A biologically active fructan from the roots of Arctium lappa L., var. Herkules von Kardošová, A., Ebringerová, A., Alföldi, J., Nosál’ová, G., Fraňová, S., Hřı́balová, V.

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Structural and solution properties of corn cob heteroxylans von Ebringerová, A., Hromádková, Z., Alföldi, J., Berth, G.

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Author Correction: Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes von Wang, Q, Pierce-Hoffman, E, Cummings, BB, Alföldi, J, Francioli, LC, Gauthier, LD, Hill, AJ, O'Donnell-Luria, AH, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Karczewski, KJ, MacArthur, DG

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Transcript expression-aware annotation improves rare variant interpretation von Cummings, BB, Karczewski, KJ, Kosmicki, JA, Seaby, EG, Watts, NA, Singer-Berk, M, Mudge, JM, Karjalainen, J, Satterstrom, FK, O'Donnell-Luria, AH, Poterba, T, Seed, C, Solomonson, M, Alföldi, J, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Daly, MJ, MacArthur, DG

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Evaluating potential drug targets through human loss-of-function genetic variation von Minikel, EV, Karczewski, KJ, Martin, HC, Cummings, BB, Whiffin, N, Rhodes, D, Alföldi, J, Trembath, RC, Van Heel, DA, Daly, MJ, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Schreiber, SL, MacArthur, DG

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The effect of LRRK2 loss-of-function variants in humans von Whiffin, N, Armean, IM, Kleinman, A, Marshall, JL, Minikel, EV, Goodrich, JK, Quaife, NM, Cole, JB, Wang, Q, Karczewski, KJ, Cummings, BB, Francioli, L, Laricchia, K, Guan, A, Alipanahi, B, Morrison, P, Baptista, MAS, Merchant, KM, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Ware, JS, Havulinna, AS, Iliadou, B, Lee, J-J, Nadkarni, GN, Whiteman, C, 23andMe Research Team, Daly, M, Esko, T, Hultman, C, Loos, RJF, Milani, L, Palotie, A, Pato, C, Pato, M, Saleheen, D, Sullivan, PF, Alföldi, J, Cannon, P, MacArthur, DG

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Human loss-of-function variants suggest that partial LRRK2 reduction is not associated with severe disease von Whiffin, N, Armean, IM, Kleinman, A, Marshall, JL, Minikel, EV, Goodrich, JK, Quaife, N, Cole, JB, Wang, Q, Karczewski, KJ, Cummings, BB, Francioli, L, Laricchia, K, Guan, A, Alipanahi, B, Morrison, P, Baptista, MAS, Merchant, KM, Genome Aggregation Database Production Team^, Genome Aggregation Database Consortium, Ware, J, Havulinna, AS, Iliadou, B, Lee, J-J, Nadkarni, GN, Whiteman, C, Daly, M, Esko, T, Hultman, C, Loos, RJF, Milani, L, Palotie, A, Pato, C, Pato, M, Saleheen, D, Sullivan, PF, Alföldi, J, Cannon, P, MacArthur, DG

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Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals von Whiffin, N, Karczewski, KJ, Zhang, X, Chothani, S, Smith, MJ, Evans, DG, Roberts, AM, Quaife, NM, Schafer, S, Rackham, O, Alföldi, J, O'Donnell-Luria, AH, Francioli, LC, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Cook, SA, Barton, PJR, MacArthur, DG, Ware, JS

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Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals von Whiffin, N, Karczewski, KJ, Zhang, X, Chothani, S, Smith, MJ, Evans, DG, Roberts, AM, Quaife, NM, Schafer, S, Rackham, O, Alföldi, J, O'Donnell-Luria, AH, Francioli, LC, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Cook, SA, Barton, PJR, MacArthur, DG, Ware, JS

