Mutation of herpesvirus thymidine kinase to generate ganciclovir-specific kinases for use in cancer gene therapies von Mercer, Kelly E., Ahn, Christina E., Coke, Amanda, Compadre, Cesar M., Drake, Richard R.

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Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors von Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.

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ZZ-dependent regulation of p62/SQSTM1 in autophagy von Zhang, Yi, Mun, Su Ran, Linares, Juan F., Ahn, JaeWoo, Towers, Christina G., Ji, Chang Hoon, Fitzwalter, Brent E., Holden, Michael R., Mi, Wenyi, Shi, Xiaobing, Moscat, Jorge, Thorburn, Andrew, Diaz-Meco, Maria T., Kwon, Yong Tae, Kutateladze, Tatiana G.

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Physical Activity in Older Adults: an Ecological Approach von Thornton, Christina M., Kerr, Jacqueline, Conway, Terry L., Saelens, Brian E., Sallis, James F., Ahn, David K., Frank, Lawrence D., Cain, Kelli L., King, Abby C.

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Clinical Outcomes in Patients with Multi-Hit TP53 Chronic Lymphocytic Leukemia Treated with Ibrutinib von Brieghel, Christian, Aarup, Kathrine, Torp, Mathias H, Andersen, Michael A, Yde, Christina W, Tian, Xin, Wiestner, Adrian, Ahn, Inhye E, Niemann, Carsten U

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The repertoire of mutational signatures in human cancer von Alexandrov, Ludmil B., Kim, Jaegil, Haradhvala, Nicholas J., Huang, Mi Ni, Tian Ng, Alvin Wei, Wu, Yang, Boot, Arnoud, Covington, Kyle R., Gordenin, Dmitry A., Bergstrom, Erik N., Islam, S. M. Ashiqul, Lopez-Bigas, Nuria, Klimczak, Leszek J., McPherson, John R., Morganella, Sandro, Sabarinathan, Radhakrishnan, Wheeler, David A., Mustonen, Ville, Getz, Gad, Rozen, Steven G., Stratton, Michael R.

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The evolutionary history of 2,658 cancers von Gerstung, Moritz, Jolly, Clemency, Leshchiner, Ignaty, Dentro, Stefan C., Gonzalez, Santiago, Rosebrock, Daniel, Mitchell, Thomas J., Rubanova, Yulia, Anur, Pavana, Yu, Kaixian, Tarabichi, Maxime, Deshwar, Amit, Wintersinger, Jeff, Kleinheinz, Kortine, Vázquez-García, Ignacio, Haase, Kerstin, Jerman, Lara, Sengupta, Subhajit, Macintyre, Geoff, Malikic, Salem, Donmez, Nilgun, Livitz, Dimitri G., Cmero, Marek, Demeulemeester, Jonas, Schumacher, Steven, Fan, Yu, Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Boutros, Paul C., Bowtell, David D., Zhu, Hongtu, Getz, Gad, Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

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Patterns of somatic structural variation in human cancer genomes von Li, Yilong, Roberts, Nicola D., Wala, Jeremiah A., Shapira, Ofer, Schumacher, Steven E., Kumar, Kiran, Khurana, Ekta, Waszak, Sebastian, Korbel, Jan O., Haber, James E., Imielinski, Marcin, Weischenfeldt, Joachim, Beroukhim, Rameen, Campbell, Peter J.

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Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing von Cortés-Ciriano, Isidro, Lee, Jake June-Koo, Xi, Ruibin, Jain, Dhawal, Jung, Youngsook L., Yang, Lixing, Gordenin, Dmitry, Klimczak, Leszek J., Zhang, Cheng-Zhong, Pellman, David S., Park, Peter J.

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A paracrine requirement for hedgehog signalling in cancer von Yauch, Robert L., Gould, Stephen E., Scales, Suzie J., Tang, Tracy, Tian, Hua, Ahn, Christina P., Marshall, Derek, Fu, Ling, Januario, Thomas, Kallop, Dara, Nannini-Pepe, Michelle, Kotkow, Karen, Marsters, James C., Rubin, Lee L., de Sauvage, Frederic J.

