FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer von Zaghdoudi, Sonia, Decaup, Emilie, Belhabib, Ismahane, Samain, Rémi, Cassant‐Sourdy, Stéphanie, Rochotte, Julia, Brunel, Alexia, Schlaepfer, David, Cros, Jérome, Neuzillet, Cindy, Strehaiano, Manon, Alard, Amandine, Tomasini, Richard, Rajeeve, Vinothini, Perraud, Aurélie, Mathonnet, Muriel, Pearce, Oliver MT, Martineau, Yvan, Pyronnet, Stéphane, Bousquet, Corinne, Jean, Christine

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Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma von Neuzillet, Cindy, Nicolle, Rémy, Raffenne, Jérôme, Tijeras‐Raballand, Annemilaï, Brunel, Alexia, Astorgues‐Xerri, Lucile, Vacher, Sophie, Arbateraz, Floriane, Fanjul, Marjorie, Hilmi, Marc, Samain, Rémi, Klein, Christophe, Perraud, Aurélie, Rebours, Vinciane, Mathonnet, Muriel, Bièche, Ivan, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne

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Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma von Neuzillet, Cindy, Nicolle, Rémy, Raffenne, Jérôme, Tijeras-Raballand, Annemilaï, Brunel, Alexia, Astorgues-Xerri, Lucile, Vacher, Sophie, Arbateraz, Floriane, Fanjul, Marjorie, Hilmi, Marc, Samain, Rémi, Klein, Christophe, Perraud, Aurélie, Rebours, Vinciane, Mathonnet, Muriel, Bièche, Ivan, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne

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Acquired chemoresistance in pancreatic adenocarcinoma: mechanisms involving a stromal ZBTB family transcription factor von Ludmila, Recoules, Hippolyte, Audureau, Jérôme, Raffenne, Rémi, Samain, Amandine, Alard, Alexia, Brunel, Marjorie, Fanjul, Ismahane, Belhabib, Isabelle, Van Seuningen, Charles, Theillet, Audrey, Vincent, Stéphane, Pyronnet, Remy, Nicolle, Yvan, Martineau, Christine, Jean, Corinne, Bousquet

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Abstract PO-088: Classification based on efficiency of mRNA translation reveals a metabolically-dependent subtype of pancreatic cancer von Shin, Sauyeun, Nicolle, Remy, Liauzun, Mehdi, Solorzano, Jacobo, Brunel, Alexia, Jean, Christine, Samain, Remi, Raffenne, Jerôme, Neuzillet, Cindy, Joffre, Carine, Rocci, Stephane, Iovanna, Juan, Dusetti, Nelson, Larsson, Ola, Pyronnet, Stephane, Bousquet, Corinne, Martineau, Yvan

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Metabolic crosstalk between serine-dependent PDA tumor cells and CAFs revealed by mRNA translation analysis in patient-derived xenografts von Sauyeun, Shin, Mehdi, Liauzun, Jacobo, Solorzano, Christine, Jean, Benjamin, Fourneaux, Morgane, Le Bras, Ismahane, Belhabib, Remi, Samain, Alexia, Brunel, Cindy, Neuzillet, Marion, Larroque, Carine, Joffre, Stephane, Rocchi, Aurelie, Perraud, Muriel, Mathonnet, Vera, Pancaldi, Laetitia, Linares, Juan, Iovanna, Nelson, Dusetti, Ola, Larsson, Remy, Nicolle, Stephane, Pyronnet, Corinne, Bousquet, Yvan, Martineau

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Identification of two cancer-associated fibroblast markers revealing stromal heterogeneity in sustaining cancer progression and chemoresistance von Brunel, Alexia, Samain, Rémi, Neuzillet, Cindy, Bousquet, Corinne

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Bioinformatical analysis of tumor cell with stroma crosstalk that impact aggressiveness of pancreatic ductal adenocarcinoma von Brunel, Alexia, Raffenne, J., Nicolle, R., Chastel, T., Fanjul, M., Perraud, A., Mathonnet, M., Vasseur, S., Dusetti, N., Martineau, Y., Jean, C., Bousquet, C.

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Abstract C034: Bioinformatical identification of cancer-associated-fibroblasts with tumor cells pro-migratory crosstalks depending on activin von Brunel, Alexia, Raffenne, Jérôme, Nicolle, Remy, Rooman, Ilse, Espinet, Elisa, Fanjul, Marjorie, Perraud, Aurélie, Mathonnet, Muriel, Vasseur, Sophie, Dusetti, Nelson, Martineau, Yvan, Jean, Christine, Bousquet, Corinne

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Heterogeneity of human pancreatic adenocarcinoma (PDAC) cancer-associated fibroblasts (CAF): subtype-A (periostin-positive) CAF is associated with aggressive tumor features and is... von Neuzillet, Cindy, Nicolle, Rémy, Tijeras-Raballand, Annemilaï, Hilmi, Marc, Richon, Sophie, Brunel, Alexia, Samain, Rémi, Sadanandam, Anguraj, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne

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Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages von Samain, Rémi, Brunel, Alexia, Douché, Thibault, Fanjul, Marjorie, Cassant-Sourdy, Stéphanie, Rochotte, Julia, Cros, Jérôme, Neuzillet, Cindy, Raffenne, Jérôme, Duluc, Camille, Perraud, Aurélie, Nigri, Jérémy, Gigoux, Véronique, Bieche, Ivan, Ponzo, Matteo, Carpentier, Gilles, Cascone, Ilaria, Tomasini, Richard, Schmid, Herbert A., Mathonnet, Muriel, Nicolle, Rémy, Bousquet, Marie-Pierre, Martineau, Yvan, Pyronnet, Stéphane, Jean, Christine, Bousquet, Corinne

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Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With MacrophagesSummary von Rémi Samain, Alexia Brunel, Thibault Douché, Marjorie Fanjul, Stéphanie Cassant-Sourdy, Julia Rochotte, Jérôme Cros, Cindy Neuzillet, Jérôme Raffenne, Camille Duluc, Aurélie Perraud, Jérémy Nigri, Véronique Gigoux, Ivan Bieche, Matteo Ponzo, Gilles Carpentier, Ilaria Cascone, Richard Tomasini, Herbert A. Schmid, Muriel Mathonnet, Rémy Nicolle, Marie-Pierre Bousquet, Yvan Martineau, Stéphane Pyronnet, Christine Jean, Corinne Bousquet

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