Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease von Lunnon, Katie, Smith, Rebecca, Hannon, Eilis, De Jager, Philip L, Srivastava, Gyan, Volta, Manuela, Troakes, Claire, Al-Sarraj, Safa, Burrage, Joe, Macdonald, Ruby, Condliffe, Daniel, Harries, Lorna W, Katsel, Pavel, Haroutunian, Vahram, Kaminsky, Zachary, Joachim, Catharine, Powell, John, Lovestone, Simon, Bennett, David A, Schalkwyk, Leonard C, Mill, Jonathan

Volltext

The genetics and neuropathology of amyotrophic lateral sclerosis von Al-Chalabi, Ammar, Jones, Ashley, Troakes, Claire, King, Andrew, Al-Sarraj, Safa, van den Berg, Leonard H.

Volltext

Multisystem screening reveals SARS‐CoV‐2 in neurons of the myenteric plexus and in megakaryocytes von Gray‐Rodriguez, Sandra, Jensen, Melanie P, Otero‐Jimenez, Maria, Hanley, Brian, Swann, Olivia C, Ward, Patrick A, Salguero, Francisco J, Querido, Nadira, Farkas, Ildiko, Velentza‐Almpani, Elisavet, Weir, Justin, Barclay, Wendy S, Carroll, Miles W, Jaunmuktane, Zane, Brandner, Sebastian, Pohl, Ute, Allinson, Kieren, Thom, Maria, Troakes, Claire, Al‐Sarraj, Safa, Sastre, Magdalena, Gveric, Djordje, Gentleman, Steve, Roufosse, Candice, Osborn, Michael, Alegre‐Abarrategui, Javier

Volltext

Staging of Neurofibrillary Pathology in Alzheimer's Disease: A Study of the BrainNet Europe Consortium von Alafuzoff, Irina, Arzberger, Thomas, Al-Sarraj, Safa, Bodi, Istvan, Bogdanovic, Nenad, Braak, Heiko, Bugiani, Orso, Del-Tredici, Kelly, Ferrer, Isidro, Gelpi, Ellen, Giaccone, Giorgio, Graeber, Manuel B., Ince, Paul, Kamphorst, Wouter, King, Andrew, Korkolopoulou, Penelope, Kovács, Gábor G., Larionov, Sergey, Meyronet, David, Monoranu, Camelia, Parchi, Piero, Patsouris, Efstratios, Roggendorf, Wolfgang, Seilhean, Danielle, Tagliavini, Fabrizio, Stadelmann, Christine, Streichenberger, Nathalie, Thal, Dietmar R., Wharton, Stephen B, Kretzschmar, Hans

Volltext

Frequency and signature of somatic variants in 1461 human brain exomes von Wei, Wei, Keogh, Michael J., Aryaman, Juvid, Golder, Zoe, Kullar, Peter J., Wilson, Ian, Talbot, Kevin, Turner, Martin R., McKenzie, Chris-Anne, Troakes, Claire, Attems, Johannes, Smith, Colin, Sarraj, Safa Al, Morris, Chris M., Ansorge, Olaf, Jones, Nick S., Ironside, James W., Chinnery, Patrick F.

Volltext

Clusterin expression is upregulated following acute head injury and localizes to astrocytes in old head injury von Troakes, Claire, Smyth, Rachel, Noor, Farzana, Maekawa, Satomi, Killick, Richard, King, Andrew, Al‐Sarraj, Safa

Volltext

Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages... von King, Andrew, Sweeney, Fiona, Bodi, Istvan, Troakes, Claire, Maekawa, Satomi, Al-Sarraj, Safa

Volltext

An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associat... von Troakes, Claire, Maekawa, Satomi, Wijesekera, Lokesh, Rogelj, Boris, Siklós, László, Bell, Christopher, Smith, Bradley, Newhouse, Stephen, Vance, Caroline, Johnson, Lauren, Hortobágyi, Tibor, Shatunov, Aleksey, Al-Chalabi, Ammar, Leigh, Nigel, Shaw, Christopher E., King, Andrew, Al-Sarraj, Safa

Volltext

Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive... von King, Andrew, Maekawa, Satomi, Bodi, Istvan, Troakes, Claire, Al-Sarraj, Safa

Volltext

TDP-43 is consistently co-localized with ubiquitinated inclusions in sporadic and Guam amyotrophic lateral sclerosis but not in familial amyotrophic lateral sclerosis with and with... von Maekawa, Satomi, Leigh, P. Nigel, King, Andrew, Jones, Edith, Steele, John C., Bodi, Istvan, Shaw, Christopher E., Hortobagyi, Tibor, Al-Sarraj, Safa

