Low copy numbers of complement C4 and C4A deficiency are risk factors for myositis, its subgroups and autoantibodies von Zhou, D, King, EH, Rothwell, S, Krystufkova, O, Notarnicola, A, Coss, S, Abdul-Aziz, R, Miller, KE, Dang, A, Yu, GR, Drew, J, Lundstrom, E, Pachman, LM, Mamyrova, G, Curiel, R, De Paepe, B, De Bleecker, JL, Payton, A, Ollier, W, O'Hanlon, TP, Targoff, IN, Flegel, WA, Sivaraman, V, Oberle, E, Akoghlanian, S, Driest, K, Spencer, CH, Wu, YL, Nagaraja, HN, Ardoin, SP, Chinoy, H, Rider, LG, Miller, FW, Lundberg, IE, Padyukov, L, Vencovsky, J, Lamb, JA, Yu, CY

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Complement C4 gene copy number variations and polymorphisms, autoantibodies, and clinical manifestations of juvenile dermatomyositis– a multi-center study von Coss, Samantha Lynn, Aziz, Rabheh Abdul, Zhou, Danlei, Zhou, Bi, Miller, Katherine, Wu, Yee Ling, Ardoin, Stacy, Oberle, Edward, Driest, Kyla, Al Ahmed, Ohoud, Patwardhan, Anjali, Akoghlanian, Shoghik, Sivaraman, Vidya, Barbar-Smiley, Fatima, Drew, Joanne, Spencer, Charles, Pachman, Lauren, Morgan, Gabrielle, Mamyrova, Gulnara, Curiel, Rodolfo, Jones, Olcay, O’Hanlon, Terry, Rider, Lisa, Miller, Frederick, Padyukov, Leonid, Lundberg, Ingrid, Notarnicola, Antonella, Vencovský, Jiří, Stibůrková, Blanka, Kryštůfková, Olga, Yu, Chack-Yung

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International Consensus for the Dosing of Corticosteroids in Childhood‐Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis von Chalhoub, Nathalie E., Levy, Deborah M., Rouster‐Stevens, Kelly, Aggarwal, Amita, Qiu, Tingting, Merritt, Angela, Onel, Karen, Khubchandani, Raju P., Ciurtin, Coziana, Kasapcopur, Ozgur, Jelusic, Marija, Ozen, Seza, Klein‐Gitelman, Marisa S., Lim, Sern Chin, Silva, Clovis A., Torres‐Jimenez, Alfonso‐Ragnar, Trachana, Maria, Devarajan, Prasad, Brunner, Hermine I., Abulaban, Khalid, Aguiar, Cassyanne, Ahn, Sun‐Young, Akoghlanian, Shoghik, Aljaberi, Najla, Angeles‐Han, Sheila, Balboni, Imelda, Barbar‐Smiley, Fatima, Beary, John, Brakeman, Paul, Bridges, John, Burgos‐Vargas, Ruben, Cabral, David A., Cameto, Juan, Chédeville, Gaëlle, Chhakchhuak, Christine, Chiraseveenuprapund, Peter, Cifuentes Alvarado, Mayra, De Quattro, Kimberly, Dizon, Brian, Duong, Minh Dien, Eberhard, Anne, Ede, Kaleo, Espada, Graciela, Fritz, Deborah, Gilbert, Mileka, Gittar, Patsy, Greenbaum, Larry, Grom, Alexei, Gulati, Gaurav, Hersh, Aimee, Hiskey, Megan, Hoffmann, Sarah, Hollander, Matthew, Houk, Lawrence, Houk, J. Brian, Hsieh, Elena W.Y., Hsu, Joyce, Jensen, Paul, Jurado, Rosario, Kallash, Mahmoud, Kamphuis, Sylvia, Khanna, Surabhi, Kim, Susan, Kimseng, Karen Joy, Kunder, Rebecca, Lai, Jamie, Laskin, Benjamin, Linda, Wagner‐Weiner, Lo, Mindy, Lovell, Daniel, Luggen, Michael, Mansuri, Asif, Mason, Sherene, Mohammed, Abdul, Moncrieffe, Halima, Moorthy, Lakshmi, Mosquera, Angela, Myones, Barry, Nocton, James, Olson, Judyann, Orrock, Janet, Paim‐Marques, Luciana, Pain, Clare, Park, Catherine, Pereira, Maria, Rheault, Michelle, Ronis, Tova, Sadun, Rebecca, Siddiqi, Nabeela, Smitherman, Emily, Srinivasalu, Hemalatha, Syed, Reema, Ting, Tracy, Toth, Mary, Turnier, Jessica, Vashisht, Priyanka, von Scheven, Emily, Ware, Avis, Wu, Eveline, Lawson, Erica

