Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells von Borroto, Aldo, Alarcón, Balbino, Navarro, María N

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A non-conserved amino acid variant regulates differential signalling between human and mouse CD28 von Porciello, Nicla, Grazioli, Paola, Campese, Antonio F., Kunkl, Martina, Caristi, Silvana, Mastrogiovanni, Marta, Muscolini, Michela, Spadaro, Francesca, Favre, Cédric, Nunès, Jacques A., Borroto, Aldo, Alarcon, Balbino, Screpanti, Isabella, Tuosto, Loretta

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Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses von Cruz-Adalia, Aránzazu, Ramirez-Santiago, Guillermo, Osuna-Pérez, Jesús, Torres-Torresano, Mónica, Zorita, Virgina, Martínez-Riaño, Ana, Boccasavia, Viola, Borroto, Aldo, Martínez del Hoyo, Gloria, González-Granado, José María, Alarcón, Balbino, Sánchez-Madrid, Francisco, Veiga, Esteban

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Aurora A drives early signalling and vesicle dynamics during T-cell activation von Blas-Rus, Noelia, Bustos-Morán, Eugenio, Pérez de Castro, Ignacio, de Cárcer, Guillermo, Borroto, Aldo, Camafeita, Emilio, Jorge, Inmaculada, Vázquez, Jesús, Alarcón, Balbino, Malumbres, Marcos, Martín-Cófreces, Noa B., Sánchez-Madrid, Francisco

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Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction von Alarcon, Balbino, Borroto, Aldo

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Human T-cell receptor triggering requires inactivation of Lim kinase-1 by Slingshot-1 phosphatase von Gómez-Morón, Álvaro, Alegre-Gómez, Sergio, Ramirez-Muñoz, Rocio, Hernaiz-Esteban, Alicia, Carrasco-Padilla, Carlos, Scagnetti, Camila, Aguilar-Sopeña, Óscar, García-Gil, Marta, Borroto, Aldo, Torres-Ruiz, Raul, Rodriguez-Perales, Sandra, Sánchez-Madrid, Francisco, Martín-Cófreces, Noa Beatriz, Roda-Navarro, Pedro

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Author Correction: Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses von Cruz-Adalia, Aránzazu, Ramirez-Santiago, Guillermo, Osuna-Pérez, Jesús, Torres-Torresano, Mónica, Zorita, Virgina, Martínez-Riaño, Ana, Boccasavia, Viola, Borroto, Aldo, Martínez del Hoyo, Gloria, González-Granado, José María, Alarcón, Balbino, Sánchez-Madrid, Francisco, Veiga, Esteban

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CD3ε recruits Numb to promote TCR degradation von Martin-Blanco, Nadia, Jiménez Teja, Daniel, Bretones, Gabriel, Borroto, Aldo, Caraballo, Michael, Screpanti, Isabella, León, Javier, Alarcón, Balbino, Canelles, Matilde

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Conformational changes in the T cell receptor differentially determine T cell subset development in mice von Blanco, Raquel, Borroto, Aldo, Schamel, Wolfgang, Pereira, Pablo, Alarcon, Balbino

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Triggering the TCR Complex Causes the Downregulation of Nonengaged Receptors by a Signal Transduction-Dependent Mechanism von José, Ester San, Borroto, Aldo, Niedergang, Florence, Alcover, Andrés, Alarcón, Balbino

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Protein Ectodomain Shedding von Arribas, Joaquín, Borroto, Aldo

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A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation von Swamy, Mahima, Beck-Garcia, Katharina, Beck-Garcia, Esmeralda, Hartl, Frederike A., Morath, Anna, Yousefi, O. Sascha, Dopfer, Elaine Pashupati, Molnár, Eszter, Schulze, Anna K., Blanco, Raquel, Borroto, Aldo, Martín-Blanco, Nadia, Alarcon, Balbino, Höfer, Thomas, Minguet, Susana, Schamel, Wolfgang W.A.

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SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation von Rueda-Carrasco, Javier, Martin-Bermejo, María Jesús, Pereyra, Guadalupe, Mateo, María Inés, Borroto, Aldo, Brosseron, Frederic, Kummer, Markus P, Schwartz, Stephanie, López-Atalaya, José P, Alarcon, Balbino, Esteve, Pilar, Heneka, Michael T, Bovolenta, Paola

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367 - Impacts of TCR-Nck Interaction Inhibitors on T Cell Activation Driven By Mixed Lymphocyte Reactions von Dwyer, Shannon, Borroto, Aldo, Gagete, Andres, Alarcon, Balbino, VanDeusen, Chris

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Impacts of TCR-Nck Interaction Inhibitors on T Cell Activation Driven By Mixed Lymphocyte Reactions von Dwyer, Shannon, Borroto, Aldo, Gagete, Andres, Alarcon, Balbino, VanDeusen, Chris

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Crammed signaling motifs in the T-cell receptor von Borroto, Aldo, Abia, David, Alarcón, Balbino

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Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen von Boccasavia, Viola L., Bovolenta, Elena R., Villanueva, Ana, Borroto, Aldo, Oeste, Clara L., van Santen, Hisse M., Prieto, Cristina, Alonso-López, Diego, Diaz-Muñoz, Manuel D., Batista, Facundo D., Alarcón, Balbino

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Characterization of the Region Involved in CD3 Pairwise Interactions within the T Cell Receptor Complex von Borroto, Aldo, Mallabiabarrena, Arrate, Albar, Juan P., MartıÖnez-A., Carlos, AlarcoÖn, Balbino

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Relevance of Nck-CD3 epsilon interaction for T cell activation in vivo von Borroto, Aldo, Arellano, Irene, Blanco, Raquel, Fuentes, Manuel, Orfao, Alberto, Dopfer, Elaine P, Prouza, Marek, Suchànek, Miloslav, Schamel, Wolfgang W, Alarcón, Balbino

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Long-Term Effect of the TCR-Nck Interaction Inhibitor AX-024 on GvHD in a Human Xenogeneic Model von Borroto, Aldo, Reyes-Garau, Diana, Gagete, Andres, Dwyer, Shannon, VanDeusen, Chris, Alarcon, Balbino

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