A Call for Systematic Research on Solute Carriers von César-Razquin, Adrián, Snijder, Berend, Frappier-Brinton, Tristan, Isserlin, Ruth, Gyimesi, Gergely, Bai, Xiaoyun, Reithmeier, Reinhart A., Hepworth, David, Hediger, Matthias A., Edwards, Aled M., Superti-Furga, Giulio

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Structure and Biochemical Functions of SIRT6 von Pan, Patricia W., Feldman, Jessica L., Devries, Mark K., Dong, Aiping, Edwards, Aled M., Denu, John M.

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Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states von Shintre, Chitra A., Pike, Ashley C. W., Li, Qiuhong, Kim, Jung-In, Barr, Alastair J., Goubin, Solenne, Shrestha, Leela, Yang, Jing, Berridge, Georgina, Ross, Jonathan, Stansfeld, Phillip J., Sansom, Mark S. P., Edwards, Aled M., Bountra, Chas, Marsden, Brian D., von Delft, Frank, Bullock, Alex N., Gileadi, Opher, Burgess-Brown, Nicola A., Carpenter, Elisabeth P.

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Bacteriophage HK97 gp15 Moron Element Encodes a Novel Superinfection Exclusion Protein von Cumby, Nichole, Edwards, Aled M, Davidson, Alan R, Maxwell, Karen L

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A data science roadmap for open science organizations engaged in early-stage drug discovery von Edfeldt, Kristina, Edwards, Aled M., Engkvist, Ola, Günther, Judith, Hartley, Matthew, Hulcoop, David G., Leach, Andrew R., Marsden, Brian D., Menge, Amelie, Misquitta, Leonie, Müller, Susanne, Owen, Dafydd R., Schütt, Kristof T., Skelton, Nicholas, Steffen, Andreas, Tropsha, Alexander, Vernet, Erik, Wang, Yanli, Wellnitz, James, Willson, Timothy M., Clevert, Djork-Arné, Haibe-Kains, Benjamin, Schiavone, Lovisa Holmberg, Schapira, Matthieu

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Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications von Ayoubi, Riham, Ryan, Joel, Biddle, Michael S, Alshafie, Walaa, Fotouhi, Maryam, Bolivar, Sara Gonzalez, Ruiz Moleon, Vera, Eckmann, Peter, Worrall, Donovan, McDowell, Ian, Southern, Kathleen, Reintsch, Wolfgang, Durcan, Thomas M, Brown, Claire, Bandrowski, Anita, Virk, Harvinder, Edwards, Aled M, McPherson, Peter, Laflamme, Carl

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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72 von Laflamme, Carl, McKeever, Paul M, Kumar, Rahul, Schwartz, Julie, Kolahdouzan, Mahshad, Chen, Carol X, You, Zhipeng, Benaliouad, Faiza, Gileadi, Opher, McBride, Heidi M, Durcan, Thomas M, Edwards, Aled M, Healy, Luke M, Robertson, Janice, McPherson, Peter S

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The Biology/Disease-driven Human Proteome Project (B/D-HPP): Enabling Protein Research for the Life Sciences Community von Aebersold, Ruedi, Bader, Gary D, Edwards, Aled M, van Eyk, Jennifer E, Kussmann, Martin, Qin, Jun, Omenn, Gilbert S

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Hepatic Gene Expression Discriminates Responders and Nonresponders in Treatment of Chronic Hepatitis C Viral Infection von Chen, Limin, Borozan, Ivan, Feld, Jordan, Sun, Jing, Tannis, Laura-Lee, Coltescu, Catalina, Heathcote, Jenny, Edwards, Aled M., McGilvray, Ian D.

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Chemical Screening Methods to Identify Ligands That Promote Protein Stability, Protein Crystallization, and Structure Determination von Vedadi, Masoud, Niesen, Frank H., Allali-Hassani, Abdellah, Fedorov, Oleg Y., Finerty, Patrick J., Wasney, Gregory A., Yeung, Ron, Arrowsmith, Cheryl, Ball, Linda J., Berglund, Helena, Hui, Raymond, Marsden, Brian D., Nordlund, Pär, Sundstrom, Michael, Weigelt, Johan, Edwards, Aled M.