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Genomic basis for RNA alterations in cancer von Calabrese, Claudia, Davidson, Natalie R., Demircioğlu, Deniz, Fonseca, Nuno A., He, Yao, Kahles, André, Lehmann, Kjong-Van, Liu, Fenglin, Shiraishi, Yuichi, Soulette, Cameron M., Urban, Lara, Greger, Liliana, Li, Siliang, Liu, Dongbing, Perry, Marc D., Xiang, Qian, Zhang, Fan, Zhang, Junjun, Bailey, Peter, Erkek, Serap, Hoadley, Katherine A., Hou, Yong, Huska, Matthew R., Kilpinen, Helena, Korbel, Jan O., Marin, Maximillian G., Markowski, Julia, Nandi, Tannistha, Pan-Hammarström, Qiang, Pedamallu, Chandra Sekhar, Siebert, Reiner, Stark, Stefan G., Su, Hong, Tan, Patrick, Waszak, Sebastian M., Yung, Christina, Zhu, Shida, Awadalla, Philip, Creighton, Chad J., Meyerson, Matthew, Ouellette, B. F. Francis, Wu, Kui, Yang, Huanming, Brazma, Alvis, Brooks, Angela N., Göke, Jonathan, Rätsch, Gunnar, Schwarz, Roland F., Stegle, Oliver, Zhang, Zemin

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Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition von Rodriguez-Martin, Bernardo, Alvarez, Eva G., Baez-Ortega, Adrian, Zamora, Jorge, Supek, Fran, Demeulemeester, Jonas, Santamarina, Martin, Ju, Young Seok, Temes, Javier, Garcia-Souto, Daniel, Detering, Harald, Li, Yilong, Rodriguez-Castro, Jorge, Dueso-Barroso, Ana, Bruzos, Alicia L., Dentro, Stefan C., Blanco, Miguel G., Contino, Gianmarco, Ardeljan, Daniel, Tojo, Marta, Roberts, Nicola D., Zumalave, Sonia, Edwards, Paul A., Weischenfeldt, Joachim, Puiggròs, Montserrat, Chong, Zechen, Chen, Ken, Lee, Eunjung Alice, Wala, Jeremiah A., Raine, Keiran M., Butler, Adam, Waszak, Sebastian M., Navarro, Fabio C. P., Schumacher, Steven E., Monlong, Jean, Maura, Francesco, Bolli, Niccolo, Bourque, Guillaume, Gerstein, Mark, Park, Peter J., Wedge, David C., Beroukhim, Rameen, Torrents, David, Korbel, Jan O., Martincorena, Iñigo, Fitzgerald, Rebecca C., Van Loo, Peter, Kazazian, Haig H., Burns, Kathleen H., Campbell, Peter J., Tubio, Jose M. C.

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Comprehensive molecular characterization of mitochondrial genomes in human cancers von Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han

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The landscape of viral associations in human cancers von Zapatka, Marc, Borozan, Ivan, Brewer, Daniel S., Iskar, Murat, Grundhoff, Adam, Alawi, Malik, Desai, Nikita, Sültmann, Holger, Moch, Holger, Cooper, Colin S., Eils, Roland, Ferretti, Vincent, Lichter, Peter

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Smoothened Mutation Confers Resistance to a Hedgehog Pathway Inhibitor in Medulloblastoma von Yauch, Robert L., Dijkgraaf, Gerrit J. P., Alicke, Bruno, Januario, Thomas, Ahn, Christina P., Holcomb, Thomas, Pujara, Kanan, Stinson, Jeremy, Callahan, Christopher A., Tang, Tracy, Bazan, J. Fernando, Kan, Zhengyan, Seshagiri, Somasekar, Hann, Christine L., Gould, Stephen E., Low, Jennifer A., Rudin, Charles M., de Sauvage, Frederic J.

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Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer von Akdemir, Kadir C., Le, Victoria T., Chandran, Sahaana, Li, Yilong, Verhaak, Roel G., Beroukhim, Rameen, Campbell, Peter J., Chin, Lynda, Dixon, Jesse R., Futreal, P. Andrew

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Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19 von Druzak, Samuel, Iffrig, Elizabeth, Roberts, Blaine R., