Postprandial glycogen and lipid synthesis in prednisolone-treated rats maintained on high-protein diets with varied carbohydrate levels von Obeid, Omar A., Boukarim, Leila K., Al Awar, Rima M., Hwalla, Nahla

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Discovery of an MLLT1/3 YEATS Domain Chemical Probe von Moustakim, Moses, Christott, Thomas, Monteiro, Octovia P., Bennett, James, Giroud, Charline, Ward, Jennifer, Rogers, Catherine M., Smith, Paul, Panagakou, Ioanna, Díaz‐Sáez, Laura, Felce, Suet Ling, Gamble, Vicki, Gileadi, Carina, Halidi, Nadia, Heidenreich, David, Chaikuad, Apirat, Knapp, Stefan, Huber, Kilian V. M., Farnie, Gillian, Heer, Jag, Manevski, Nenad, Poda, Gennady, Al‐awar, Rima, Dixon, Darren J., Brennan, Paul E., Fedorov, Oleg

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Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model von Logie, Jennifer, Ganesh, Ahil N, Aman, Ahmed M, Al-awar, Rima S, Shoichet, Molly S

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Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response von Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Barsyte-Lovejoy, Dalia

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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells von Barsyte-Lovejoy, Dalia, Li, Fengling, Oudhoff, Menno J., Tatlock, John H., Dong, Aiping, Zeng, Hong, Wu, Hong, Freeman, Spencer A., Schapira, Matthieu, Senisterra, Guillermo A., Kuznetsova, Ekaterina, Marcellus, Richard, Allali-Hassani, Abdellah, Kennedy, Steven, Lambert, Jean-Philippe, Couzens, Amber L., Aman, Ahmed, Gingras, Anne-Claude, Al-Awar, Rima, Fish, Paul V., Gerstenberger, Brian S., Roberts, Lee, Benn, Caroline L., Grimley, Rachel L., Braam, Mitchell J. S., Rossi, Fabio M. V., Sudol, Marius, Brown, Peter J., Bunnage, Mark E., Owen, Dafydd R., Zaph, Colby, Vedadi, Masoud, Arrowsmith, Cheryl H.

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Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia von Grebien, Florian, Vedadi, Masoud, Getlik, Matthäus, Giambruno, Roberto, Grover, Amit, Avellino, Roberto, Skucha, Anna, Vittori, Sarah, Kuznetsova, Ekaterina, Smil, David, Barsyte-Lovejoy, Dalia, Li, Fengling, Poda, Gennadiy, Schapira, Matthieu, Wu, Hong, Dong, Aiping, Senisterra, Guillermo, Stukalov, Alexey, Huber, Kilian V M, Schönegger, Andreas, Marcellus, Richard, Bilban, Martin, Bock, Christoph, Brown, Peter J, Zuber, Johannes, Bennett, Keiryn L, Al-awar, Rima, Delwel, Ruud, Nerlov, Claus, Arrowsmith, Cheryl H, Superti-Furga, Giulio

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Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2 von Ferreira de Freitas, Renato, Liu, Yanli, Szewczyk, Magdalena M, Mehta, Naimee, Li, Fengling, McLeod, David, Zepeda-Velázquez, Carlos, Dilworth, David, Hanley, Ronan P, Gibson, Elisa, Brown, Peter J, Al-Awar, Rima, James, Lindsey I, Arrowsmith, Cheryl H, Barsyte-Lovejoy, Dalia, Min, Jinrong, Vedadi, Masoud, Schapira, Matthieu, Allali-Hassani, Abdellah

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Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia von Cole, Alicia, Wang, Zezhou, Coyaud, Etienne, Voisin, Veronique, Gronda, Marcela, Jitkova, Yulia, Mattson, Rachel, Hurren, Rose, Babovic, Sonja, Maclean, Neil, Restall, Ian, Wang, Xiaoming, Jeyaraju, Danny V., Sukhai, Mahadeo A., Prabha, Swayam, Bashir, Shaheena, Ramakrishnan, Ashwin, Leung, Elisa, Qia, Yi Hua, Zhang, Nianxian, Combes, Kevin R., Ketela, Troy, Lin, Fengshu, Houry, Walid A., Aman, Ahmed, Al-awar, Rima, Zheng, Wei, Wienholds, Erno, Xu, Chang Jiang, Dick, John, Wang, Jean C.Y., Moffat, Jason, Minden, Mark D., Eaves, Connie J., Bader, Gary D., Hao, Zhenyue, Kornblau, Steven M., Raught, Brian, Schimmer, Aaron D.

