Exosomal microRNAs (exomiRs): Small molecules with a big role in cancer von Bhome, Rahul, Del Vecchio, Filippo, Lee, Gui-Han, Bullock, Marc D., Primrose, John N., Sayan, A. Emre, Mirnezami, Alex H.

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Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression von Bhome, Rahul, Goh, Rebecca W, Bullock, Marc D, Pillar, Nir, Thirdborough, Stephen M, Mellone, Massimiliano, Mirnezami, Reza, Galea, Dieter, Veselkov, Kirill, Gu, Quan, Underwood, Timothy J, Primrose, John N, De Wever, Olivier, Shomron, Noam, Sayan, A Emre, Mirnezami, Alex H

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Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4 von Hanley, Christopher J, Mellone, Massimiliano, Ford, Kirsty, Thirdborough, Steve M, Mellows, Toby, Frampton, Steven J, Smith, David M, Harden, Elena, Szyndralewiez, Cedric, Bullock, Marc, Noble, Fergus, Moutasim, Karwan A, King, Emma V, Vijayanand, Pandurangan, Mirnezami, Alex H, Underwood, Timothy J, Ottensmeier, Christian H, Thomas, Gareth J

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The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis von Ling, Hui, Pickard, Karen, Ivan, Cristina, Isella, Claudio, Ikuo, Mariko, Mitter, Richard, Spizzo, Riccardo, Bullock, Marc D, Braicu, Cornelia, Pileczki, Valentina, Vincent, Kimberly, Pichler, Martin, Stiegelbauer, Verena, Hoefler, Gerald, Almeida, Maria I, Hsiao, Annie, Zhang, Xinna, Primrose, John N, Packham, Graham K, Liu, Kevin, Bojja, Krishna, Gafà, Roberta, Xiao, Lianchun, Rossi, Simona, Song, Jian H, Vannini, Ivan, Fanini, Francesca, Kopetz, Scott, Zweidler-McKay, Patrick, Wang, Xuemei, Ionescu, Calin, Irimie, Alexandru, Fabbri, Muller, Lanza, Giovanni, Hamilton, Stanley R, Berindan-Neagoe, Ioana, Medico, Enzo, Mirnezami, Alex H, Calin, George A, Nicoloso, Milena S

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miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance von LEI ZHANG, PICKARD, Karen, THOMAS, Gareth J, PACKHAM, Graham, MIRNEZAMI, Alex H, JENEI, Veronika, BULLOCK, Marc D, BRUCE, Amanda, MITTER, Richard, KELLY, Gavin, PARASKEVA, Christos, STREFFORD, John, PRIMROSE, John

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MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression von Bullock, Marc D., Sayan, Abdulkadir E., Packham, Graham K., Mirnezami, Alex H.

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Risk-reducing surgery for individuals with cancer-predisposing germline pathogenic variants and no personal cancer history: a review of current UK guidelines von McCarthy, Rebecca L., Copson, Ellen, Tapper, William, Bolton, Helen, Mirnezami, Alex H., O’Neill, J. Robert, Patel, Nimesh N., Tischkowitz, Marc, Cutress, Ramsey I.

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Pathology and prognosis in pseudomyxoma peritonei: a review of 274 cases von Carr, Norman J, Finch, Jenny, Ilesley, Ian Charles, Chandrakumaran, Kandiah, Mohamed, Faheez, Mirnezami, Alex, Cecil, Tom, Moran, Brendan

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A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers von Hanley, Christopher J, Noble, Fergus, Ward, Matthew, Bullock, Marc, Drifka, Cole, Mellone, Massimiliano, Manousopoulou, Antigoni, Johnston, Harvey E, Hayden, Annette, Thirdborough, Steve, Liu, Yuming, Smith, David M, Mellows, Toby, Kao, W John, Garbis, Spiros D, Mirnezami, Alex, Underwood, Tim J, Eliceiri, Kevin W, Thomas, Gareth J

