Synthesis of novel 2H-spiro[1-benzofuran-3,4′-piperidin]ol scaffolds von Leflemme, Nicolas, Stoit, Axel R., Borghese, Alfio

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Crystal forms of LY334370 HCl: Isolation, Solid‐State Characterization, and Physicochemical Properties von Reutzel‐Edens, Susan M., Kleemann, Rita L., Lewellen, Peggy L., Borghese, Alfio L., Antoine, Luc J.

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Development of a Scalable Process for the Synthesis of trans-2-Methylcyclopropanecarboxylic Acid von Delhaye, Laurent, Stevens, Christophe, Merschaert, Alain, Delbeke, Pieter, Briône, Willy, Tilstam, Ulf, Borghese, Alfio, Geldhof, Geoffroy, Diker, Khalid, Dubois, Aurélie, Barberis, Mario, Casarubios, Luis

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Process Development and Pilot-Plant Synthesis of (2-Chlorophenyl)[2-(phenylsulfonyl)pyridin-3-yl]methanone von Kopach, Michael E, Kobierski, Michael E, Coffey, D. Scott, Alt, Charles A, Zhang, Tony, Borghese, Alfio, Trankle, William G, Roberts, Dilwyn J, Moynihan, Humphrey, Lorenz, Kurt, McNamara, Orla A, Kissane, Marie, Maguire, Anita R

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The ring opening of 3,4-dichloro-1,2,5-thiadiazole with metal amides. A new synthesis of 3,4-disubstituted-1,2,5-thiadiazoles von Merschaert, Alain, Boquel, Pascal, Gorissen, Hugo, Hoeck, Jean-Pierre Van, Borghese, Alfio, Antoine, Luc, Mancuso, Vincent, Mockel, Anne, Vanmarsenille, Michel

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Novel Approaches towards the LTD4/E4 Antagonist, LY290154 von Merschaert, Alain, Boquel, Pascal, Van Hoeck, Jean-Pierre, Gorissen, Hugo, Borghese, Alfio, Bonnier, Benjamin, Mockel, Anne, Napora, Freddy

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Efficient Fast Screening Methodology for Optical Resolution Agents:  Solvent Effects Are Used To Affect the Efficiency of the Resolution Process von Borghese, Alfio, Libert, Valery, Zhang, Tony, Alt, Charles A.

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Novel chemoselective reduction of the tetrahydro-4-pyridyl versus indole moiety governed by electron donation: first X-ray evidence for indolopiperidyl–borane complexation von Borghese, Alfio, Antoine, Luc, Stephenson, Gregory

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Novel Approaches towards the LTD 4 /E 4 Antagonist, LY290154 von Merschaert, Alain, Boquel, Pascal, Van Hoeck, Jean-Pierre, Gorissen, Hugo, Borghese, Alfio, Bonnier, Benjamin, Mockel, Anne, Napora, Freddy

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Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine von BORGHESE ALFIO

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Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine von Borghese, Alfio

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PROCESS FOR PREPARING AN INTERMEDIATE USEFUL FOR THE ASYMMETRIC SYNTHESIS OF DULOXETINE von BORGHESE, ALFIO

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PROCESS FOR PREPARING AN INTERMEDIATE USEFUL FOR THE ASYMMETRIC SYNTHESIS OF DULOXETINE von BORGHESE, ALFIO

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PROCESSES FOR THE PREPARATION OF 3,4-SUBSTITUTED-1,2,5-THIADIAZOLES AND INTERMEDIATES THEREOF von MERSCHAERT ALAIN, BORGHESE ALFIO, MANCUSO VINCENZO

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NOVEL CRYSTALLINE FORMS OF <2-[1-(3,5-BIS-TRIFLUOROMETHYL-BENZYL)-5-PYRIDIN-4-YL-1H-[1,2,3]TRIAZOL-4-YL]-PYRIDIN-3-YL>-(2-CHLOROPHENYL)-METHANONE von STEVEN WAYNE PEDERSEN, CARSTEN WEBER, PAMELA KAYE FOOTMAN, SHELLA LENYONGA TAMEZE, CARSTEN TIMPE, SUSAN MARIE REUTZEL-EDENS, DAVID SCOTT COFFEY, ALFIO BORGHESE

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formas cristalinas iv e v de {2-[1-(3,5-bis-trifluorometilbenzil)-5-piridin-4-il-1h-[1,2,3]triazol-4-il]-piridin-3-il)-(2-clorofenil)-metanona, (2-clorofenil)-[2-(2-hidróxi-2-pirid... von Carsten Timpe, Sheila Lenyonga Tameze, Carsten Weber, David Scott Coffey, Susan Marie Reutzel-Edens, Pamela Kaye Footman, Alfio Borghese, Steven Wayne Pedersen

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PROCESSES FOR THE PREPARATION OF 3,4-SUBSTITUTED-1,2,5-THIADIAZOLES AND INTERMEDIATES THEREOF von MANCUSO, VINCENZO, MERSCHAERT, ALAIN, BORGHESE, ALFIO

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PROCESSES FOR THE PREPARATION OF 3,4-SUBSTITUTED-1,2,5-THIADIAZOLES AND INTERMEDIATES THEREOF von MANCUSO, VINCENZO, MERSCHAERT, ALAIN, BORGHESE, ALFIO

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PROCESSES FOR THE PREPARATION OF 3,4-SUBSTITUTED-1,2,5-THIADIAZOLES AND INTERMEDIATES THEREOF von MANCUSO, VINCENZO, MERSCHAERT, ALAIN, BORGHESE, ALFIO

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formas cristalinas iv e v de {2-[1-(3,5-bis-trifluorometilbenzil)-5-piridin-4-il-1h-[1,2,3]triazol-4-il]-piridin-3-il)-(2-clorofenil)-metanona, (2-clorofenil)-[2-(2-hidróxi-2-pirid... von Carsten Timpe, Sheila Lenyonga Tameze, Carsten Weber, David Scott Coffey, Susan Marie Reutzel-Edens, Pamela Kaye Footman, Alfio Borghese, Steven Wayne Pedersen

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