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Amphiphilic micelles of poly(2-methyl-2-carboxytrimethylene carbonate- co - d,l -lactide)- graft -poly(ethylene glycol) for anti-cancer drug delivery to solid tumours von Ho, Karyn S, Aman, Ahmed M, Al-awar, Rima S, Shoichet, Molly S

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Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors von Sanches, Mario, Duffy, Nicole M., Talukdar, Manisha, Thevakumaran, Nero, Chiovitti, David, Canny, Marella D., Lee, Kenneth, Kurinov, Igor, Uehling, David, Al-awar, Rima, Poda, Gennadiy, Prakesch, Michael, Wilson, Brian, Tam, Victor, Schweitzer, Colleen, Toro, Andras, Lucas, Julie L., Vuga, Danka, Lehmann, Lynn, Durocher, Daniel, Zeng, Qingping, Patterson, John B., Sicheri, Frank

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Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma von Haftchenary, Sina, Luchman, H. Artee, Jouk, Andriana O, Veloso, Anthony J, Page, Brent D. G, Cheng, Xin Ran, Dawson, Sean S, Grinshtein, Natalie, Shahani, Vijay M, Kerman, Kagan, Kaplan, David R, Griffin, Carly, Aman, Ahmed M, Al-awar, Rima, Weiss, Samuel, Gunning, Patrick T

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Discovery of Nanomolar DCAF1 Small Molecule Ligands von Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud

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Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response von Szewczyk, Magdalena M., Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L., Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, dela Seña, Carlo C., Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Nara, Hiroshi, Barsyte-Lovejoy, Dalia

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WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma von Sun, Yuting, Bell, Jessica L, Carter, Daniel, Gherardi, Samuele, Poulos, Rebecca C, Milazzo, Giorgio, Wong, Jason W H, Al-Awar, Rima, Tee, Andrew E, Liu, Pei Y, Liu, Bing, Atmadibrata, Bernard, Wong, Matthew, Trahair, Toby, Zhao, Quan, Shohet, Jason M, Haupt, Ygal, Schulte, Johannes H, Brown, Peter J, Arrowsmith, Cheryl H, Vedadi, Masoud, MacKenzie, Karen L, Hüttelmaier, Stefan, Perini, Giovanni, Marshall, Glenn M, Braithwaite, Antony, Liu, Tao

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Structure–Activity Relationship of USP5 Inhibitors von Mann, Mandeep K, Zepeda-Velázquez, Carlos A, González-Álvarez, Héctor, Dong, Aiping, Kiyota, Taira, Aman, Ahmed M, Loppnau, Peter, Li, Yanjun, Wilson, Brian, Arrowsmith, Cheryl H, Al-Awar, Rima, Harding, Rachel J, Schapira, Matthieu

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Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport von Zhang, Qiangmin, Xiao, Kunhong, Paredes, José M., Mamonova, Tatyana, Sneddon, W. Bruce, Liu, Hongda, Wang, Dawei, Li, Sheng, McGarvey, Jennifer C., Uehling, David, Al-awar, Rima, Joseph, Babu, Jean-Alphonse, Frederic, Orte, Angel, Friedman, Peter A.

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A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6 von Shen, Yudao, Li, Fengling, Szewczyk, Magdalena M, Halabelian, Levon, Chau, Irene, Eram, Mohammad S, Dela Seña, Carlo, Park, Kwang-Su, Meng, Fanye, Chen, He, Zeng, Hong, McLeod, David, Zepeda-Velázquez, Carlos A, Campbell, Robert M, Mader, Mary M, Watson, Brian M, Schapira, Matthieu, Arrowsmith, Cheryl H, Al-Awar, Rima, Barsyte-Lovejoy, Dalia, Kaniskan, H. Ümit, Brown, Peter J, Vedadi, Masoud, Jin, Jian

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Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma von Ensan, Deeba, Smil, David, Zepeda-Velázquez, Carlos A, Panagopoulos, Dimitrios, Wong, Jong Fu, Williams, Eleanor P, Adamson, Roslin, Bullock, Alex N, Kiyota, Taira, Aman, Ahmed, Roberts, Owen G, Edwards, Aled M, O’Meara, Jeff A, Isaac, Methvin B, Al-awar, Rima

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The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids von Seneviratne, Ayesh K., Xu, Mingjing, Henao, Juan J. Aristizabal, Fajardo, Val A., Hao, Zhenyue, Voisin, Veronique, Xu, G. Wei, Hurren, Rose, Kim, S., MacLean, Neil, Wang, Xiaoming, Gronda, Marcela, Jeyaraju, Danny, Jitkova, Yulia, Ketela, Troy, Mullokandov, Michael, Sharon, David, Thomas, Geethu, Chouinard-Watkins, Raphaël, Hawley, James R., Schafer, Caitlin, Yau, Helen Loo, Khuchua, Zaza, Aman, Ahmed, Al-awar, Rima, Gross, Atan, Claypool, Steven M., Bazinet, Richard P., Lupien, Mathieu, Chan, Steven, De Carvalho, Daniel D., Minden, Mark D., Bader, Gary D., Stark, Ken D., LeBlanc, Paul, Schimmer, Aaron D.

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Correction to "Structure-Activity Relationship of USP5 Inhibitors" von Mann, Mandeep K, Zepeda-Velázquez, Carlos A, González-Álvarez, Héctor, Dong, Aiping, Kiyota, Taira, Aman, Ahmed M, Loppnau, Peter, Li, Yanjun, Wilson, Brian, Arrowsmith, Cheryl H, Al-Awar, Rima, Harding, Rachel J, Schapira, Matthieu

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