Targeting Hedgehog--a cancer stem cell pathway von Merchant, Akil A, Matsui, William

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GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML von Chaudhry, Parvesh, Singh, Mohan, Triche, Timothy J., Guzman, Monica, Merchant, Akil A.

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The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels von Merchant, Akil A., Singh, Anju, Matsui, William, Biswal, Shyam

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Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses von Contreras-Trujillo, Humberto, Eerdeng, Jiya, Akre, Samir, Jiang, Du, Contreras, Jorge, Gala, Basia, Vergel-Rodriguez, Mary C., Lee, Yeachan, Jorapur, Aparna, Andreasian, Areen, Harton, Lisa, Bramlett, Charles S., Nogalska, Anna, Xiao, Gang, Lee, Jae-Woong, Chan, Lai N., Müschen, Markus, Merchant, Akil A., Lu, Rong

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Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926 von Lin, Tara L, Wang, Qiuju H, Brown, Patrick, Peacock, Craig, Merchant, Akil A, Brennan, Sarah, Jones, Evan, McGovern, Karen, Watkins, D Neil, Sakamoto, Kathleen M, Matsui, William

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Molecular signatures of proliferation and quiescence in hematopoietic stem cells von Venezia, Teresa A, Merchant, Akil A, Ramos, Carlos A, Whitehouse, Nathan L, Young, Andrew S, Shaw, Chad A, Goodell, Margaret A

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Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry von Gerdtsson, Erik, Pore, Milind, Thiele, Jana-Aletta, Gerdtsson, Anna Sandström, Malihi, Paymaneh D, Nevarez, Rafael, Kolatkar, Anand, Velasco, Carmen Ruiz, Wix, Sophia, Singh, Mohan, Carlsson, Anders, Zurita, Amado J, Logothetis, Christopher, Merchant, Akil A, Hicks, James, Kuhn, Peter

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Primary Cilia are Present on Human Blood and Bone Marrow Cells and Mediate Hedgehog Signaling von Singh, Mohan, Chaudhry, Parvesh, Merchant, Akil A

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Low booster uptake in cancer patients despite health benefits von Figueiredo, Jane C., Levy, Julia, Choi, So Yung, Xu, Alexander M., Merin, Noah M., Hamid, Omid, Lemos, Tucker, Nguyen, Nathalie, Nadri, Maimoona, Gonzalez, Alma, Mahov, Simeon, Darrah, Justin M., Gong, Jun, Paquette, Ronald L., Mita, Alain C., Vescio, Robert A., Salvy, Sarah J., Mehmi, Inderjit, Hendifar, Andrew E., Natale, Ronald, Tourtellotte, Warren G., Ramanujan, V. Krishnan, Huynh, Carissa A., Sobhani, Kimia, Reckamp, Karen L., Merchant, Akil A.

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Efficacy of inotuzumab ozogamicin in patients with Philadelphia chromosome–positive relapsed/refractory acute lymphoblastic leukemia von Stock, Wendy, Martinelli, Giovanni, Stelljes, Matthias, DeAngelo, Daniel J., Gökbuget, Nicola, Advani, Anjali S., O’Brien, Susan, Liedtke, Michaela, Merchant, Akil A., Cassaday, Ryan D., Wang, Tao, Zhang, Hui, Vandendries, Erik, Jabbour, Elias, Marks, David I., Kantarjian, Hagop M.

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EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT von Merchant, Akil A., Jorapur, Aparna, McManus, Amy, Liu, Ren, Krasnoperov, Valery, Chaudhry, Parvesh, Singh, Mohan, Harton, Lisa, Agajanian, Mary, Kim, Miriam, Triche, Timothy J., Druker, Brian J., Tyner, Jeffrey W., Gill, Parkash S.

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Not so benign haematology: anaemia of the elderly von Merchant, Akil A., Roy, Cindy N.

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Chloroquine Improves Survival and Hematopoietic Recovery After Lethal Low-Dose-Rate Radiation von Lim, Yiting, B.S, Hedayati, Mohammad, Ph.D, Merchant, Akil A., M.D, Zhang, Yonggang, M.D, Yu, Hsiang-Hsuan M., M.D, Kastan, Michael B., M.D., Ph.D, Matsui, William, M.D, DeWeese, Theodore L., M.D

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Hepatic adverse event profile of inotuzumab ozogamicin in adult patients with relapsed or refractory acute lymphoblastic leukaemia: results from the open-label, randomised, phase 3... von Kantarjian, Hagop M, DeAngelo, Daniel J, Advani, Anjali S, Stelljes, Matthias, Kebriaei, Partow, Cassaday, Ryan D, Merchant, Akil A, Fujishima, Naohito, Uchida, Toshiki, Calbacho, Maria, Ejduk, Anna A, O'Brien, Susan M, Jabbour, Elias J, Zhang, Hui, Sleight, Barbara J, Vandendries, Erik R, Marks, David I

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Public Concern About Monitoring Twitter Users and Their Conversations to Recruit for Clinical Trials: Survey Study von Reuter, Katja, Zhu, Yifan, Angyan, Praveen, Le, NamQuyen, Merchant, Akil A, Zimmer, Michael

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Evidence for diversity in transcriptional profiles of single hematopoietic stem cells von Ramos, Carlos A, Bowman, Teresa A, Boles, Nathan C, Merchant, Akil A, Zheng, Yayun, Parra, Irma, Fuqua, Suzanne A W, Shaw, Chad A, Goodell, Margaret A

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Hematopoietic fingerprints: an expression database of stem cells and their progeny von Chambers, Stuart M, Boles, Nathan C, Lin, Kuan-Yin K, Tierney, Megan P, Bowman, Teresa V, Bradfute, Steven B, Chen, Alice J, Merchant, Akil A, Sirin, Olga, Weksberg, David C, Merchant, Mehveen G, Fisk, C Joseph, Shaw, Chad A, Goodell, Margaret A

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Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections von Somisetty, Medha, Mack, Philip C., Hsu, Chih-Yuan, Huang, Yuanhui, Gomez, Jorge E., Rodilla, Ananda M., Cagan, Jazz, Tavolacci, Sooyun C., Carreño, Juan Manuel, Brody, Rachel, Moore, Amy C., King, Jennifer C., Rohs, Nicholas C., Rolfo, Christian, Bunn, Paul A., Minna, John D., Bhalla, Sheena, Krammer, Florian, García-Sastre, Adolfo, Figueiredo, Jane C., Kazemian, Elham, Reckamp, Karen L., Merchant, Akil A., Nadri, Maimoona, Ahmed, Rafi, Ramalingam, Suresh S., Shyr, Yu, Hirsch, Fred R., Gerber, David E.

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Mantle cell lymphoma activation enhances bortezomib sensitivity von Brennan, Sarah K., Meade, Brooke, Wang, Qiuju, Merchant, Akil A., Kowalski, Jeanne, Matsui, William

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Smoothening the Controversial Role of Hedgehog in Hematopoiesis von Merchant, Akil A., Matsui, William

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