammed A S, Tateishi, Hiroshi, Otsuka, Masami, Fujita, Mikako

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The protective role of two oxindole derivatives is mediated by modulating NLRP3/caspase-1 and PI3K/AKT pathways in a preclinical animal model of hepatic ischemia reperfusion injury von Eldafashi, Nardeen, Waaz, Shaimaa, Ali, Taha F.S., Zaki, Marco Y.W., Nazmy, Maiiada Hassan, Fathy, Moustafa

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Discovery of novel thienoquinoline-2-carboxamide chalcone derivatives as antiproliferative EGFR tyrosine kinase inhibitors von Abdelbaset, Mahmoud S., Abdel-Aziz, Mohamed, Ramadan, Mohamed, Abdelrahman, Mostafa H., Abbas Bukhari, Syed Nasir, Ali, Taha F.S., Abuo-Rahma, Gamal El-Din A.

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