Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR von Chen, Ximin, Chen, Laurence C, Khericha, Mobina, Meng, Xiangzhi, Salvestrini, Emma, Shafer, Amanda, Iyer, Neha, Alag, Anya S, Ding, Yunfeng, Nicolaou, Demetri M, Chen, Yvonne Y

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Rational protein design yields a CD20 CAR with superior antitumor efficacy compared to CD19 CAR von Chen, Ximin, Chen, Laurence C., Khericha, Mobina, Meng, Xiangzhi, Salvestrini, Emma, Shafer, Amanda, Iyer, Neha, Alag, Anya S., Ding, Yunfeng, Nicolaou, Demetri M., Chen, Yvonne Y.

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Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune Evasion von Heitzeneder, Sabine, Sotillo, Elena, Shern, Jack F, Sindiri, Sivasish, Xu, Peng, Jones, Robert, Pollak, Michael, Noer, Pernille R, Lorette, Julie, Fazli, Ladan, Alag, Anya, Meltzer, Paul, Lau, Ching, Conover, Cheryl A, Oxvig, Claus, Sorensen, Poul H, Maris, John M, Khan, Javed, Mackall, Crystal L

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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity von Heitzeneder, Sabine, Bosse, Kristopher R., Zhu, Zhongyu, Zhelev, Doncho, Majzner, Robbie G., Radosevich, Molly T., Dhingra, Shaurya, Sotillo, Elena, Buongervino, Samantha, Pascual-Pasto, Guillem, Garrigan, Emily, Xu, Peng, Huang, Jing, Salzer, Benjamin, Delaidelli, Alberto, Raman, Swetha, Cui, Hong, Martinez, Benjamin, Bornheimer, Scott J., Sahaf, Bita, Alag, Anya, Fetahu, Irfete S., Hasselblatt, Martin, Parker, Kevin R., Anbunathan, Hima, Hwang, Jennifer, Huang, Min, Sakamoto, Kathleen, Lacayo, Norman J., Klysz, Dorota D., Theruvath, Johanna, Vilches-Moure, José G., Satpathy, Ansuman T., Chang, Howard Y., Lehner, Manfred, Taschner-Mandl, Sabine, Julien, Jean-Phillipe, Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L.

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Novel Cluster AZ Arthrobacter phages Powerpuff, Lego, and YesChef exhibit close functional relationships with Microbacterium phages von Kapinos, Andrew, Aghamalian, Pauline, Capehart, Erika, Alag, Anya, Angel, Heather, Briseno, Eddie, Corado Perez, Byron, Farag, Emily, Foster, Hilory, Hakim, Abbas, Hernandez-Casas, Daisy, Huang, Calvin, Lam, Derek, Mendez, Maya, Min, Ashley, Nguyen, Nikki, Omholt, Alexa L, Ortiz, Emily, Saldivar, Lizbeth Shelly, Shannon, Jack Arthur, Smith, Rachel, Sridhar, Mihika V, Ta, An, Theophilus, Malavika C, Ngo, Ryan, Torres, Canela, Reddi, Krisanavane, Freise, Amanda C, Moberg Parker, Jordan

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Abstract A09: Glypican-2 targeted CAR T cells designed to effectively eradicate endogenous site density solid tumors in the absence of toxicity von Heitzeneder, Sabine, Bosse, Kristopher R., Zhu, Zhongyu, Majzner, Robbie G., Theruvath, Johanna, Xu, Peng, Dhingra, Shaurya, Anbunathan, Hima, Alag, Anya, Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L.

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Abstract 1548: Potent activity of CAR T cells targeting the oncofetal protein GPC2 engineered to recognize low antigen density in neuroblastoma von Heitzeneder, Sabine, Bosse, Kristopher R., Zhu, Zhongyu, Jelev, Dontcho, Dhingra, Shaurya, Majzner, Robbie, Sotillo-Pineiro, Elena, Buongervino, Samantha, Xu, Peng, Huang, Jing, Delaidelli, Alberto, Hasselblatt, Martin, Parker, Kevin, Anbunathan, Hima, Alag, Anya, Hwang, Jennifer, Huang, Min, Klysz, Dorota D., Theruvath, Johanna L., Vilches-Moure, Jose G., Satpathy, Ansuman T., Sorensen, Poul H., Dimitrov, Dimiter S., Maris, John M., Mackall, Crystal L.

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