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Stem cell-like breast cancer cells with acquired resistance to metformin are sensitive to inhibitors of NADH-dependent CtBP dimerization von Banerjee, Arindam, Birts, Charles N, Darley, Matthew, Parker, Rachel, Mirnezami, Alex H, West, Jonathan, Cutress, Ramsey I, Beers, Stephen A, Rose-Zerilli, Matthew J J, Blaydes, Jeremy P

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Editor's Note: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance von Zhang, Lei, Pickard, Karen, Jenei, Veronika, Bullock, Marc D, Bruce, Amanda, Mitter, Richard, Kelly, Gavin, Paraskeva, Christos, Strefford, John, Primrose, John, Thomas, Gareth J, Packham, Graham, Mirnezami, Alex H

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A Preliminary Phenomenological Exploration of Experiences of the Empty Pelvis Syndrome Derived From a Modified‐Delphi: The Price of Survival Following Pelvic Exenteration for Advan... von West, Charles T., Denys, Andreas, Rose, Sam A., Pape, Eva, Ramshorst, Gabrielle H., Sutton, Paul A., Yano, Hideaki, West, Malcolm A., Mirnezami, Alex H., Calman, Lynn, Sodergren, Samantha C.

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The Colorectal Cancer Microenvironment: Strategies for Studying the Role of Cancer-Associated Fibroblasts von Bhome, Rahul, Mellone, Massimiliano, Emo, Katherine, Thomas, Gareth J., Sayan, A. Emre, Mirnezami, Alex H.

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Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR‐200 levels in extracellular vesicles von Bhome, Rahul, Emaduddin, Muhammad, James, Victoria, House, Louise M., Thirdborough, Stephen M., Mellone, Massimiliano, Tulkens, Joeri, Primrose, John N., Thomas, Gareth J., De Wever, Olivier, Mirnezami, Alex H., Sayan, A. Emre

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Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease von Chand, Manish, Siddiqui, Muhammed R S, Gupta, Ashish, Rasheed, Shahnawaz, Tekkis, Paris, Parvaiz, Amjad, Mirnezami, Alex H, Qureshi, Tahseen

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A rectal cancer feasibility study with an embedded phase III trial design assessing magnetic resonance tumour regression grade (mrTRG) as a novel biomarker to stratify management b... von Battersby, Nick J, Dattani, Mit, Rao, Sheela, Cunningham, David, Tait, Diana, Adams, Richard, Moran, Brendan J, Khakoo, Shelize, Tekkis, Paris, Rasheed, Shahnawaz, Mirnezami, Alex, Quirke, Philip, West, Nicholas P, Nagtegaal, Iris, Chong, Irene, Sadanandam, Anguraj, Valeri, Nicola, Thomas, Karen, Frost, Michelle, Brown, Gina

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The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer von Sreekumar, Rahul, Al‐Saihati, Hajir, Emaduddin, Muhammad, Moutasim, Karwan, Mellone, Massimiliano, Patel, Ashish, Kilic, Seval, Cetin, Metin, Erdemir, Sule, Navio, Marta Salgado, Lopez, Maria Antonette, Curtis, Nathan, Yagci, Tamer, Primrose, John N., Price, Brendan D., Berx, Geert, Thomas, Gareth J., Tulchinsky, Eugene, Mirnezami, Alex, Sayan, A. Emre

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Sequential assessment of bowel function and anorectal physiology after anterior resection for cancer: a prospective cohort study von Pilkington, Sophie A., Bhome, Rahul, Gilbert, Sally, Harris, Scott, Richardson, Carl, Dudding, Thomas C., Knight, John S., King, Andrew T., Mirnezami, Alex H., Beck, Nicholas E., Nichols, Paul H., Nugent, Karen P.

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Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs von Bullock, Marc D, Pickard, Karen, Mitter, Richard, Sayan, A Emre, Primrose, John N, Ivan, Cristina, Calin, George A, Thomas, Gareth J, Packham, Graham K, Mirnezami, Alex H

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A top-down view of the tumor microenvironment: structure, cells and signaling von Bhome, Rahul, Bullock, Marc D, Al Saihati, Hajir A, Goh, Rebecca W, Primrose, John N, Sayan, A Emre, Mirnezami, Alex H

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