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Improved Disease Course Associated With Early Initiation of Biologics in Polyarticular Juvenile Idiopathic Arthritis: Trajectory Analysis of a Childhood Arthritis and Rheumatology... von Ringold, Sarah, Kimura, Yukiko, Aiello, J., Alperin, R., Anderson, E., Armendariz, S., Baker, E., Balmuri, N., Becker, M., Bigley, T., Black, C., Brooks, E., Brown, A., Buckley, M., Buckley, M., Cameron, B., Chalom, E., Chang, J., Chang‐Hoftman, A., Connor, R., Cooper, J., Curry, M., Davis, A., De Ranieri, D., Dvergsten, J., Federici, S., Ferrucho, R., Fleming, C., Fox, E., Franco, L., Gilbert, M., Godiwala, C., Gottlieb, B., Guevara, M., Harel, L., Hartigan, E., Hayward, K., Hekl, K., Henrickson, M., Hill, P., Hiskey, M., Hung, C., Insalaco, A., Jackson, S., Jones, K., Kienzle, B., Kracker, J., Lapidus, S., Laxer, R., Lerman, M., Levy, D., Li, S., Ling, N., McCurdy, D., McMullen‐Jackson, C., Milojevic, D., Morgan, S., Mruk, V., Nadler, R., Nasah, N., Neely, J., Newhall, L., Osei‐Onomah, S., Pardeo, M., Rivas‐Chacon, R., Rojas, K., Ronis, T., Rosolowski, B., Rouster‐Stevens, K., Saad, N., Sabbagh, S., Shalen, J., Shenoi, S., Silverman, E., Singer, N., Son, M., Stevenson, R., Stewart, K., Stokes, J., Stoll, M., Stringer, E., Sutter, M., Tambralli, A., Thatayatikom, A., Tipp, A., Torok, K., Tory, H., Van Mater, H., Vasquez, N., Vazzana, K., Veiga, K., Velez, J., Waite, H., Weiss, J., White, A., Wright, T., Yalcindag, A., Yen, E., Zartoshti, A., Zhao, Y.

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Racial Disparities and Achievement of the Low Lupus Disease Activity State (LLDAS): A CARRA Registry Study von Soulsby, William Daniel, Olveda, Rebecca, He, Jie, Berbert, Laura, Weller, Edie, Barbour, Kamil E, Greenlund, Kurt J, Schanberg, Laura E, von Scheven, Emily, Hersh, Aimee, Son, Mary Beth F, Chang, Joyce, Knight, Andrea

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Childhood‐Onset Lupus Nephritis in the Childhood Arthritis and Rheumatology Research Alliance Registry: Short‐Term Kidney Status and Variation in Care von Rahman, A. K. M. Fazlur, Aiello, J., Ambler, W., Armendariz, S., Balmuri, N., Barillas‐Arias, L., Benham, H., Black, C., Brothers, M., Brown, A., Brunner, H., Bukulmez, H., Cameron, B., Carper, P., Cerracchio, L., Chira, P., Chundru, K., Clairman, H., Co, D., Cooper, A., Correll, C., Curiel‐Duran, L., Dalrymple, A., Davis, A., Davis, C., Davis, C., Dedeoglu, F., Dorsey, E., Duverger, E., Eberhard, A., Edens, C., Fadrhonc, S., Favier, L., Federici, S., Ferreira, B., Fleming, C., Gerhold, K., Gillispie‐Taylor, M., Godiwala, C., Goldsmith, D., Gracia, C., Grevich, S., Griswold, J., Guevara, M., Guittar, P., Hance, M., Hausmann, J., Hayward, K., Hobday, P., Holland, M., Hsu, J., Hui‐Yuen, J., Ibarra, M., Jared, S., Kim, S., Kingsbury, D., Kremer, C., Lam, J., Lawson, E., Lim, L., Lovell, D., Madison, C., Malla, B., McCormick, E., McGuire, S., Modica, R., Moore, K., Muscal, E., Newhall, L., Nicholas, J., O'Brien, B., O'Brien, T., Osei‐Onomah, S., Parsons, A., Pfeiffer, T., Puplava, B., Riskalla, M., Ronis, T., Roth‐Wojcicki, E., Santiago, L., Savani, S., Schmitt, E., Schollaert‐Fitch, K., Schulert, G., Seper, C., Singer, N., Smith, C., Spence, S., Stingl, C., Syverson, G., Tambralli, A., Thomas, B., Torok, K., Toruner, C., Van Mater, H., Williams, C., Wise, A., Yomogida, K., Zeft, A., Zic, C.

