Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection von Karoyan, Philippe, Vieillard, Vincent, Gómez-Morales, Luis, Odile, Estelle, Guihot, Amélie, Luyt, Charles-Edouard, Denis, Alexis, Grondin, Pascal, Lequin, Olivier

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Proteomic and toxinological characterization of Peruvian pitviper Bothrops brazili (“jergón shushupe”), venom von Rodrigues, Carolina Rego, Molina, Denis Alexis Molina, Silva de Assis, Thamyres C., Liberato, Camila, Melo-Braga, Marcella N., Ferreyra, César Bonilla, Cárdenas, Javier, Costal-Oliveira, Fernanda, Guerra-Duarte, Clara, Chávez-Olórtegui, Carlos

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The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis von Liddle, John, Beaufils, Benjamin, Binnie, Margaret, Bouillot, Anne, Denis, Alexis A., Hann, Michael M., Haslam, Carl P., Holmes, Duncan S., Hutchinson, Jon P., Kranz, Michael, McBride, Andrew, Mirguet, Olivier, Mole, Damian J., Mowat, Christopher G., Pal, Sandeep, Rowland, Paul, Trottet, Lionel, Uings, Iain J., Walker, Ann L., Webster, Scott P.

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From Triclosan toward the Clinic: Discovery of Nonbiocidal, Potent FabI Inhibitors for the Treatment of Resistant Bacteria von Gerusz, Vincent, Denis, Alexis, Faivre, Fabien, Bonvin, Yannick, Oxoby, Mayalen, Briet, Sophia, LeFralliec, Géraldine, Oliveira, Chrystelle, Desroy, Nicolas, Raymond, Cédric, Peltier, Laëtitia, Moreau, François, Escaich, Sonia, Vongsouthi, Vanida, Floquet, Stéphanie, Drocourt, Elodie, Walton, Armelle, Prouvensier, Laure, Saccomani, Marc, Durant, Lionel, Genevard, Jean-Marie, Sam-Sambo, Vanessa, Soulama-Mouze, Coralie

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Towards Gram-negative antivirulence drugs: New inhibitors of HldE kinase von Desroy, Nicolas, Moreau, François, Briet, Sophia, Fralliec, Géraldine Le, Floquet, Stephanie, Durant, Lionel, Vongsouthi, Vanida, Gerusz, Vincent, Denis, Alexis, Escaich, Sonia

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Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors von Dublanchet, Anne-Claude, Ducrot, Pierre, Andrianjara, Charles, O’Gara, Margaret, Morales, Renaud, Compère, Delphine, Denis, Alexis, Blais, Stéphane, Cluzeau, Philippe, Courté, Karine, Hamon, Jacques, Moreau, François, Prunet, Marie-Laure, Tertre, Anita

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Synthesis and Antibacterial Activity of Ketolides (6-O-Methyl-3-oxoerythromycin Derivatives):  A New Class of Antibacterials Highly Potent Against Macrolide-Resistant and -Suscepti... von Agouridas, Constantin, Denis, Alexis, Auger, Jean-Michel, Benedetti, Yannick, Bonnefoy, Alain, Bretin, François, Chantot, Jean-François, Dussarat, Arlette, Fromentin, Claude, D'Ambrières, Solange Gouin, Lachaud, Sylvette, Laurin, Patrick, Le Martret, Odile, Loyau, Véronique, Tessot, Nicole

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Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens von Denis, Alexis, Agouridas, Constantin, Auger, Jean-Michel, Benedetti, Yannick, Bonnefoy, Alain, Bretin, François, Chantot, Jean-François, Dussarat, Arlette, Fromentin, Claude, Gouin D'Ambrières, Solange, Lachaud, Sylvette, Laurin, Patrick, Le Martret, Odile, Loyau, Véronique, Tessot, Nicole, Pejac, Jean-Marie, Perron, Sébastien

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A Potent and Selective Kallikrein-5 Inhibitor Delivers High Pharmacological Activity in Skin from Patients with Netherton Syndrome von Liddle, John, Beneton, Veronique, Benson, Matthew, Bingham, Ryan, Bouillot, Anne, Boullay, Anne-Benedicte, Brook, Eloisa, Cryan, Jenni, Denis, Alexis, Edgar, Emma, Ferrie, Alan, Fouchet, Marie-Helene, Grillot, Didier, Holmes, Duncan S., Howes, Ashleigh, Krysa, Gael, Laroze, Alain, Lennon, Mark, McClure, Fiona, Moquette, Alexandre, Nicodeme, Edwige, Santiago, Brandon, Santos, Leandro, Smith, Kathrine J., Thorpe, James H., Thripp, Gary, Trottet, Lionel, Walker, Ann L., Ward, Simon A., Wang, Yichen, Wilson, Steve, Pearce, Andrew C., Hovnanian, Alain

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An overview of Tityus cisandinus scorpion venom: Transcriptome and mass fingerprinting reveal conserved toxin homologs across the Amazon region and novel lipolytic components von Kalapothakis, Yan, Miranda, Kelton, Molina, Denis Alexis Molina, Conceição, Izabela Mamede Costa Andrade, Larangote, Débora, Op den Camp, Huub J.M., Kalapothakis, Evanguedes, Chávez-Olórtegui, Carlos, Borges, Adolfo

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A unique peptide deformylase platform to rationally design and challenge novel active compounds von Fieulaine, Sonia, Alves de Sousa, Rodolphe, Maigre, Laure, Hamiche, Karim, Alimi, Mickael, Bolla, Jean-Michel, Taleb, Abbass, Denis, Alexis, Pagès, Jean-Marie, Artaud, Isabelle, Meinnel, Thierry, Giglione, Carmela

