A novel KLF6-Rho GTPase axis regulates hepatocellular carcinoma cell migration and dissemination von Ahronian, L G, Zhu, L J, Chen, Y-W, Chu, H-C, Klimstra, D S, Lewis, B C

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664P Final results of a phase I/II study of combined BCL-xL and MEK inhibition with navitoclax and trametinib in KRAS or NRAS mutant advanced solid tumors von Corcoran, R.B., Do, K.T., Cleary, J., Parikh, A., Yeku, O., Weekes, C.D., Ahronian, L., Mauri, G., Tian, J., Brugge, J., Juric, D., Flaherty, K.T., Sullivan, R.J., Clark, J., Heist, R., Matulonis, U.A., Liu, J.F., Shapiro, G.I.

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447PDPhase I/II study of combined BCL-XL and MEK inhibition with navitoclax (N) and trametinib (T) in KRAS or NRAS mutant advanced solid tumours von Corcoran, R B, Do, K T, Cleary, J M, Parikh, A R, Yeku, O O, Weekes, C D, Veneris, J, Ahronian, L G, Mauri, G, Seventer, E E Van, Fetter, I J, Gurski, J M, Matulonis, U A, Juric, D, Flaherty, K T, Sullivan, R J, Clark, J W, Heist, R S, Shapiro, G I

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Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer von Russo, Mariangela, Siravegna, Giulia, Blaszkowsky, Lawrence S, Corti, Giorgio, Crisafulli, Giovanni, Ahronian, Leanne G, Mussolin, Benedetta, Kwak, Eunice L, Buscarino, Michela, Lazzari, Luca, Valtorta, Emanuele, Truini, Mauro, Jessop, Nicholas A, Robinson, Hayley E, Hong, Theodore S, Mino-Kenudson, Mari, Di Nicolantonio, Federica, Thabet, Ashraf, Sartore-Bianchi, Andrea, Siena, Salvatore, Iafrate, A John, Bardelli, Alberto, Corcoran, Ryan B

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Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations von Ahronian, Leanne G, Sennott, Erin M, Van Allen, Eliezer M, Wagle, Nikhil, Kwak, Eunice L, Faris, Jason E, Godfrey, Jason T, Nishimura, Koki, Lynch, Kerry D, Mermel, Craig H, Lockerman, Elizabeth L, Kalsy, Anuj, Gurski, Jr, Joseph M, Bahl, Samira, Anderka, Kristin, Green, Lisa M, Lennon, Niall J, Huynh, Tiffany G, Mino-Kenudson, Mari, Getz, Gad, Dias-Santagata, Dora, Iafrate, A John, Engelman, Jeffrey A, Garraway, Levi A, Corcoran, Ryan B

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Molecular Heterogeneity and Receptor Coamplification Drive Resistance to Targeted Therapy in MET-Amplified Esophagogastric Cancer von Kwak, Eunice L, Ahronian, Leanne G, Siravegna, Giulia, Mussolin, Benedetta, Borger, Darrell R, Godfrey, Jason T, Jessop, Nicholas A, Clark, Jeffrey W, Blaszkowsky, Lawrence S, Ryan, David P, Lennerz, Jochen K, Iafrate, A John, Bardelli, Alberto, Hong, Theodore S, Corcoran, Ryan B

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Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G Celine, Liu, David, Ahronian, Leanne G, Shahzade, Heather A, Chen, Lifeng, Parikh, Aparna R, Allen, Jill N, Clark, Jeffrey W, Kwak, Eunice L, Faris, Jason E, Murphy, Janet E, Hong, Theodore S, Van Seventer, Emily E, Nadres, Brandon, Hong, Catriona B, Gurski, Joseph M, Jessop, Nicholas A, Dias-Santagata, Dora, Iafrate, A John, Van Allen, Eliezer M, Corcoran, Ryan B

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Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAF V600E Colorectal Cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G Celine, Liu, David, Ahronian, Leanne G, Shahzade, Heather A, Chen, Lifeng, Parikh, Aparna R, Allen, Jill N, Clark, Jeffrey W, Kwak, Eunice L, Faris, Jason E, Murphy, Janet E, Hong, Theodore S, Van Seventer, Emily E, Nadres, Brandon, Hong, Catriona B, Gurski, Jr, Joseph M, Jessop, Nicholas A, Dias-Santagata, Dora, Iafrate, A John, Van Allen, Eliezer M, Corcoran, Ryan B