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A structural variation reference for medical and population genetics von Collins, RL, Brand, H, Karczewski, KJ, Zhao, X, Alföldi, J, Francioli, LC, Khera, AV, Lowther, C, Gauthier, LD, Wang, H, Watts, NA, Solomonson, M, O'Donnell-Luria, A, Baumann, A, Munshi, R, Walker, M, Whelan, CW, Huang, Y, Brookings, T, Sharpe, T, Stone, MR, Valkanas, E, Fu, J, Tiao, G, Laricchia, KM, Ruano-Rubio, V, Stevens, C, Gupta, N, Cusick, C, Margolin, L, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Taylor, KD, Lin, HJ, Rich, SS, Post, WS, Chen, Y-DI, Rotter, JI, Nusbaum, C, Philippakis, A, Lander, E, Gabriel, S, Neale, BM, Kathiresan, S, Daly, MJ, Banks, E, MacArthur, DG, Talkowski, ME

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The mutational constraint spectrum quantified from variation in 141,456 humans von Karczewski, KJ, Francioli, LC, Tiao, G, Cummings, BB, Alföldi, J, Wang, Q, Collins, RL, Laricchia, KM, Ganna, A, Birnbaum, DP, Gauthier, LD, Brand, H, Solomonson, M, Watts, NA, Rhodes, D, Singer-Berk, M, England, EM, Seaby, EG, Kosmicki, JA, Walters, RK, Tashman, K, Farjoun, Y, Banks, E, Poterba, T, Wang, A, Seed, C, Whiffin, N, Chong, JX, Samocha, KE, Pierce-Hoffman, E, Zappala, Z, O’Donnell-Luria, AH, Vallabh Minikel, E, Weisburd, B, Lek, M, Ware, JS, Vittal, C, Armean, IM, Bergelson, L, Cibulskis, K, Connolly, JM, Covarrubias, M, Donnelly, S, Ferriera, S, Gabriel, S, Gentry, J, Gupta, N, Jeandet, T, Kaplan, D, Llanwarne, C, Munshi, J, Novod, S, Petrillo, N, Roazen, D, Ruano-Rubio, V, Saltzman, A, Schleicher, M, Soto, J, Tibbetts, K, Tolonen, C, Wade, G, Talkowski, ME, Genome Aggregation Database (gnomAD) Consortium, Neale, BM, Daly, MJ, MacArthur, DG

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Water-soluble p-carboxybenzylated beechwood 4- O-methylglucuronoxylan: structural features and properties von Ebringerová, A., Alföldi, J., Hromádková, Z., Pavlov, G.M., Harding, S.E.

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Enzymatic and ultrasonic depolymerization of carboxymethylated β-1,3-D-glucans derived from saccharomyces cerevisiae von Machová, E., Kogan, G., Alföldi, J., Šotés, L., Šandula, J.

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Cyclodextrin derivative of hyaluronan von Šoltés, L., Mendichi, R., Machovà, E., Steiner, B., Alföldi, J., Sasinkovà, V., Bystrický, S., Balog, K.

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Galactoglucomannan from the secondary cell wall of Picea abies L. Karst von Capek, Peter, Kubačková, Marta, Alföldi, Juraj, Bilisics, Ladislav, Lišková, Desana, Kákoniová, Daniela

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A genomic mutational constraint map using variation in 76,156 human genomes von Chen, Siwei, Francioli, Laurent C., Goodrich, Julia K., Collins, Ryan L., Kanai, Masahiro, Wang, Qingbo, Alföldi, Jessica, Watts, Nicholas A., Vittal, Christopher, Gauthier, Laura D., Poterba, Timothy, Wilson, Michael W., Tarasova, Yekaterina, Phu, William, Grant, Riley, Yohannes, Mary T., Koenig, Zan, Farjoun, Yossi, Banks, Eric, Donnelly, Stacey, Gabriel, Stacey, Gupta, Namrata, Ferriera, Steven, Tolonen, Charlotte, Novod, Sam, Bergelson, Louis, Roazen, David, Ruano-Rubio, Valentin, Covarrubias, Miguel, Llanwarne, Christopher, Petrillo, Nikelle, Wade, Gordon, Jeandet, Thibault, Munshi, Ruchi, Tibbetts, Kathleen, O’Donnell-Luria, Anne, Solomonson, Matthew, Seed, Cotton, Martin, Alicia R., Talkowski, Michael E., Rehm, Heidi L., Daly, Mark J., Tiao, Grace, Neale, Benjamin M., MacArthur, Daniel G., Karczewski, Konrad J.

