Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae von North, Matthew, Steffen, Janet, Loguinov, Alex V, Zimmerman, Ginelle R, Vulpe, Chris D, Eide, David J

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Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde von Sobh, Amin, Loguinov, Alex, Stornetta, Alessia, Balbo, Silvia, Tagmount, Abderrahmane, Zhang, Luoping, Vulpe, Chris D

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Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity von Sobh, Amin, Loguinov, Alex, Yazici, Gulce Naz, Zeidan, Rola S, Tagmount, Abderrahmane, Hejazi, Nima S, Hubbard, Alan E, Zhang, Luoping, Vulpe, Chris D

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Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin von Fuqua, Brie K, Lu, Yan, Frazer, David M, Darshan, Deepak, Wilkins, Sarah J, Dunn, Linda, Loguinov, Alex V, Kogan, Scott C, Matak, Pavle, Chen, Huijun, Dunaief, Joshua L, Vulpe, Chris D, Anderson, Gregory J

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A genome-wide screen identifies yeast genes required for tolerance to technical toxaphene, an organochlorinated pesticide mixture von Gaytán, Brandon D, Loguinov, Alex V, Peñate, Xenia, Lerot, Jan-Michael, Chávez, Sebastián, Denslow, Nancy D, Vulpe, Chris D

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Molecular Toxicity Identification Evaluation (mTIE) Approach Predicts Chemical Exposure in Daphnia magna von Antczak, Philipp, Jo, Hun Je, Woo, Seonock, Scanlan, Leona, Poynton, Helen, Loguinov, Alex, Chan, Sarah, Falciani, Francesco, Vulpe, Chris

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Genome-wide functional profiling reveals genes required for tolerance to benzene metabolites in yeast von North, Matthew, Tandon, Vickram J, Thomas, Reuben, Loguinov, Alex, Gerlovina, Inna, Hubbard, Alan E, Zhang, Luoping, Smith, Martyn T, Vulpe, Chris D

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Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae von Jo, William J, Kim, Jeung Hyoun, Oh, Eric, Jaramillo, Daniel, Holman, Patricia, Loguinov, Alex V, Arkin, Adam P, Nislow, Corey, Giaever, Guri, Vulpe, Chris D

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Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes von De La Rosa, Vanessa Y, Asfaha, Jonathan, Fasullo, Michael, Loguinov, Alex, Li, Peng, Moore, Lee E, Rothman, Nathaniel, Nakamura, Jun, Swenberg, James A, Scelo, Ghislaine, Zhang, Luoping, Smith, Martyn T, Vulpe, Chris D

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Biomarker Discovery and Transcriptomic Responses in Daphnia magna exposed to Munitions Constituents von Garcia-Reyero, Natàlia, Poynton, Helen C, Kennedy, Alan J, Guan, Xin, Escalon, B. Lynn, Chang, Bonnie, Varshavsky, Julia, Loguinov, Alex V, Vulpe, Chris D, Perkins, Edward J

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Functional profiling discovers the dieldrin organochlorinated pesticide affects leucine availability in yeast von Gaytán, Brandon D, Loguinov, Alex V, Lantz, Stephen R, Lerot, Jan-Michael, Denslow, Nancy D, Vulpe, Chris D

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Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast von North, Matthew, Gaytán, Brandon D, Romero, Jr, Carlos, De La Rosa, Vanessa Y, Loguinov, Alex, Smith, Martyn T, Zhang, Luoping, Vulpe, Chris D

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Identification of Genes Involved in the Toxic Response of Saccharomyces cerevisiae against Iron and Copper Overload by Parallel Analysis of Deletion Mutants von Jo, William J., Loguinov, Alex, Chang, Michelle, Wintz, Henri, Nislow, Corey, Arkin, Adam P., Giaever, Guri, Vulpe, Chris D.

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Functional genomics indicates yeast requires Golgi/ER transport, chromatin remodeling, and DNA repair for low dose DMSO tolerance von Gaytán, Brandon D, Loguinov, Alex V, De La Rosa, Vanessa Y, Lerot, Jan-Michael, Vulpe, Chris D

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Functional Pathway Identification With CRISPR/Cas9 Genome-wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment With Dieldrin von Russo, Max, Sobh, Amin, Zhang, Ping, Loguinov, Alex, Tagmount, Abderrahmane, Vulpe, Chris D, Liu, Bin

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Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity von Zhao, Yun, Wei, Linqing, Tagmount, Abderrahmane, Loguinov, Alex, Sobh, Amin, Hubbard, Alan, McHale, Cliona M., Chang, Christopher J., Vulpe, Chris D., Zhang, Luoping

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Genome-Wide CRISPR/Cas9-Mediated Loss-of-Function Screening in Human Erythroleukemic Cells Identifies Novel Cellular Components Involved in Iron and Heme Trafficking von Sobh, Amin, Loguinov, Alex, Fraenkel, Paula, Vulpe, Chris D

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Propagation of functional estrogen receptor positive normal human breast cells in 3D cultures von Meng, Peng, Vaapil, Marica, Tagmount, Abderrahmane, Loguinov, Alex, Vulpe, Chris, Yaswen, Paul

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Genome-wide toxicogenomic study of the lanthanides sheds light on the selective toxicity mechanisms associated with critical materials von Pallares, Roger M., Faulkner, David, An, Dahlia D., Hébert, Solène, Loguinov, Alex, Proctor, Michael, Villalobos, Jonathan A., Bjornstad, Kathleen A., Rosen, Chris J., Vulpe, Christopher, Abergel, Rebecca J.

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Organochlorine Pesticide Dieldrin Suppresses Cellular Interferon-Related Antiviral Gene Expression von Russo, Max, Humes, Sara T, Figueroa, Ariana M, Tagmount, Abderrahmane, Zhang, Ping, Loguinov, Alex, Lednicky, John A, Sabo-Attwood, Tara, Vulpe, Chris D, Liu, Bin

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