Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma von Simpson, Aaron D., Soo, Ying Wei Jenetta, Rieunier, Guillaume, Aleksic, Tamara, Ansorge, Olaf, Jones, Chris, Macaulay, Valentine M.

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Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage von Aleksic, Tamara, Gray, Nicki, Wu, Xiaoning, Rieunier, Guillaume, Osher, Eliot, Mills, Jack, Verrill, Clare, Bryant, Richard J, Han, Cheng, Hutchinson, Kathryn, Lambert, Adam G, Kumar, Rajeev, Hamdy, Freddie C, Weyer-Czernilofsky, Ulrike, Sanderson, Michael P, Bogenrieder, Thomas, Taylor, Stephen, Macaulay, Valentine M

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Rediscovery of Euxinopetalum dobatorum Hoffman, 1973 (Diplopoda, Callipodida, Schizopetalidae) in Turkey von Antić, Dragan, Aleksić, Tamara, Milovanović, Jelena, Elverici, Mert

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Type 1 Insulin-like Growth Factor Receptor Translocates to the Nucleus of Human Tumor Cells von ALEKSIC, Tamara, CHITNIS, Meenali M, PERESTENKO, Olga V, SHAN GAO, THOMAS, Peter H, TURNER, Gareth D, PROTHEROE, Andrew S, HOWARTH, Mark, MACAULAY, Valentine M

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Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo von Baumann, Bernd, Wagner, Martin, Aleksic, Tamara, von Wichert, Götz, Weber, Christoph K, Adler, Guido, Wirth, Thomas

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Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling von Gao, Shan, Bajrami, Ilirjana, Verrill, Clare, Kigozi, Asha, Ouaret, Djamila, Aleksic, Tamara, Asher, Ruth, Han, Cheng, Allen, Paul, Bailey, Deborah, Feller, Stephan, Kashima, Takeshi, Athanasou, Nicholas, Blay, Jean-Yves, Schmitz, Sandra, Machiels, Jean-Pascal, Upile, Nav, Jones, Terry M, Thalmann, George, Ashraf, Shazad Q, Wilding, Jennifer L, Bodmer, Walter F, Middleton, Mark R, Ashworth, Alan, Lord, Christopher J, Macaulay, Valentine M

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Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells von Aleksic, Tamara, Feller, Stephan M

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Can we unlock the potential of IGF-1R inhibition in cancer therapy? von King, Helen, Aleksic, Tamara, Haluska, Paul, Macaulay, Valentine M

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IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination von Chitnis, M M, Lodhia, K A, Aleksic, T, Gao, S, Protheroe, A S, Macaulay, V M

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IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer von Aleksic, Tamara, Verrill, Clare, Bryant, Richard J, Han, Cheng, Worrall, Andrew Ross, Brureau, Laurent, Larré, Stephane, Higgins, Geoff S, Fazal, Fahad, Sabbagh, Ahmad, Haider, Syed, Buffa, Francesca M, Cole, David, Macaulay, Valentine M

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Suppression of homologous recombination sensitizes human tumor cells to IGF‐1R inhibition von Lodhia, Kunal A., Gao, Shan, Aleksic, Tamara, Esashi, Fumiko, Macaulay, Valentine M.

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IGF-1R expression is associated with HPV-negative status and adverse survival in head and neck squamous cell cancer von Dale, Oliver T, Aleksic, Tamara, Shah, Ketan A, Han, Cheng, Mehanna, Hisham, Rapozo, Davy C M, Sheard, Jon D H, Goodyear, Paul, Upile, Navdeep S, Robinson, Max, Jones, Terence M, Winter, Stuart, Macaulay, Valentine M

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Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling von Qureishi, Ali, Rieunier, Guillaume, Shah, Ketan A., Aleksic, Tamara, Winter, Stuart C., Møller, Henrik, Macaulay, Valentine M.

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Nuclear IGF-1R interacts with regulatory regions of chromatin to promote RNA polymerase II recruitment and gene expression associated with advanced tumor stage von Aleksic, Tamara, Gray, Nicki, Wu, Xiaoning, Rieunier, Guillaume, Osher, Eliot, Mills, Jack, Verrill, Clare, Bryant, Richard J., Han, Cheng, Hutchinson, Kathryn, Lambert, Adam G., Kumar, Rajeev, Hamdy, Freddie C., Weyer-Czernilofsky, Ulrike, Sanderson, Michael P., Bogenrieder, Thomas, Taylor, Stephen, Macaulay, Valentine M.

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Durable Response of Spinal Chordoma to Combined Inhibition of IGF-1R and EGFR von Aleksic, Tamara, Browning, Lisa, Woodward, Martha, Phillips, Rachel, Page, Suzanne, Henderson, Shirley, Athanasou, Nicholas, Ansorge, Olaf, Whitwell, Duncan, Pratap, Sarah, Hassan, A Bassim, Middleton, Mark R, Macaulay, Valentine M

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IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide von Ramcharan, Roger, Aleksic, Tamara, Kamdoum, Wilfride Petnga, Gao, Shan, Pfister, Sophia X, Tanner, Jordan, Bridges, Esther, Asher, Ruth, Watson, Amanda J, Margison, Geoffrey P, Woodcock, Mick, Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R, Macaulay, Valentine M

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Cellular immune reaction in the pancreas is induced by constitutively active IκB kinase-2 von Aleksic, Tamara, Baumann, Bernd, Wagner, Martin, Adler, Guido, Wirth, Thomas, Weber, Christoph K

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Abstract 1741: Inhibition of type 1 insulin-like growth factor receptor (IGF-1R) influences processing of replication-associated DNA double-strand breaks (DSBs) and induces schedul... von Ramcharan, Roger N., Aleksic, Tamara, Gao, Shan, Tanner, Jordan, Darvill, Nicholas, Bridges, Esther, Asher, Ruth, Watson, Amanda J., Margison, Geoffrey P., Repapi, Emmanouela, Li, Ji-Liang, Middleton, Mark R., Macaulay, Valentine M.

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The cAMP/Epac1/Rap1 pathway in pancreatic carcinoma von Lorenz, Richard, Aleksic, Tamara, Wagner, Martin, Adler, Guido, Weber, Christoph K

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Type 1 IGF receptor translocates to the nucleus of human tumor cells von Aleksic, Tamara, Chitnis, Meenali M., Perestenko, Olga V., Gao, Shan, Thomas, Peter H., Turner, Gareth D., Protheroe, Andrew S., Howarth, Mark, Macaulay, Valentine M.

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