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Comparative Effectiveness of a Second Tumor Necrosis Factor Inhibitor Versus a Non–Tumor Necrosis Factor Biologic in the Treatment of Patients With Polyarticular‐Course Juvenile Id... von Kearsley‐Fleet, Lianne, Hyrich, Kimme L., Aamir, R., Ambler, W., Balboni, I., Basiaga, M., Baszis, K., Behrens, E., Blakley, M., Buckley, L., Bullock, D., Castro, D., Dalrymple, A., Datyner, E., Dean, J., Dunnock, K., El Tal, T., Elder, M., Ferguson, P., Ferguson, I., Flanagan, E., Franklin, L., Fuller, J., Gerstbacher, D., Gilbert, M., Gorry, S., Gottlieb, B., Griffin, T., Grom, A., Hammond, T., Harris, J., Hay, A., Henderson, L., Holland, M., Hui‐Yuen, J., Ibarra, M., Kafisheh, D., Kasinathan, S., Kimura, Y., Kitcharoensakkul, M., Kremer, C., Lasky, A., Lawson, E., Limenis, E., Mason, T., McBrearty, K., McCurdy, D., McDonald, J., Meidan, E., Moreno, J., Murphy, A., Nasah, N., Nassi, L., Nativ, S., Nguyen, A., Nolan, B., Olveda, R., Orandi, A., Paller, A., Patel, J., Patrizi, S., Perron, M., Peskin, M., Quinlan‐Waters, M., Robinson, L., Rodriquez, M., Rogers, D., Ronis, T., Rothermel, H., Rouster‐Stevens, K., Sabbagh, S., Sadun, R., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Sherman, M., Smith, C., Smith, J., Spitznagle, J., Sterba Rakovchik, Y., Sullivan, J., Szymanski, A., Tanner, T., Tarvin, S., Taylor, J., Thakurdeen, T., Twachtman‐Bassett, J., Valdovinos, R., Varghese, C., Vora, S., Wahezi, D., Waters, A., Williams, C., Wright, T., Wu, E., Yalcindag, A., Yeung, R., Zhang, Y., Zhu, A.

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Disease Recapture Rates After Medication Discontinuation and Flare in Juvenile Idiopathic Arthritis: An Observational Study Within the Childhood Arthritis and Rheumatology Research... von Ringold, Sarah, Beukelman, Timothy, Shrader, Peter, Phillips, Thomas A., Schanberg, Laura E., Ardoin, S., Basiaga, M., Baszis, K., Boneparth, A., Bowman, S., Bullock, D., Carper, P., Cerracchio, L., Cooper, A., DeGuzman, M., Dorsey, E., Drew, J., Durkee, D., Ede, K., Edens, C., Edens, C., Failing, C., Falcon, M., Flynn, O., Fuhlbrigge, R., Giverc, E., Goh, I., Gracia, C., Graham, T., Hammelev, E., Harris, J., Hay, A., Henderson, L., Hobday, P., Hollander, M., Hsu, J., Huttenlocher, A., Imundo, L., Inman, C., Jared, S., Justice, C., Kessler, E., Kimura, Y., Kingsbury, D., Lam, J., Lasky, A., Lawson, E., Lentini, L., Lin, C., Lingis, M., Lovell, D., Lvovich, S., Malloy, M., Marques, L., Martyniuk, A., McConnell, K., McCormick, E., Meidan, E., Merritt, A., Mitchell, M., Modica, R., Dewitt, E. Morgan, Moussa, T., Natter, M., Ng, L., Oberle, E., O'Brien, T., Oliver, M., Orlando, M., Paller, A., Paredes, J., Pfeiffer, T., Marafon, D. Pires, Prahalad, S., Radhakrishna, S., Reid, H., Ritter, M., Roth‐Wojcicki, E., Ruth, N., Smith, J., Smith, J., Smitherman, E., Soep, J., Spitznagle, J., Steigerwald, K., Sumner, J., Syverson, G., Tal, R., Tesher, M., Thomas, B., Uriguen, S., Verbsky, J., Volpe, N., Vora, S., Walker, J., Watts, A., Weiser, P., Wise, A., Yee, M., Zeft, A.

