High throughput screening aids clinical decision‐making in refractory acute myeloid leukaemia von Jessop, S. J., Fuentos‐Bolanos, N., Mayoh, C., Dolman, M. E. M., Tax, G., Wong‐Erasmus, M., Ajuyah, P., Tyrell, V., Marshall, G. M., Ziegler, D. S., Lau, L. M. S.

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438 (PB426): Precision-guided treatment improves outcomes for children with highrisk cancers von Lau, L., Khoung-Quang, D.A., Chelsea, M., Wong, M., Barahona, P., Ajuyah, P., Senapati, A., Nagabushan, S., Sherstyuk, A., Altekoester, A.K., Fuentes-Bolanos, N., Sullivan, A., Mateos, M., Tyrrell, N., Haber, M., Trahair, T., Cowley, M., Marshall, G., Ekert, P., Ziegler, D.

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Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes von Ajuyah, P, Ajuyah, P, Mayoh, C, https://orcid.org/0000-0002-6398-3046, Mayoh, C, Lau, LMS, Lau, LMS, https://orcid.org/0000-0002-3172-0970, Barahona, P, Barahona, P, Wong, M, Wong, M, Chambers, H, Chambers, H, Valdes-Mora, F, Valdes-Mora, F, Senapati, A, Senapati, A, Gifford, AJ, Gifford, AJ, https://orcid.org/0000-0002-4092-2347, D’Arcy, C, Hansford, JR, Hansford, JR, Manoharan, N, https://orcid.org/0000-0002-2914-8637, Manoharan, N, Nicholls, W, Nicholls, W, Williams, MM, Williams, MM, Wood, PJ, Wood, PJ, Cowley, MJ, https://orcid.org/0000-0002-9519-5714, Cowley, MJ, Tyrrell, V, Tyrrell, V, Haber, M, Haber, M, https://orcid.org/0000-0003-2036-8817, Ekert, PG, https://orcid.org/0000-0002-2976-8617, Ekert, PG, Ziegler, DS, Ziegler, DS, https://orcid.org/0000-0001-7451-7916, Khuong-Quang, DA, Khuong-Quang, DA, Valdes Mora, Fatima, https://orcid.org/0000-0001-7490-0114, Valdes Mora, Fatima

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A novel orthotopic patient-derived xenograft model of radiation-induced glioma following medulloblastoma von Whitehouse, JP, Howlett, M, Hii, H, Mayoh, C, Wong, M, Barahona, P, Ajuyah, P, White, CL, Buntine, MK, Dyke, JM, Lee, S, Valvi, S, Stanley, J, Andradas, C, Carline, B, Kuchibhotla, M, Ekert, PG, Cowley, MJ, Gottardo, NG, Endersby, R, Wong-Erasmus, Marie

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In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma von Whitehouse, Jacqueline P, Hii, Hilary, Mayoh, Chelsea, Wong, Marie, Ajuyah, Pamela, Barahona, Paulette, Cui, Louise, Dholaria, Hetal, White, Christine L, Buntine, Molly K, Byrne, Jacob, Rodrigues da Silva, Keteryne, Howlett, Meegan, Girard, Emily J, Tsoli, Maria, Ziegler, David S, Dyke, Jason M, Lee, Sharon, Ekert, Paul G, Cowley, Mark J, Gottardo, Nicholas G, Endersby, Raelene

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A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma von Whitehouse, Jacqueline P., Howlett, Meegan, Hii, Hilary, Mayoh, Chelsea, Wong, Marie, Barahona, Paulette, Ajuyah, Pamela, White, Christine L., Buntine, Molly K., Dyke, Jason M., Lee, Sharon, Valvi, Santosh, Stanley, Jason, Andradas, Clara, Carline, Brooke, Kuchibhotla, Mani, Ekert, Paul G., Cowley, Mark J., Gottardo, Nicholas G., Endersby, Raelene

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