A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis von Zhang, Lei, Kent, James E., Whitaker, Meredith, Young, David C., Herrmann, Dominik, Aleshin, Alexander E., Ko, Ying-Hui, Cingolani, Gino, Saad, Jamil S., Moody, D. Branch, Marassi, Francesca M., Ehrt, Sabine, Niederweis, Michael

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Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC) von Aleshin, Alexander E., Schraufstatter, Ingrid U., Stec, Boguslaw, Bankston, Laurie A., Liddington, Robert C., DiScipio, Richard G.

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Crystal Structure of C5b-6 Suggests Structural Basis for Priming Assembly of the Membrane Attack Complex von Aleshin, Alexander E., DiScipio, Richard G., Stec, Boguslaw, Liddington, Robert C.

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Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXRα von Chen, Liqun, Aleshin, Alexander E., Alitongbieke, Gulimiran, Zhou, Yuqi, Zhang, Xindao, Ye, Xiaohong, Hu, Mengjie, Ren, Gaoang, Chen, Ziwen, Ma, Yue, Zhang, Duo, Liu, Shuai, Gao, Weiwei, Cai, Lijun, Wu, Lingjuan, Zeng, Zhiping, Jiang, Fuquan, Liu, Jie, Zhou, Hu, Cadwell, Gregory, Liddington, Robert C., Su, Ying, Zhang, Xiao-kun

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TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response von Rozanov, Dmitri, Cheltsov, Anton, Sergienko, Eduard, Vasile, Stefan, Golubkov, Vladislav, Aleshin, Alexander E, Levin, Trevor, Traer, Elie, Hann, Byron, Freimuth, Julia, Alexeev, Nikita, Alekseyev, Max A, Budko, Sergey P, Bächinger, Hans Peter, Spellman, Paul

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Calcium-induced environmental adaptability of the blood protein vitronectin von Tian, Ye, Shin, Kyungsoo, Aleshin, Alexander E., Im, Wonpil, Marassi, Francesca M.

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Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island von Shiryaev, Sergey A., Aleshin, Alexander E., Muranaka, Norihito, Kukreja, Muskan, Routenberg, David A., Remacle, Albert G., Liddington, Robert C., Cieplak, Piotr, Kozlov, Igor A., Strongin, Alex Y.

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Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase von Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R, Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A, Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas D Y, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio

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The Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 Helicase von Chernov, Andrei V., Shiryaev, Sergey A., Aleshin, Alexander E., Ratnikov, Boris I., Smith, Jeffrey W., Liddington, Robert C., Strongin, Alex Y.

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Vitronectin, the major regulator of age-related macular degeneration von Shin, Kyungsoo, Kent, James E., Aleshin, Alexander E., Tian, Ye, Fujimoto, L. Miya, Singh, Chandan, Marassi, Francesca M.

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Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids von Aleshin, Alexander E., Yao, Yong, Iftikhar, Amer, Bobkov, Andrey A., Yu, Jinghua, Cadwell, Gregory, Klein, Michael G., Dong, Chuqiao, Bankston, Laurie A., Liddington, Robert C., Im, Wonpil, Powis, Garth, Marassi, Francesca M.

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Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells von Rozanov, Dmitri V, Savinov, Alexei Y, Golubkov, Vladislav S, Rozanova, Olga L, Postnova, Tatiana I, Sergienko, Eduard A, Vasile, Stefan, Aleshin, Alexander E, Rega, Michele F, Pellecchia, Maurizio, Strongin, Alex Y

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Crystal Structure and Evolution of a Prokaryotic Glucoamylase von Aleshin, Alexander E., Feng, Ping-Hua, Honzatko, Richard B., Reilly, Peter J.

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Switching the Substrate Specificity of the Two-Component NS2B-NS3 Flavivirus Proteinase by Structure-Based Mutagenesis von SHIRYAEV, Sergey A, RATNIKOV, Boris I, ALESHIN, Alexander E, KOZLOV, Igor A, NELSON, Nicholas A, LEBL, Michal, SMITH, Jeffrey W, LIDDINGTON, Robert C, STRONGIN, Alex Y

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Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold von Aleshin, Alexander E., Shiryaev, Sergey A., Strongin, Alex Y., Liddington, Robert C.

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Internal Cleavages of the Autoinhibitory Prodomain Are Required for Membrane Type 1 Matrix Metalloproteinase Activation, although Furin Cleavage Alone Generates Inactive Proteinase von Golubkov, Vladislav S., Cieplak, Piotr, Chekanov, Alexei V., Ratnikov, Boris I., Aleshin, Alexander E., Golubkova, Natalya V., Postnova, Tatiana I., Radichev, Ilian A., Rozanov, Dmitri V., Zhu, Wenhong, Motamedchaboki, Khatereh, Strongin, Alex Y.

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Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase von Stanford, Stephanie M, Aleshin, Alexander E, Zhang, Vida, Ardecky, Robert J, Hedrick, Michael P, Zou, Jiwen, Ganji, Santhi R, Bliss, Matthew R, Yamamoto, Fusayo, Bobkov, Andrey A, Kiselar, Janna, Liu, Yingge, Cadwell, Gregory W, Khare, Shilpi, Yu, Jinghua, Barquilla, Antonio, Chung, Thomas D Y, Mustelin, Tomas, Schenk, Simon, Bankston, Laurie A, Liddington, Robert C, Pinkerton, Anthony B, Bottini, Nunzio

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Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus von Shiryaev, Sergey A, Radichev, Ilian A, Ratnikov, Boris I, Aleshin, Alexander E, Gawlik, Katarzyna, Stec, Boguslaw, Frisch, Christian, Knappik, Achim, Strongin, Alex Y

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Vaccinia virus N1L protein resembles a B cell lymphoma‐2 (Bcl‐2) family protein von Aoyagi, Mika, Zhai, Dayong, Jin, Chaofang, Aleshin, Alexander E., Stec, Boguslaw, Reed, John C., Liddington, Robert C.

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Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase: IMPLICATIONS IN CANCER AND EMBRYOGEN... von Golubkov, Vladislav S, Chekanov, Alexei V, Cieplak, Piotr, Aleshin, Alexander E, Chernov, Andrei V, Zhu, Wenhong, Radichev, Ilian A, Zhang, Danhua, Dong, P. Duc, Strongin, Alex Y

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