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A comparative genomics multitool for scientific discovery and conservation von Genereux, Diane P., Serres, Aitor, Armstrong, Joel, Johnson, Jeremy, Marinescu, Voichita D., Muren, Eva, Juan, David, Bejerano, Gill, Casewell, Nicholas R., Chemnick, Leona G., Damas, Joana, Di Palma, Federica, Diekhans, Mark, Fiddes, Ian T., Garber, Manuel, Gladyshev, Vadim N., Goodman, Linda, Haerty, Wilfried, Houck, Marlys L., Hubley, Robert, Kivioja, Teemu, Koepfli, Klaus-Peter, Kuderna, Lukas F. K., Lander, Eric S., Meadows, Jennifer R. S., Murphy, William J., Nash, Will, Noh, Hyun Ji, Nweeia, Martin, Pfenning, Andreas R., Pollard, Katherine S., Ray, David A., Shapiro, Beth, Smit, Arian F. A., Springer, Mark S., Steiner, Cynthia C., Swofford, Ross, Taipale, Jussi, Teeling, Emma C., Turner-Maier, Jason, Alfoldi, Jessica, Birren, Bruce, Ryder, Oliver A., Lewin, Harris A., Paten, Benedict, Marques-Bonet, Tomas, Lindblad-Toh, Kerstin, Karlsson, Elinor K.

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Stereochemistry of the hydrolysis of glycosidic linkage by endo-β-1,4-xylanases of Trichoderma reesei von Biely, Peter, Kremnický, Lubomír, Alföldi, Juraj, Tenkanen, Maija

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The effect of LRRK2 loss-of-function variants in humans von Whiffin, Nicola, Armean, Irina M., Kleinman, Aaron, Marshall, Jamie L., Minikel, Eric V., Goodrich, Julia K., Quaife, Nicholas M., Cole, Joanne B., Wang, Qingbo, Karczewski, Konrad J., Cummings, Beryl B., Francioli, Laurent, Laricchia, Kristen, Guan, Anna, Alipanahi, Babak, Morrison, Peter, Baptista, Marco A. S., Merchant, Kalpana M., Ware, James S., Havulinna, Aki S., Iliadou, Bozenna, Lee, Jung-Jin, Nadkarni, Girish N., Whiteman, Cole, Daly, Mark, Esko, Tõnu, Hultman, Christina, Loos, Ruth J. F., Milani, Lili, Palotie, Aarno, Pato, Carlos, Pato, Michele, Saleheen, Danish, Sullivan, Patrick F., Alföldi, Jessica, Cannon, Paul, MacArthur, Daniel G.

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Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum von Ganna, Andrea, Satterstrom, F. Kyle, Zekavat, Seyedeh M., Das, Indraniel, Kurki, Mitja I., Churchhouse, Claire, Alfoldi, Jessica, Martin, Alicia R., Havulinna, Aki S., Byrnes, Andrea, Thompson, Wesley K., Nielsen, Philip R., Karczewski, Konrad J., Saarentaus, Elmo, Rivas, Manuel A., Gupta, Namrata, Pietiläinen, Olli, Emdin, Connor A., Lescai, Francesco, Bybjerg-Grauholm, Jonas, Flannick, Jason, Mercader, Josep M., Udler, Miriam, Laakso, Markku, Salomaa, Veikko, Hultman, Christina, Ripatti, Samuli, Hämäläinen, Eija, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Nordentoft, Merete, Hougaard, David M., Mors, Ole, Werge, Thomas, Mortensen, Preben Bo, MacArthur, Daniel, Daly, Mark J., Sullivan, Patrick F., Locke, Adam E., Palotie, Aarno, Børglum, Anders D., Kathiresan, Sekar, Neale, Benjamin M.

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