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The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding von Liddle, John, Pearce, Andrew C., Arico-Muendel, Christopher, Belyanskaya, Svetlana, Brewster, Andrew, Brown, Murray, Chung, Chun-wa, Denis, Alexis, Dodic, Nerina, Dossang, Anthony, Eddershaw, Peter, Klimaszewska, Diana, Haq, Imran, Holmes, Duncan S., Jagger, Alistair, Jakhria, Toral, Jigorel, Emilie, Lind, Ken, Messer, Jeff, Neu, Margaret, Olszewski, Allison, Ronzoni, Riccardo, Rowedder, James, Rüdiger, Martin, Skinner, Steve, Smith, Kathrine J., Trottet, Lionel, Uings, Iain, Zhu, Zhengrong, Irving, James A., Lomas, David A.

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The development of highly potent and selective small molecule correctors of Z α 1 -antitrypsin misfolding von Liddle, John, Pearce, Andrew C, Arico-Muendel, Christopher, Belyanskaya, Svetlana, Brewster, Andrew, Brown, Murray, Chung, Chun-Wa, Denis, Alexis, Dodic, Nerina, Dossang, Anthony, Eddershaw, Peter, Klimaszewska, Diana, Haq, Imran, Holmes, Duncan S, Jagger, Alistair, Jakhria, Toral, Jigorel, Emilie, Lind, Ken, Messer, Jeff, Neu, Margaret, Olszewski, Allison, Ronzoni, Riccardo, Rowedder, James, Rüdiger, Martin, Skinner, Steve, Smith, Kathrine J, Trottet, Lionel, Uings, Iain, Zhu, Zhengrong, Irving, James A, Lomas, David A

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Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin von Lomas, David A, Irving, James A, Arico‐Muendel, Christopher, Belyanskaya, Svetlana, Brewster, Andrew, Brown, Murray, Chung, Chun‐wa, Dave, Hitesh, Denis, Alexis, Dodic, Nerina, Dossang, Anthony, Eddershaw, Peter, Klimaszewska, Diana, Haq, Imran, Holmes, Duncan S, Hutchinson, Jonathan P, Jagger, Alistair M, Jakhria, Toral, Jigorel, Emilie, Liddle, John, Lind, Ken, Marciniak, Stefan J, Messer, Jeff, Neu, Margaret, Olszewski, Allison, Ordonez, Adriana, Ronzoni, Riccardo, Rowedder, James, Rüdiger, Martin, Skinner, Steve, Smith, Kathrine J, Terry, Rebecca, Trottet, Lionel, Uings, Iain, Wilson, Steve, Zhu, Zhengrong, Pearce, Andrew C

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Development of a Series of Kynurenine 3‑Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis von Walker, Ann L, Ancellin, Nicolas, Beaufils, Benjamin, Bergeal, Marylise, Binnie, Margaret, Bouillot, Anne, Clapham, David, Denis, Alexis, Haslam, Carl P, Holmes, Duncan S, Hutchinson, Jonathan P, Liddle, John, McBride, Andrew, Mirguet, Olivier, Mowat, Christopher G, Rowland, Paul, Tiberghien, Nathalie, Trottet, Lionel, Uings, Iain, Webster, Scott P, Zheng, Xiaozhong, Mole, Damian J

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Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors von Walker, Ann L., Denis, Alexis, Bingham, Ryan P., Bouillot, Anne, Edgar, Emma V., Ferrie, Alan, Holmes, Duncan S., Laroze, Alain, Liddle, John, Fouchet, Marie-Helene, Moquette, Alexandre, Nassau, Pam, Pearce, Andrew C., Polyakova, Oxana, Smith, Kathrine J., Thomas, Pamela, Thorpe, James H., Trottet, Lionel, Wang, Yichen, Hovnanian, Alain

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The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies von Karoyan, Philippe, Vieillard, Vincent, Gómez-Morales, Luis, Odile, Estelle, Guihot, Amélie, Luyt, Charles-Edouard, Denis, Alexis, Grondin, Pascal, Lequin, Olivier

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Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection von Karoyan, Philippe, Vieillard, Vincent, Gómez-Morales, Luis, Odile, Estelle, Guihot, Amélie, Luyt, Charles-Edouard, Denis, Alexis, Grondin, Pascal, Lequin, Olivier

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Corrigendum to ‘Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors’ [Bioorg. Med. Chem. Lett. 29 (2019) 126675] von Walker, Ann L., Denis, Alexis, Bingham, Ryan P., Bouillot, Anne, Edgar, Emma V., Ferrie, Alan, Holmes, Duncan S., Laroze, Alain, Liddle, John, Fouchet, Marie-Helene, Moquette, Alexandre, Nassau, Pam, Pearce, Andrew C., Polyakova, Oxana, Smith, Kathrine J., Thomas, Pamela, Thorpe, James H., Trottet, Lionel, Wang, Yichen, Hovnanian, Alain

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Erratum: Corrigendum: A unique peptide deformylase platform to rationally design and challenge novel active compounds von Fieulaine, Sonia, Alves de Sousa, Rodolphe, Maigre, Laure, Hamiche, Karim, Alimi, Mickael, Bolla, Jean-Michel, Taleb, Abbass, Denis, Alexis, Pagès, Jean-Marie, Artaud, Isabelle, Meinnel, Thierry, Giglione, Carmela

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