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A Novel Family of Sequence-specific Endoribonucleases Associated with the Clustered Regularly Interspaced Short Palindromic Repeats von Beloglazova, Natalia, Brown, Greg, Zimmerman, Matthew D., Proudfoot, Michael, Makarova, Kira S., Kudritska, Marina, Kochinyan, Samvel, Wang, Shuren, Chruszcz, Maksymilian, Minor, Wladek, Koonin, Eugene V., Edwards, Aled M., Savchenko, Alexei, Yakunin, Alexander F.

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Structural and chemical profiling of the human cytosolic sulfotransferases von Allali-Hassani, Abdellah, Pan, Patricia W, Dombrovski, Ludmila, Najmanovich, Rafael, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thornton, Janet, Thonton, Janet, Edwards, Aled M, Bochkarev, Alexey, Plotnikov, Alexander N, Vedadi, Masoud, Arrowsmith, Cheryl H

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Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins von Zhong, Nan, Loppnau, Peter, Seitova, Alma, Ravichandran, Mani, Fenner, Maria, Jain, Harshika, Bhattacharya, Anandi, Hutchinson, Ashley, Paduch, Marcin, Lu, Vincent, Olszewski, Michal, Kossiakoff, Anthony A, Dowdell, Evan, Koide, Akiko, Koide, Shohei, Huang, Haiming, Nadeem, Vincent, Sidhu, Sachdev S, Greenblatt, Jack F, Marcon, Edyta, Arrowsmith, Cheryl H, Edwards, Aled M, Gräslund, Susanne

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The Structural Basis of ZMPSTE24-Dependent Laminopathies von Quigley, Andrew, Dong, Yin Yao, Pike, Ashley C. W., Dong, Liang, Shrestha, Leela, Berridge, Georgina, Stansfeld, Phillip J., Sansom, Mark S. P., Edwards, Aled M., Bountra, Chas, von Delft, Frank, Bullock, Alex N., Burgess-Brown, Nicola A., Carpenter, Elisabeth P.

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Genome-wide Analysis of Substrate Specificities of the Escherichia coli Haloacid Dehalogenase-like Phosphatase Family von Kuznetsova, Ekaterina, Proudfoot, Michael, Gonzalez, Claudio F., Brown, Greg, Omelchenko, Marina V., Borozan, Ivan, Carmel, Liran, Wolf, Yuri I., Mori, Hirotada, Savchenko, Alexei V., Arrowsmith, Cheryl H., Koonin, Eugene V., Edwards, Aled M., Yakunin, Alexander F.

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In situ proteolysis for protein crystallization and structure determination von Dong, Aiping, Xu, Xiaohui, Edwards, Aled M

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Stopping pandemics before they start: Lessons learned from SARS-CoV-2 von Edwards, Aled M, Baric, Ralph S, Saphire, Erica Ollmann, Ulmer, Jeffrey B

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Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria von Nocek, Boguslaw, Kochinyan, Samvel, Proudfoot, Michael, Brown, Greg, Evdokimova, Elena, Osipiuk, Jerzy, Edwards, Aled M, Savchenko, Alexei, Joachimiak, Andrzej, Yakunin, Alexander F

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Silencing of USP18 Potentiates the Antiviral Activity of Interferon Against Hepatitis C Virus Infection von Randall, Glenn, Chen, Limin, Panis, Maryline, Fischer, Andrew K., Lindenbach, Brett D., Sun, Jing, Heathcote, Jenny, Rice, Charles M., Edwards, Aled M., McGilvray, Ian D.

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A guide to selecting high-performing antibodies for Huntingtin (UniProt ID: P42858) for use in western blot, immunoprecipitation, and immunofluorescence [version 1; peer review: aw... von Fanti, Rebeka, Ayoubi, Riham, Alende, Charles, Fotouhi, Maryam, González Bolívar, Sara, Chandrasekaran, Renu, Southern, Kathleen, Edwards, Aled M., Harding, Rachel J., Laflamme, Carl

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