Volltext

Effects of Formalin Fixation, Paraffin Embedding, and Time of Storage on DNA Preservation in Brain Tissue: A BrainNet Europe Study von Ferrer, Isidre, Armstrong, Judith, Capellari, Sabina, Parchi, Piero, Arzberger, Thomas, Bell, Jeanne, Budka, Herbert, Ströbel, Thomas, Giaccone, Giorgio, Rossi, Giacomina, Bogdanovic, Nenad, Fakai, Peter, Schmitt, Andrea, Riederers, Peter, Al-Sarraj, Safa, Ravid, Rivka, Kretzschmar, Hans

Volltext

Distribution patterns of tau pathology in progressive supranuclear palsy von Kovacs, Gabor G., Lukic, Milica Jecmenica, Irwin, David J., Arzberger, Thomas, Respondek, Gesine, Lee, Edward B., Coughlin, David, Giese, Armin, Grossman, Murray, Kurz, Carolin, McMillan, Corey T., Gelpi, Ellen, Compta, Yaroslau, van Swieten, John C., Laat, Laura Donker, Troakes, Claire, Al-Sarraj, Safa, Robinson, John L., Roeber, Sigrun, Xie, Sharon X., Lee, Virginia M.- Y., Trojanowski, John Q., Höglinger, Günter U.

Volltext

Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study von Hanley, Brian, Naresh, Kikkeri N, Roufosse, Candice, Nicholson, Andrew G, Weir, Justin, Cooke, Graham S, Thursz, Mark, Manousou, Pinelopi, Corbett, Richard, Goldin, Robert, Al-Sarraj, Safa, Abdolrasouli, Alireza, Swann, Olivia C, Baillon, Laury, Penn, Rebecca, Barclay, Wendy S, Viola, Patrizia, Osborn, Michael

Volltext

Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia von McAleese, Kirsty E., Colloby, Sean J., Thomas, Alan J., Al‐Sarraj, Safa, Ansorge, Olaf, Neal, James, Roncaroli, Federico, Love, Seth, Francis, Paul T., Attems, Johannes

Volltext

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology von Smith, Rebecca G., Hannon, Eilis, De Jager, Philip L., Chibnik, Lori, Lott, Simon J., Condliffe, Daniel, Smith, Adam R., Haroutunian, Vahram, Troakes, Claire, Al-Sarraj, Safa, Bennett, David A., Powell, John, Lovestone, Simon, Schalkwyk, Leonard, Mill, Jonathan, Lunnon, Katie

Volltext

A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex von Marzi, Sarah J., Leung, Szi Kay, Ribarska, Teodora, Hannon, Eilis, Smith, Adam R., Pishva, Ehsan, Poschmann, Jeremie, Moore, Karen, Troakes, Claire, Al-Sarraj, Safa, Beck, Stephan, Newman, Stuart, Lunnon, Katie, Schalkwyk, Leonard C., Mill, Jonathan

Volltext

p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS von Al-Sarraj, Safa, King, Andrew, Troakes, Claire, Smith, Bradley, Maekawa, Satomi, Bodi, Istvan, Rogelj, Boris, Al-Chalabi, Ammar, Hortobágyi, Tibor, Shaw, Christopher E.

Volltext

The phenotypic spectrum of progressive supranuclear palsy: A retrospective multicenter study of 100 definite cases von Respondek, Gesine, Stamelou, Maria, Kurz, Carolin, Ferguson, Leslie W., Rajput, Alexander, Chiu, Wan Zheng, van Swieten, John C., Troakes, Claire, al Sarraj, Safa, Gelpi, Ellen, Gaig, Carles, Tolosa, Eduardo, Oertel, Wolfgang H., Giese, Armin, Roeber, Sigrun, Arzberger, Thomas, Wagenpfeil, Stefan, Höglinger, Günter U.

Volltext

A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases von Smith, Adam R., Smith, Rebecca G., Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Kalaria, Rajesh N., Sloan, Carolyn, Robinson, Andrew C., Mill, Jonathan, Lunnon, Katie

Volltext

Variation in 5-hydroxymethylcytosine across human cortex and cerebellum von Lunnon, Katie, Hannon, Eilis, Smith, Rebecca G, Dempster, Emma, Wong, Chloe, Burrage, Joe, Troakes, Claire, Al-Sarraj, Safa, Kepa, Agnieszka, Schalkwyk, Leonard, Mill, Jonathan

Volltext