S191: CALRETICULIN‐MUTATED HEMATOPOIETIC CELLS ARE VULNERABLE TO THE COMBINED INHIBITION OF THE PROTEASOME AND THE IRE1A‐XBP1 AXIS OF THE UNFOLDED PROTEIN RESPONSE von Jutzi, J. S., Marneth, A. E., Jimenez‐Santos, M. J., Guerra‐Moreno, A., Myers, S. A., Carr, S. A., Galen, P., Al‐Shahrour, F., Nam, A. S., Mullally, A.

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The correlation between immune subtypes and consensus molecular subtypes in colorectal cancer identifies novel tumour microenvironment profiles, with prognostic and therapeutic imp... von Soldevilla, B., Carretero-Puche, C., Gomez-Lopez, G., Al-Shahrour, F., Riesco, M.C., Gil-Calderon, B., Alvarez-Vallina, L., Espinosa-Olarte, P., Gomez-Esteves, G., Rubio-Cuesta, B., Sarmentero, J., La Salvia, A., Garcia-Carbonero, R.

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BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments von Al-Shahrour, Fátima, Minguez, Pablo, Vaquerizas, Juan M., Conde, Lucía, Dopazo, Joaquín

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High burden of copy number alterations and c-MYC amplification in prostate cancer from BRCA2 germline mutation carriers von Castro, E., Jugurnauth-Little, S., Karlsson, Q., Al-Shahrour, F., Piñeiro-Yañez, E., Van de Poll, F., Leongamornlert, D., Dadaev, T., Govindasami, K., Guy, M., Eeles, R., Kote-Jarai, Z.

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Discovering molecular functions significantly related to phenotypes by combining gene expression data and biological information von Al-Shahrour, Fátima, Díaz-Uriarte, Ramón, Dopazo, Joaquín

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Somatic BRCA2 bi-allelic loss in the primary prostate cancer was associated to objective response to PARPi in a sporadic CRPC patient von Romero-Laorden, N., Piñeiro-Yañez, E., Gutierrez-Pecharroman, A., Pacheco, M.I., Calvo, E., Al-Shahrour, F., Castro, E., Olmos, D.

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GEPAS, an experiment-oriented pipeline for the analysis of microarray gene expression data von Vaquerizas, Juan M., Conde, Lucía, Yankilevich, Patricio, Cabezón, Amaya, Minguez, Pablo, Díaz-Uriarte, Ramón, Al-Shahrour, Fátima, Herrero, Javier, Dopazo, Joaquín

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PupaSNP Finder: a web tool for finding SNPs with putative effect at transcriptional level von Conde, Lucía, Vaquerizas, Juan M., Santoyo, Javier, Al-Shahrour, Fátima, Ruiz-Llorente, Sergio, Robledo, Mercedes, Dopazo, Joaquín

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Testicular cancer and genetic susceptibility: Analysis of Spanish cohort von Autran Gomez, AM, Martin-Gimeno, P., Paumard-Hernández, B., Gonzalez-Enguita, C.C, Garranzo-Ibarrola, M., Oriol, C.O., Inglada-Pérez, L., Tejero, H., Al-Shahrour, F., Pita, G., Barroso, A., Triviño, J.C, Urioste, M., Benitez, J.

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FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes von Al-Shahrour, Fátima, Díaz-Uriarte, Ramón, Dopazo, Joaquín

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New challenges in gene expression data analysis and the extended GEPAS von Herrero, Javier, Vaquerizas, Juan M., Al-Shahrour, Fátima, Conde, Lucía, Mateos, Álvaro, Díaz-Uriarte, Javier Santoyo Ramón, Dopazo, Joaquín

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An in silico analysis identifies drugs potentially modulating the cytokine storm triggered by SARS-CoV-2 infection von Sanchez-Burgos, Laura, Gómez-López, Gonzalo, Al-Shahrour, Fátima, Fernandez-Capetillo, Oscar

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Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells von Sanchez‐Burgos, Laura, Navarro‐González, Belén, García‐Martín, Santiago, Sirozh, Oleksandra, Mota‐Pino, Jorge, Fueyo‐Marcos, Elena, Tejero, Héctor, Antón, Marta Elena, Murga, Matilde, Al‐Shahrour, Fátima, Fernandez‐Capetillo, Oscar

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The 1+Million Genomes Minimal Dataset for Cancer von Riba, Michela, Sala, Cinzia, Culhane, Aedin C., Flobak, Åsmund, Patocs, Attila, Boye, Kjetil, Plevova, Karla, Pospíšilová, Šárka, Gandolfi, Giorgia, Morelli, Marco J., Bucci, Gabriele, Edsjö, Anders, Lassen, Ulrik, Al-Shahrour, Fátima, Lopez-Bigas, Nuria, Hovland, Randi, Cuppen, Edwin, Valencia, Alfonso, Poirel, Helene A., Rosenquist, Richard, Scollen, Serena, Arenas Marquez, Juan, Belien, Jeroen, De Nicolo, Arcangela, De Maria, Ruggero, Torrents, David, Tonon, Giovanni

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1469P The role of the CXCL12/CXCR4 pathway in the immunotherapy of non-small cell lung cancer von Rogado, J., Pozo, F., Troule, K., Pacheco, M., Adrados, M., Sanchez Torres, J.M., Al-Shahrour, F., Alfranca, A., Romero Laorden, N., Colomer Bosch, R.

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BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments von Al-Shahrour, Fátima, Minguez, Pablo, Tárraga, Joaquín, Montaner, David, Alloza, Eva, Vaquerizas, Juan M., Conde, Lucía, Blaschke, Christian, Vera, Javier, Dopazo, Joaquín

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A comprehensive database for integrated analysis of omics data in autoimmune diseases von Martorell-Marugan, Jordi, Lopez-Dominguez, Raul, Garcia-Moreno, Adrian, Toro-Dominguez, Daniel, Villatoro-Garcia, Juan Antonio, Barturen, Guillermo, Martin-Gomez, Adoracion, Troule, Kevin, Gomez-Lopez, Gonzalo, Al-Shahrour, Fatima, Gonzalez-Rumayor, Victor, Pena-Chilet, Maria, Dopazo, Joaquin, Saez-Rodriguez, Julio, Alarcon-Riquelme, Marta E., Carmona-Saez, Pedro

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PD-L1ATTAC mice reveal the potential of depleting PD-L1 expressing cells in cancer therapy von Fueyo-Marcos, Elena, Lopez-Pernas, Gema, Fustero-Torre, Coral, Antón, Marta Elena, Al-Shahrour, Fátima, Fernández-Capetillo, Oscar, Murga, Matilde

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1287P Immune T-cell subpopulations from the peripheral blood of non-small cell lung cancer patients are associated with the efficacy of anti-PD-1 immunotherapy von Rogado, J., Pozo, F., Troulè, K., Sánchez-Torres, J.M., Laorden, N. Romero, Solís, R. Mondéjar, Candil, O. Donnay, García, A.I. Ballesteros, Pacheco-Barcia, V., Aspa, J., Al-Shahrour, F., Alfranca, A., Colomer, R.

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GEPAS: a web-based resource for microarray gene expression data analysis von Herrero, Javier, Al-Shahrour, Fátima, Díaz-Uriarte, Ramón, Mateos, Álvaro, Vaquerizas, Juan M., Santoyo, Javier, Dopazo, Joaquín

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