Analyzing biomarkers of cancer immunotherapy (CIT) response using a real-world clinico-genomic database von Singal, G., Miller, P.G., Agarwala, V., Li, G., Gossai, A., Albacker, L.A., Goldberg, M.E., He, J., Frank, S., Bourque, D., Ivanov, I., Fabrizio, D., Caron, T., Parker, A., Guria, A., Miller, V.A., Elvin, J.A., Ross, J.S., Abernethy, A., Stephens, P.J.

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1487MO A pan-sarcoma investigation of genetic alterations associated with high telomeric content von Sharaf, R., Jin, D.X., Grady, J., Frampton, G.M., Albacker, L.A., Thomas, D., Montesion, M.

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893P Clinico-genetic profiling of HRAS mutant head and neck squamous cell carcinoma (HNSCC) von Le, X., Marcelo, K., Coleman, N., Hopkins, J., Balsara, B., Leoni, M., Spelman, A.R., Hong, D.S., Albacker, L.A., Gillison, M.

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Identification of genomic markers of sensitivity and resistance to checkpoint inhibitors in non-small cell lung cancer in a real world clinico-genomic database von Murugesan, K., Li, G., Kaushik, G., Singal, G., Miller, V.A., Frampton, G.M., Albacker, L.A.

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677PD - Comprehensive genomic profiling (CGP) of mixed hepatocellular cholangiocarcinomas (cHCC-CCA) von Murugesan, K., Javle, M., Schrock, A.B., Ngo, N., Frampton, G.M., Alexander, B.M., Miller, V.A., Bekaii-Saab, T., Albacker, L.A., Ross, J.S., Ali, S.M.

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Comprehensive genomic profiling (CGP) of mixed hepatocellular cholangiocarcinomas (cHCC-CCA) von Murugesan, K., Javle, M., Schrock, A.B., Ngo, N., Frampton, G.M., Alexander, B.M., Miller, V.A., Bekaii-Saab, T., Albacker, L.A., Ross, J.S., Ali, S.M.

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Pan-squamous genomic profiling stratified by anatomic tumor site and viral association von Montesion, M., Chung, C.H., Sokol, E.S., Khan, S.A., Kang, H., Albacker, L.A., Johnson, J.M., Frampton, G.M., Miller, V.A., Ross, J.S., Ali, S.M.

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580P TALAPRO-1: Talazoparib (TALA) monotherapy in metastatic castration-resistant prostate cancer (mCRPC) with DNA damage response alterations (DDRm) - Exploration of non-DDR mutat... von Mehra, N., de Bono, J., Laird, A.D., Barthélémy, P., Delva, R., Dorff, T., Maruzzo, M., Stirling, A., Machiels, J-P., Dumez, H., Renard, V., Hopkins, J., Albacker, L.A., Chen, H-C., Healy, C., Chelliserry, J., van Oort, I.M., Scagliotti, G., Fizazi, K.

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314P - Next-generation DNA sequencing (NGS) results for tumours from phase II ABRAZO study of talazoparib after platinum or cytotoxic non-platinum regimens in patients (pts) with a... von Turner, N.C., Laird, A.D., Telli, M.L., Rugo, H.S., Mailliez, A., Ettl, J., Grischke, E.-M., Mina, L.A., Balmaña, J., Fasching, P.A., Hurvitz, S.A., Albacker, L.A., Frampton, G.M., Chelliserry, J., Bycott, P., Conte, U., Wardley, A.M., Robson, M.E.

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Next-generation DNA sequencing (NGS) results for tumours from phase II ABRAZO study of talazoparib after platinum or cytotoxic non-platinum regimens in patients (pts) with advanced... von Turner, N.C., Laird, A.D., Telli, M.L., Rugo, H.S., Mailliez, A., Ettl, J., Grischke, E.-M., Mina, L.A., Balmaña, J., Fasching, P.A., Hurvitz, S.A., Albacker, L.A., Frampton, G.M., Chelliserry, J., Bycott, P., Conte, U., Wardley, A.M., Robson, M.E.

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Kinase fusions in colorectal cancers: A unique biologic subset von Madison, R, Pietrantonio, F, Juckett, L, Cremolini, C, Chung, J, Albacker, L A, Miller, V A, Klempner, S J, Resnick, M B, Yakirevich, E, Ou, S-H I, Fakih, M, Schrock, A B, Ross, J S, Ali, S M

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138P TALAPRO-1: Talazoparib (TALA) monotherapy in men with DNA damage response alterations (DDRalt) and metastatic castration-resistant prostate cancer (mCRPC): Exploration of DDRa... von Mehra, N., Fizazi, K., Laird, A.D., Barthélémy, P., Delva, R., Dorff, T., Maruzzo, M., Stirling, A., Machiels, J-P., Dumez, H., Renard, V., Albacker, L.A., Hopkins, J., Chen, H-C., Mata, M., Di Santo, N., Healy, C.G., van Oort, I.M., Buttigliero, C., de Bono, J.S.

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PIK3CA alterations in metastatic breast cancer (mBC) von Albanell, J., Casadevall, D., Sokol, E.S., Albacker, L.A., Elvin, J.A., Vergilio, J.-A., Killian, J.K., Ngo, N., Lin, D., Ramkissoon, S., Severson, E., Ali, S.M., Schrock, A.B., Chung, J., Reddy, P., Miller, V.A., Alexander, B.M., McGregor, K., Ross, J.S., Leyland-Jones, B.

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306PD - PIK3CA alterations in metastatic breast cancer (mBC) von Albanell, J., Casadevall, D., Sokol, E.S., Albacker, L.A., Elvin, J.A., Vergilio, J.-A., Killian, J.K., Ngo, N., Lin, D., Ramkissoon, S., Severson, E., Ali, S.M., Schrock, A.B., Chung, J., Reddy, P., Miller, V.A., Alexander, B.M., McGregor, K., Ross, J.S., Leyland-Jones, B.

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Immune checkpoint inhibitor (ICPI) efficacy and resistance detected by comprehensive genomic profiling (CGP) in non-small cell lung cancer (NSCLC) von Ross, J.S., Goldberg, M.E., Albacker, L.A., Gay, L.M., Agarwala, V., Elvin, J.A., Vergilio, J-A., Suh, J., Ramkissoon, S., Severson, E., Daniel, S., Ali, S.M., Schrock, A.B., Frampton, G.M., Fabrizio, D., Miller, V.A., Singal, G., Abernethy, A., Stephens, P.J.

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