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Race, ethnicity and patient-reported outcomes in childhood-onset systemic lupus erythematosus von Borgia, R Ezequiel, Gurka, Matthew J, Filipp, Stephanie L, Elder, Melissa, Cardel, Michelle, Shiff, Natalie J

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Health Equity Implications of Missing Data Among Youths With Childhood-Onset Systemic Lupus Erythematosus: A Proof-of-Concept Study in the Childhood Arthritis and Rheumatology Rese... von Woo, Jennifer M P, Simmonds, Faith, Dennos, Anne, Son, Mary Beth F, Lewandowski, Laura B, Rubinstein, Tamar B

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Trajectories of disease activity in patients with JIA in the Childhood Arthritis and Rheumatology Research Alliance Registry von Shiff, Natalie J, Shrader, Peter, Correll, Colleen K, Dennos, Anne, Phillips, Thomas, Beukelman, Timothy

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Down Syndrome–Associated Arthritis Cohort in the New Childhood Arthritis and Rheumatology Research Alliance Registry: Clinical Characteristics, Treatment, and Outcomes von Becker, Mara L., Adams, M., Agbayani, R., Amarilyo, G., Bernal, W., Boland, J., Brooks, E., Cartwright, V., Chalom, E., Chang, J., Chang‐Hoftman, A., Connor, R., Dean, J., DeGuzman, M., Delnay, N., Donaldson, B., Dover, S., Dowling, J., Duarte, K., Edgerly, Y., Fields, K., George, N., Goh, I., Gotte, A., Griffin, T., Hammelev, E., Hay, A., Henderson, L., Hickey, K., Hiraki, L., Hsu, J., Janow, G., Johnson, N., Joshi, S., Justice, C., Khalsa, U., Kitcharoensakkul, M., Klein, K., Klein‐Gitelman, M., Kosikowski, A., Lasky, A., Lentini, L., Lin, C., Lingis, M., Lvovich, S., Maller, J., Malloy, M., Mannion, M., Manos, C., Marques, L., Martyniuk, A., McAllister, L., Merritt, A., Miller, M., Mitchell, M., Morgan Dewitt, E., Mulvhihill, E., Natter, M., Nelson, B., Ng, L., Nguyen, E., Oberle, E., Parsons, A., Pratt, S., Raisian, J., Ramsay, E., Richmond, A., Rodriquez, M., Rosolowski, B., Saad, N., Sabbagh, S., Sadun, R., Schanberg, L., Scharnhorst, S., Schmeling, H., Schneider, R., Sheets, R., Shenoi, S., Silverman, E., Sivaraman, V., Sterba Rakovchik, Y., Stewart, K., Stingl, C., Stoll, M., Strelow, J., Sumner, J., Tarshish, G., Tesher, M., Thomas, B., Tipp, A., Toruner, C., Van Mater, H., Vazzana, K., von Scheven, E., Vora, S., Wang, C., Weiser, P., Wise, A., Yee, M., Zhu, A.

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The new Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry: design, rationale, and characteristics of patients enrolled in the first 12 months von Beukelman, Timothy, Kimura, Yukiko, Ilowite, Norman T, Mieszkalski, Kelly, Natter, Marc D, Burrell, Grendel, Best, Brian, Jones, Jason, Schanberg, Laura E

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Increase in pediatric recurrent fever evaluations during the first year of the COVID-19 pandemic in North America von Mansfield, Leanne M, Lapidus, Sivia K, Romero, Samira Nazzar, Moorthy, Lakshmi N, Adler-Shohet, Felice C, Hollander, Matthew, Cherian, Julie, Twilt, Marinka, Lionetti, Geraldina, Mohan, Smriti, DeLaMora, Patricia A, Durrant, Karen L, Muskardin, Theresa Wampler, Correia Marques, Mariana, Onel, Karen B, Dedeoglu, Fatma, Gutierrez, Maria J, Schulert, Grant

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Placeholder TextIntraarticular steroids as DMARD-sparing agents for juvenile idiopathic arthritis flares: Analysis of the Childhood Arthritis and Rheumatology Research Alliance Reg... von Hahn, Timothy, Daymont, Carrie, Beukelman, Timothy, Groh, Brandt, Hays, Kimberly, Bingham, Catherine April, Scalzi, Lisabeth

