Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage von Ali, Shabana Amanda, Al‐Jazrawe, Mushriq, Ma, Henry, Whetstone, Heather, Poon, Raymond, Farr, Sarah, Naples, Mark, Adeli, Khosrow, Alman, Benjamin A.

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A Metabolomics Pilot Study on Desmoid Tumors and Novel Drug Candidates von Mercier, Kelly A., Al-Jazrawe, Mushriq, Poon, Raymond, Acuff, Zachery, Alman, Benjamin

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Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis von Rockel, Jason S, Yu, Chunying, Whetstone, Heather, Craft, April M, Reilly, Katherine, Ma, Henry, Tsushima, Hidetoshi, Puviindran, Vijitha, Al-Jazrawe, Mushriq, Keller, Gordon M, Alman, Benjamin A

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Targeting Stem Cell Behavior in Desmoid Tumors (Aggressive Fibromatosis) by Inhibiting Hedgehog Signaling von Ghanbari-Azarnier, Ronak, Sato, Shingo, Wei, Qingxia, Al-Jazrawe, Mushriq, Alman, Benjamin A

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CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping von Naert, Thomas, Tulkens, Dieter, Van Nieuwenhuysen, Tom, Przybyl, Joanna, Demuynck, Suzan, van de Rijn, Matt, Al-Jazrawe, Mushriq, Alman, Benjamin A., Coucke, Paul J., De Leeneer, Kim, Vanhove, Christian, Savvides, Savvas N., Creytens, David, Vleminckx, Kris

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Abstract 5897: Single cell-derived analysis of desmoid tumors for studying tumor-stroma interactions von Al-Jazrawe, Mushriq, Xu, Steven, Wei, Qingxia, Poon, Raymond, Alman, Benjamin

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Abstract PO-093: Evaluating dependencies by rapid image-based ex vivo cancer biosensors von Al-Jazrawe, Mushriq, Molnar, Csaba, Rindtorff, Niklas, Eser, Pinar, Misek, Sean, Alimova, Maria, Ursu, Oana, Colgan, William, Attari, Adel, Tsang, Natalie, Keskula, Paula, Rios, Carmen, Tseng, Moony, Carpenter, Anne, McFarland, James, Bass, Adam, Klempner, Samuel, Boehm, Jesse

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Abstract 4349: Regulation of proliferation and platelet-derived growth factor expression in desmoid tumors by microRNA-29 von Al-Jazrawe, Mushriq, Poon, Raymond, Liu, Jessica, Alman, Benjamin

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CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation von Al-Jazrawe, Mushriq, Xu, Steven, Poon, Raymond, Wei, Qingxia, Przybyl, Joanna, Varma, Sushama, van de Rijn, Matt, Alman, Benjamin A

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Abstract 697: Partnering with patients to create a rare soft tissue sarcoma target discovery platform as a community resource von Cebula, Kathryn, Johnson, Grace, Al-Jazrawe, Mushriq, Lernman, Irene, Van Hare, Barbara, Rios, Carmen, Tseng, Moony, Boehm, Jesse

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Hedgehog inhibits [Beta]-catenin activity in synovial joint development and osteoarthritis von Rockel, Jason S, Yu, Chunying, Whetstone, Heather, Craft, April M, Reilly, Katherine, Ma, Henry, Tsushima, Hidetoshi, Puviindran, Vijitha, Al-Jazrawe, Mushriq, Keller, Gordon M, Alman, Benjamin A

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Abstract 5324: Drug repurposing and genetic screening strategies for effective treatment discovery in soft-tissue sarcomas von Al-Jazrawe, Mushriq, Cebula, Kathryn, Abeyta, Elisabeth A., Curtis, Haley S., McIninch, Jane K., Cheah, Jaime H., Berstler, James, Miller, Lisa, Neiswender, James, Brenan, Lisa, Burger, Mike, Vazquez, Francisca, Boehm, Jesse S.

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Abstract 1117: Rapid label-free imaging-based evaluation of cancer dependencies in zero-passage primary cells von Al-Jazrawe, Mushriq, Molnar, Csaba, Abeyta, Elisabeth, Blum, Steven, Rindtorff, Niklas, Cebula, Kathryn, Misek, Sean, Alimova, Maria, Colgan, William, Rios, Carmen, Tseng, Moony, McFarland, James, Regev, Aviv, Cimini, Beth, Carpenter, Anne, Bass, Adam, Klempner, Samuel, Boehm, Jesse

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Abstract 639: Rapidly evaluating cancer dependencies by label-free imaging of zero-passage primary cells von Al-Jazrawe, Mushriq, Molnar, Csaba, Rindtorff, Niklas, Blum, Steven, Colgan, William, Alimova, Maria, Misek, Sean, Rios, Carmen, Tseng, Moony, McFarland, James M., Regev, Aviv, Cimini, Beth A., Carpenter, Anne E., Bass, Adam, Klempner, Samuel J., Boehm, Jesse

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Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma von Zhang, Hongyuan, Wei, Qingxia, Tsushima, Hidetoshi, Puviindran, Vijitha, Tang, Yuning J, Pathmanapan, Sinthu, Poon, Raymond, Ramu, Eyal, Al-Jazrawe, Mushriq, Wunder, Jay, Alman, Benjamin A

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Targeting Stem Cell Behavior in Desmoid Tumors (Aggressive Fibromatosis) by Inhibiting Hedgehog Signaling1 von Ghanbari-Azarnier, Ronak, Sato, Shingo, Wei, Qingxia, Al-Jazrawe, Mushriq, Alman, Benjamin A

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In desmoid-type fibromatosis cells sorafenib induces ferroptosis and apoptosis, which are enhanced by autophagy inhibition von Schut, Anne-Rose W., Vriends, Anne L.M., Sacchetti, Andrea, Timbergen, Milea J.M., Alman, Benjamin A., Al-Jazrawe, Mushriq, Grünhagen, Dirk J., Verhoef, Cornelis, Sleijfer, Stefan, Wiemer, Erik A.C.

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Abstract 319: Cholesterol inhibition reduces Hh mediated chondrosarcoma von Wei, Qingxia, Ramu, Eyal, AL-Jazrawe, Mushriq, Poon, Raymond, Wunder, Jay, Alman, Benjamin

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LIVING BIOSENSORS von Tsherniak, Aviad, Al-Jazrawe, Mushriq Muhib, Boehm, Jesse, Rindtorff, Niklas, Neal, JT

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