CENPA overexpression promotes genome instability in pRb-depleted human cells von Amato, Angela, Schillaci, Tiziana, Lentini, Laura, Di Leonardo, Aldo

Volltext

A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19 von Spinelli, Gaetano, Biddeci, Giuseppa, Artale, Anna, Valentino, Francesca, Tarantino, Giuseppe, Gallo, Giuseppe, Gianguzza, Fabrizio, Conaldi, Pier Giulio, Corrao, Salvatore, Gervasi, Francesco, Aronica, Tommaso Silvano, Di Leonardo, Aldo, Duro, Giovanni, Di Blasi, Francesco

Volltext

RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts von Iovino, Flora, Lentini, Laura, Amato, Angela, Di Leonardo, Aldo

Volltext

Targeting Nonsense: Optimization of 1,2,4-Oxadiazole TRIDs to Rescue CFTR Expression and Functionality in Cystic Fibrosis Cell Model Systems von Pibiri, Ivana, Melfi, Raffaella, Tutone, Marco, Di Leonardo, Aldo, Pace, Andrea, Lentini, Laura

Volltext

Site-Specific RNA Editing of Stop Mutations in the CFTR mRNA of Human Bronchial Cultured Cells von Chiavetta, Roberta F, Titoli, Simona, Barra, Viviana, Cancemi, Patrizia, Melfi, Raffaella, Di Leonardo, Aldo

Volltext

Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons von Melfi, Raffaella, Cancemi, Patrizia, Chiavetta, Roberta, Barra, Viviana, Lentini, Laura, Di Leonardo, Aldo

Volltext

Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells von Barra, Viviana, Schillaci, Tiziana, Lentini, Laura, Costa, Giuseppe, Di Leonardo, Aldo

Volltext

Strategies against Nonsense: Oxadiazoles as Translational Readthrough-Inducing Drugs (TRIDs) von Campofelice, Ambra, Lentini, Laura, Di Leonardo, Aldo, Melfi, Raffaella, Tutone, Marco, Pace, Andrea, Pibiri, Ivana

Volltext

Investigating the Inhibition of FTSJ1, a Tryptophan tRNA-Specific 2'-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR von Carollo, Pietro Salvatore, Tutone, Marco, Culletta, Giulia, Fiduccia, Ignazio, Corrao, Federica, Pibiri, Ivana, Di Leonardo, Aldo, Zizzo, Maria Grazia, Melfi, Raffaella, Pace, Andrea, Almerico, Anna Maria, Lentini, Laura

Volltext

Nonsense codons suppression. An acute toxicity study of three optimized TRIDs in murine model, safety and tolerability evaluation von Corrao, Federica, Zizzo, Maria Grazia, Tutone, Marco, Melfi, Raffaella, Fiduccia, Ignazio, Carollo, Pietro Salvatore, Leonardo, Aldo Di, Caldara, Gaetano, Perriera, Riccardo, Pace, Andrea, Belmonte, Beatrice, Sammataro, Selene, Pibiri, Ivana, Lentini, Laura

Volltext

P14ARF: The Absence that Makes the Difference von Cilluffo, Danilo, Barra, Viviana, Di Leonardo, Aldo

Volltext

NOTCH3 expression is linked to breast cancer seeding and distant metastasis von Leontovich, Alexey A, Jalalirad, Mohammad, Salisbury, Jeffrey L, Mills, Lisa, Haddox, Candace, Schroeder, Mark, Tuma, Ann, Guicciardi, Maria E, Zammataro, Luca, Gambino, Mario W, Amato, Angela, Di Leonardo, Aldo, McCubrey, James, Lange, Carol A, Liu, Minetta, Haddad, Tufia, Goetz, Matthew, Boughey, Judy, Sarkaria, Jann, Wang, Liewei, Ingle, James N, Galanis, Evanthia, D'Assoro, Antonino B

Volltext

Specific Irreversible Cell-Cycle Arrest and Depletion of Cancer Cells Obtained by Combining Curcumin and the Flavonoids Quercetin and Fisetin von Barra, Viviana, Chiavetta, Roberta Flavia, Titoli, Simona, Provenzano, Ivana Maria, Carollo, Pietro Salvatore, Di Leonardo, Aldo

Volltext

Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay von Lentini, Laura, Melfi, Raffaella, Di Leonardo, Aldo, Spinello, Angelo, Barone, Giampaolo, Pace, Andrea, Palumbo Piccionello, Antonio, Pibiri, Ivana

Volltext

Proliferation of aneuploid cells induced by CENP-E depletion is counteracted by the p14ARF tumor suppressor von Veneziano, Lorena, Barra, Viviana, Cilluffo, Danilo, Di Leonardo, Aldo

Volltext

MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a P53 pathway preventing aneuploid cells propagation von Lentini, Laura, Barra, Viviana, Schillaci, Tiziana, Di Leonardo, Aldo

Volltext

Transcriptomic Changes Following Partial Depletion of CENP-E in Normal Human Fibroblasts von Cilluffo, Danilo, Chiavetta, Roberta Flavia, Bivona, Serena, Contino, Flavia, Coronnello, Claudia, Feo, Salvatore, Di Leonardo, Aldo, Barra, Viviana

Volltext

Caffeine boosts Ataluren's readthrough activity von Lentini, Laura, Melfi, Raffaella, Cancemi, Patrizia, Pibiri, Ivana, Di Leonardo, Aldo

Volltext

Functional Inactivation of pRB Results in Aneuploid Mammalian Cells After Release From a Mitotic Block von Lentini, Laura, Pipitone, Loredana, Di Leonardo, Aldo

Volltext

Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype von Lentini, Laura, Amato, Angela, Schillaci, Tiziana, Di Leonardo, Aldo

Volltext