HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms von Yue, Lanzhu, Sharma, Vasundhara, Horvat, Nathan P., Akuffo, Afua A., Beatty, Matthew S., Murdun, Cem, Colin, Christelle, Billington, Julia M.R., Goodheart, William E., Sahakian, Eva, Zhang, Ling, Powers, John J., Amin, Narmin E., Lambert-Showers, Que T., Darville, Lancia N., Pinilla-Ibarz, Javier, Reuther, Gary W., Wright, Kenneth L., Conti, Chiara, Lee, Jennifer Y., Zheng, Xiaozhang, Ng, Pui Yee, Martin, Matthew W., Marshall, C. Gary, Koomen, John M., Levine, Ross L., Verma, Amit, Grimes, H. Leighton, Sotomayor, Eduardo M., Shao, Zonghong, Epling-Burnette, Pearlie K.

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Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation von Park, Derek S, Akuffo, Afua A, Muench, David E, Grimes, H Leighton, Epling-Burnette, Pearlie K, Maini, Philip K, Anderson, Alexander R A, Bonsall, Michael B

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Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon von Akuffo, Afua A., Alontaga, Aileen Y., Metcalf, Rainer, Beatty, Matthew S., Becker, Andreas, McDaniel, Jessica M., Hesterberg, Rebecca S., Goodheart, William E., Gunawan, Steven, Ayaz, Muhammad, Yang, Yan, Karim, Md Rezaul, Orobello, Morgan E., Daniel, Kenyon, Guida, Wayne, Yoder, Jeffrey A., Rajadhyaksha, Anjali M., Schönbrunn, Ernst, Lawrence, Harshani R., Lawrence, Nicholas J., Epling-Burnette, Pearlie K.

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Circulating Immunosuppressive Regulatory T Cells Predict Risk of Incident Cutaneous Squamous Cell Carcinoma von Rollison, Dana E, Messina, Jane L, Cherpelis, Basil S, Fenske, Neil A, Schell, Michael J, Adeegbe, Dennis O, Zhao, Yayi, Amorrortu, Rossybelle P, Akuffo, Afua A, Hesterberg, Rebecca S, Epling-Burnette, Pearlie K

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Growth, metastasis, and expression of CCL2 and CCL5 by murine mammary carcinomas are dependent upon Myd88 von Egunsola, Adetutu T., Zawislak, Carolyn L., Akuffo, Afua A., Chalmers, Samantha A., Ewer, Jason C., Vail, Caroline M., Lombardo, Jeffrey C., Perez, Dana N., Kurt, Robert A.

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SHP2 inhibition displays efficacy as a monotherapy and in combination with JAK2 inhibition in preclinical models of myeloproliferative neoplasms von Pandey, Garima, Mazzacurati, Lucia, Rowsell, Tegan M., Horvat, Nathan P., Amin, Narmin E., Zhang, Guolin, Akuffo, Afua A., Colin‐Leitzinger, Christelle M., Haura, Eric B., Kuykendall, Andrew T., Zhang, Ling, Epling‐Burnette, Pearlie K., Reuther, Gary W.

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T Regulatory Cell Subpopulations Associated with Recent Ultraviolet Radiation Exposure in a Skin Cancer Screening Cohort von Hesterberg, Rebecca S, Amorrortu, Rossybelle P, Zhao, Yayi, Hampras, Shalaka, Akuffo, Afua A, Fenske, Neil, Cherpelis, Basil, Balliu, Juliana, Vijayan, Laxmi, Epling-Burnette, Pearlie K, Rollison, Dana E

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Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes von Hesterberg, Rebecca S., Beatty, Matthew S., Han, Ying, Fernandez, Mario R., Akuffo, Afua A., Goodheart, William E., Yang, Chunying, Chang, Shiun, Colin, Christelle M., Alontaga, Aileen Y., McDaniel, Jessica M., Mailloux, Adam W., Billington, Julia M.R., Yue, Lanzhu, Russell, Shonagh, Gillies, Robert J., Yun, Sang Y., Ayaz, Muhammad, Lawrence, Nicholas J., Lawrence, Harshani R., Yu, Xue-Zhong, Fu, Jianing, Darville, Lancia N., Koomen, John M., Ren, Xiubao, Messina, Jane, Jiang, Kun, Garrett, Timothy J., Rajadhyaksha, Anjali M., Cleveland, John L., Epling-Burnette, Pearlie K.