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Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses von Saper, Vivian E., Kuo, Christin S., Bader-Meunier, Brigitte, Espada, Graciela, Flanagan, Elaine R., Imundo, Lisa F., Lake, Carol, Ogunjimi, Benson, Poholek, Catherine, Ravelli, Angelo, Shilo, Natalie R., Sura, Angeli, Vasquez-Canizares, Natalia, Sharma, Surbhi, Akinsete, A., Akoghlanian, S., Al Manaa, M., Ardoin, S., Ballinger, S., Baluta, S., Basiaga, M., Baszis, K., Castro, D., Connor, R., Cooper, A., Corbin, K., Dean, J., Dizon, B., Drew, J., Edens, C., Fadrhonc, S., Failing, C., Favier, L., Figueroa, C., Futch-West, T., Gagne, S., Gennaro, V., Graham, T., Hahn, T., Harel, L., Hausmann, J., Hays, K., Hayward, K., Henrickson, M., Hoffart, C., Hong, S., Huber, A., Klein-Gitelman, M., Kovalick, L., Kramer, S., Kudas, O., Lang, B., Lapidus, S., Lapin, B., Lawler, C., Lee, P., Lerman, M., Levinsky, Y., Li, S., Lin, C., Livny, R., Lopez-Peña, M., Luca, N., Manos, C., McColl, J., Nearanz, K., Oberle, E., Toledano, A. Pappo, Parsons, A., Quinlan-Waters, M., Rabinovich, C., Randell, R., Reed, A., Reiff, D., Riordan, M., Robinson, A., Rosado, A., Rothschild, E., Rubinstein, T., Schmitt, E., Seper, C., Spiegel, L., Stevens, B., Stewart, W., Sundel, R., Swaffar, C., Swayne, N., Syed, R., Tate, L., Theisen, A., Torok, K., Tory, H., Tsin, C., Valcarcel, T., Van Mater, H., Vandenbergen, S., Verstegen, R., Walters, H., Weiss, P., Zeft, A.

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First-line options for systemic juvenile idiopathic arthritis treatment: an observational study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans von Beukelman, Timothy, Tomlinson, George, Nigrovic, Peter A, Dennos, Anne, Del Gaizo, Vincent, Jelinek, Marian, Riordan, Mary Ellen, Schanberg, Laura E, Mohan, Shalini, Pfeifer, Erin, Kimura, Yukiko

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Low Gene Copy Numbers (GCN) of complement C4 and C4A deficiency are highly significant genetic risk factors for idiopathic inflammatory myopathies and its major subgroups von Zhou, D, King, E, Rothwell, S, Krystufkova, O, Notarnicola, A, Coss, S, Aziz, R, Miller, K, Dang, A, Yu, R, Drew, J, Lundstrom, E, Pachman, L, Mamyrova, G, Curiel, R, De Paepe, B, De Bleecker, J, Payton, A, Ollier, W, O'Hanlon, T, Targoff, I, Flegel, W, Sivaraman, V, Obele, E, Akoghlanian, S, Driest, K, Spencer, C, Wu, YL, Nagaraja, H, Ardoin, S, Chinoy, H, Rider, L, Miller, F, Lundberg, I, Padyukov, L, Vencovsky, J, Lamb, J, Yu, CY

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LOW GENE COPY NUMBERS OF COMPLEMENT C4 AND COMPLEMENT C4A DEFICIENCY ARE STRONG AND HIGHLY SIGNIFICANT GENETIC RISK FACTORS FOR IDIOPATHIC INFLAMMATORY MYOPATHY AND ITS MAJOR SUBGR... von Zhou, DL, King, EH, Rothwell, S, Krystufkova, O, Notarnicola, A, Aziz, RA, Lundstrom, E, Blanka, S, Pachman, LM, Mamyrova, G, de Paepe, B, de Bleecker, J, O'Hanlon, TP, Coss, S, Miller, KL, Dang, A, Yu, GR, Drew, J, Sivaraman, V, Oberle, E, Akoghlanian, S, Driest, K, Spencer, CH, Wu, YL, Ardoin, SP, Rider, LG, Chinoy, H, Miller, FW, Lundberg, IE, Padyukov, L, Vencovsky, J, Lamb, JA, Yu, CY

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Delivering clinical trials at home: protocol, design and implementation of a direct-to-family paediatric lupus trial von Randell, Rachel L, Singler, Lindsay, Cunningham, Anthony, Schanberg, Laura E, Cohen-Wolkowiez, Michael, Hornik, Christoph P, Balevic, Stephen J

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