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Abstract LB-A34: Modeling convergent therapeutic strategies to overcome the heterogeneity of acquired resistance in BRAF -mutant colorectal cancer von Hazar-Rethinam, Mehlika, Kleyman, Marianna, Han, G. Celine, Liu, David, Ahronian, Leanne G., Shahzade, Heather A., Chen, Lifeng, Parikh, Aparna R., Allen, Jill N., Clark, Jeffrey W., Kwak, Eunice L., Faris, Jason E., Murphy, Janet E., Hong, Theodore S., Seventer, Emily E. Van, Nadres, Brandon, Hong, Catriona B., Gurski, Joseph M., Jessop, Nicholas A., Dias-Santagata, Dora, Iafrate, A. John, Van Allen, Eli M., Corcoran, Ryan B.

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Abstract NG04: Clinical acquired resistance to RAF inhibitor combinations in BRAF mutant colorectal cancer through MAPK pathway alterations von Corcoran, Ryan B., Ahronian, Leanne G., Van Allen, Eliezer, Coffee, Erin M., Wagle, Nikhil, Kwak, Eunice L., Faris, Jason E., Iafrate, A. John, Garraway, Levi A., Engelman, Jeffrey A.

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Abstract 878: Tumor heterogeneity and lesion-specific response to targeted therapy in colorectal cancer von Russo, Mariangela, Siravegna, Giulia, Blaszkowsky, Lawrence S., Corti, Giorgio, Crisafulli, Giovanni, Ahronian, Leanne G., Mussolin, Benedetta, Kwak, Eunice L., Buscarino, Michela, Lazzari, Luca, Valtorta, Emanuele, Truini, Mauro, Jessop, Nicholas A., Robinson, Hayley E., Hong, Theodore S., Mino-Kenudson, Mari, Di Nicolantonio, Federica, Thabet, Ashraf, Sartore-Bianchi, Andrea, Siena, Salvatore, Iafrate, A John, Corcoran, Ryan B., Bardelli, Alberto

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Abstract PR01: Acquisition of resistance to anti-EGFR therapy drives genomic heterogeneity and lesion-specific responses in colorectal cancer von Siravegna, Giulia, Russo, Mariangela, Blaszkowsky, Lawrence S., Corti, Giorgio, Crisafulli, Giovanni, Ahronian, Leanne G., Mussolin, Benedetta, Kwak, Eunice L., Buscarino, Michela, Lazzari, Luca, Valtorta, Emanuele, Truini, Mauro, Jessop, Nicholas A., Robinson, Hayley E., Hong, Theodore S., Mino-Kenudson, Mari, Di Nicolantonio, Federica, Thabet, Ashraf, Sartore-Bianchi, Andrea, Siena, Salvatore, Iafrate, John, Corcoran, Ryan B., Bardelli, Alberto

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Abstract LB-055: Clinical acquired resistance to RAF inhibitor combinations in BRAF-mutant colorectal cancer through MAPK pathway alterations von Ahronian, Leanne G., Sennott, Erin M., Van Allen, Eliezer M., Wagle, Nikhil, Kwak, Eunice L., Faris, Jason E., Godfrey, Jason T., Nishimura, Koki, Lynch, Kerry D., Mermel, Craig H., Lockerman, Elizabeth L., Kalsy, Anuj, Gurski, Joseph M., Bahl, Samira, Anderka, Kristin, Green, Lisa M., Lennon, Niall J., Huynh, Tiffany G., Mino-Kenudson, Mari, Getz, Gad, Dias-Santagata, Dora, Iafrate, A. John, Engelman, Jeffrey A., Garraway, Levi A., Corcoran, Ryan B.

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Molecular heterogeneity and receptor co-amplification drive resistance to targeted therapy in MET-amplified esophagogastric cancer von Kwak, Eunice L., Ahronian, Leanne G., Siravegna, Giulia, Mussolin, Benedetta, Godfrey, Jason T., Clark, Jeffrey W., Blaszkowsky, Lawrence S., Ryan, David P., Lennerz, Jochen K., Iafrate, A. John, Bardelli, Alberto, Hong, Theodore S., Corcoran, Ryan B.

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Les noms composés anglais et français du domaine d’Internet : une radiographie bilingue von Ahronian, Céline, Béjoint, Henri

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