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Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma von DOUGHERTY, Joseph D, FOMCHENKO, Elena I, AKUFFO, Afua A, SCHMIDT, Eric, HELMY, Karim Y, BAZZOLI, Elena, BRENNAN, Cameron W, HOLLAND, Eric C, MILOSEVIC, Ana

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SHP2 Inhibition Suppresses RAS-ERK Signaling, the Development of JAK2 Inhibitor Persistence, and MPN Development in Pre-Clinical Models of Myeloproliferative Neoplasms von Pandey, Garima, Horvat, Nathan, Amin, Narmin E., Zhang, Guolin, Mazzacurati, Lucia, Akuffo, Afua A., Colin-Leitzinger, Christelle, Haura, Eric B., Epling-Burnette, Pearlie K., Reuther, Gary W.

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RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms von Pandey, Garima, Horvat, Nathan, Amin, Narmin E., Akuffo, Afua A., Colin, Christelle, Epling-Burnette, Pearlie K., Reuther, Gary W.

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Abstract 4960: Recent ultraviolet radiation exposure and circulating immunosuppressive T-regulatory cells von Rollison, Dana E., Hampras, Shalaka S., Messina, Jane L., Fenske, Neil A., Cherpelis, Basil S., Schell, Michael J., Reed, Rhianna, Balliu, Juliana, Hesterberg, Rebecca, Akuffo, Afua A., Burnette, Pearlie K.

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Controversy regarding the functional conservation of cereblon CUL4-type E3 ligase substrate receptor von A Akuffo, Afua, Y Alontaga, Aileen, R Lawrence, Harshani, J. Lawrence, Nicholas, K Epling-Burnette, Pearlie

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Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation von Park, Derek S, Akuffo, Afua A, Muench, David E, Grimes, H. Leighton, Epling-Burnette, Pearlie K, Maini, Philip K, Anderson, Alexander R. A, Bonsall, Michael B

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Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation von Dalal, Jasbir, Roh, Jee Hoon, Maloney, Susan E, Akuffo, Afua, Shah, Samir, Yuan, Han, Wamsley, Brie, Jones, Wendell B, de Guzman Strong, Cristina, Gray, Paul A, Holtzman, David M, Heintz, Nathaniel, Dougherty, Joseph D

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SHP2 Inhibition Enhances JAK2 Inhibitor Therapy in Preclinical Models of Myeloproliferative Neoplasms von Pandey, Garima, Mazzacurati, Lucia, Horvat, Nathan P., Rowsell, Tegan, Amin, Narmin E., Zhang, Guolin, Akuffo, Afua Adutwumwa, Colin-Leitzinger, Christelle M., Haura, Eric B., Kuykendall, Andrew T., Epling-Burnette, PK, Reuther, Gary W.

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Cereblon tunes c-Myc protein expression and regulates the metabolic function of activated T cells von Epling-Burnette, Pearlie, Hesterberg, Rebecca, Akuffo, Afua Adutwumwa, Beatty, Matthew S., Goodheart, William E., Fernandez, Mario, Cleveland, John L.

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Implementation of a Delayed Prescribing Model to Reduce Antibiotic Prescribing for Suspected Upper Respiratory Tract Infections in a Hospital Outpatient Department, Ghana von Ghebrehewet, Sam, Shepherd, Wendi, Panford-Quainoo, Edwin, Shantikumar, Saran, Decraene, Valerie, Rajendran, Rajesh, Kaushal, Menaal, Akuffo, Afua, Ayerh, Dinah, Amofah, George

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Selective Targeting of Histone Deacetylase 11 Disables Metabolism of Myeloproliferative Neoplasms von Sharma, Vasundhara, Yue, Lanzhu, Horvat, Nathan P., Christodoulidou, Agni, Akuffo, Afua Adutwumwa, Beatty, Mathew, Murdun, Cem, Billington, Julia, Goodheart, William E, Sahakian, Eva, Zhang, Ling, Powers, John J., Amin, Narmin E., Lambert-Showers, Que T., Darville, Lancia, Pinilla Ibarz, Javier, Reuther, Gary W., Lee, Jennifer, Zheng, Xiaozhang, Yee Ng, Pui, Martin, Mathew W., Marshall, Gary C., Koomen, John M., Levine, Ross L., Verma, Amit, Grimes, H. Leighton, Sotomayor, Eduardo, Shao, Zonghong, Wright, Kenneth, Epling-Burnette, Pearlie K.

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Skin homing and highly suppressive (CD45RA−CD27−) Tregs associated with ultraviolet radiation exposure von Hesterberg, Rebecca, Akuffo, Afua Adutwumwa, Hampras, Shalaka S, Messina, Jane L, Fenske, Neil A, Cherpelis, Basil, Schell, Michael J, Reed, Rhianna, Balliu, Juliana, Rollison, Dana E, Epling-Burnette, Pearlie K

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