Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay von Hall, Justin, Brault, Amy, Vincent, Fabien, Weng, Shawn, Wang, Hong, Dumlao, Darren, Aulabaugh, Ann, Aivazian, Dikran, Castro, Dana, Chen, Ming, Culp, Jeffrey, Dower, Ken, Gardner, Joseph, Hawrylik, Steven, Golenbock, Douglas, Hepworth, David, Horn, Mark, Jones, Lyn, Jones, Peter, Latz, Eicke, Li, Jing, Lin, Lih-Ling, Lin, Wen, Lin, David, Lovering, Frank, Niljanskul, Nootaree, Nistler, Ryan, Pierce, Betsy, Plotnikova, Olga, Schmitt, Daniel, Shanker, Suman, Smith, James, Snyder, William, Subashi, Timothy, Trujillo, John, Tyminski, Edyta, Wang, Guoxing, Wong, Jimson, Lefker, Bruce, Dakin, Leslie, Leach, Karen

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Therapeutic Effects of FGF23 c‐tail Fc in a Murine Preclinical Model of X‐Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption von Johnson, Kristen, Levine, Kymberly, Sergi, Joseph, Chamoun, Jean, Roach, Rachel, Vekich, Jacqueline, Favis, Mike, Horn, Mark, Cao, Xianjun, Miller, Brian, Snyder, William, Aivazian, Dikran, Reagan, William, Berryman, Edwin, Colangelo, Jennifer, Markiewicz, Victoria, Bagi, Cedo M, Brown, Thomas P, Coyle, Anthony, Mohammadi, Moosa, Magram, Jeanne

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Lipid-Binding Activity of Intrinsically Unstructured Cytoplasmic Domains of Multichain Immune Recognition Receptor Signaling Subunits von Sigalov, Alexander B, Aivazian, Dikran A, Uversky, Vladimir N, Stern, Lawrence J

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TIP47 is a key effector for Rab9 localization von Aivazian, Dikran, Serrano, Ramon L, Pfeffer, Suzanne

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Conserved amino acid networks involved in antibody variable domain interactions von Wang, Norman, Smith, William F., Miller, Brian R., Aivazian, Dikran, Lugovskoy, Alexey A., Reff, Mitchell E., Glaser, Scott M., Croner, Lisa J., Demarest, Stephen J.

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A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity von Dong, Jianying, Sereno, Arlene, Aivazian, Dikran, Langley, Emma, Miller, Brian R., Snyder, William B, Chan, Eric, Cantele, Matt, Morena, Ronald, Joseph, Ingrid B.J.K., Boccia, Antonio, Virata, Cyrus, Gamez, James, Yco, Grace, Favis, Michael, Wu, Xiufeng, Graff, Christilyn P., Wang, Qin, Rohde, Ellen, Rennard, Rachel, Berquist, Lisa, Huang, Flora, Zhang, Ying, Gao, Sharon X., Ho, Steffan N., Demarest, Stephen J., Reff, Mitchell E., Hariharan, Kandasamy, Glaser, Scott M.

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Targeting Rab GTPases to distinct membrane compartments von Pfeffer, Suzanne, Aivazian, Dikran

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Purification and Properties of Yip3/PRA1 as a Rab GDI Displacement Factor von Sivars, Ulf, Aivazian, Dikran, Pfeffer, Suzanne

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Homooligomerization of the Cytoplasmic Domain of the T Cell Receptor ζ Chain and of Other Proteins Containing the Immunoreceptor Tyrosine-Based Activation Motif von Sigalov, Alexander, Aivazian, Dikran, Stern, Lawrence

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Yip3 catalyses the dissociation of endosomal Rab-GDI complexes von Pfeffer, Suzanne R, Sivars, Ulf, Aivazian, Dikran

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A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator von Šedý, John R., Balmert, M. Olivia, Ware, Brian C., Smith, Wendell, Nemčovičova, Ivana, Norris, Paula S., Miller, Brian R., Aivazian, Dikran, Ware, Carl F.

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A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator von Sedy, John, Balmert, Mary Olivia, Re, Audrey, Moshayedi, Aref, Ware, Brian, Smith, Wendell, Nemcovicova, Ivana, Norris, Paula S., Miller, Brian R., Aivazian, Dikran, Ware, Carl

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Cancer Mutations Targeting TNFRSF14 alter Microenvironment Checkpoint Interactions to Limit Tumor Clearance by Cytotoxic Cells von Sedy, John R, Balmert, Mary Olivia, Nguyen, Jennifer, Ware, Brian C, Bjordahl, Ryan, Norris, Paula S, Miller, Brian R, Aivazian, Dikran, Ware, Carl F

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Therapeutic Effects of FGF23 c-tail Fc in a murine pre-clinical model of X-linked hypophosphatemia via the selective modulation of phosphate reabsorption von Johnson, Kristen, Levine, Kymberly, Sergi, Joseph, Chamoun, Jean, Roach, Rachel, Vekich, Jackie, Favis, Mike, Horn, Mark, Cao, Xianjun, Miller, Brian, Snyder, William, Aivazian, Dikran, Reagan, William, Berryman, Edwin, Colangelo, Jennifer, Markiewicz, Victoria, Bagi, Cedo, Brown, Thomas P., Coyle, Anthony, Mohammadi, Moosa, Magram, Jeanne

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Structure Induction of the T-Cell Receptor ζ-Chain upon Lipid Binding Investigated by NMR Spectroscopy von Duchardt, Elke, Sigalov, Alexander B., Aivazian, Dikran, Stern, Lawrence J., Schwalbe, Harald

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T1P47 is a key effector for Rab9 localization von Aivazian, Dikran, Serrano, Ramon L, Pfeffer, Suzanne

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Phosphorylation of T cell receptor ζ is regulated by a lipid dependent folding transition von Stern, Lawrence J, Aivazian, Dikran

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Receptor clustering and transmembrane signaling in T cells von Cochran, Jennifer R, Aivazian, Dikran, Cameron, Thomas O, Stern, Lawrence J

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Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I) von Zhang, Lin, Fan, Junhua, Chong, Jer-Hong, Cesena, Angela, Tam, Betty Y.Y., Gilson, Charles, Boykin, Christina, Wang, Deping, Aivazian, Dikran, Marcotte, Doug, Xiao, Guangqing, Le Brazidec, Jean-Yves, Piao, Jinhua, Lundgren, Karen, Hong, Kevin, Vu, Khang, Nguyen, Khanh, Gan, Liang-Shang, Silvian, Laura, Ling, Leona, Teng, Min, Reff, Mitchell, Takeda, Nicole, Timple, Noel, Wang, Qin, Morena, Ron, Khan, Samina, Zhao, Shuo, Li, Tony, Lee, Wen-Cherng, Taveras, Arthur G., Chao, Jianhua

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Phosphorylation of T cell receptor [zeta] is regulated by a lipid dependent folding transition von Aivazian, Dikran, Stern, Lawrence J

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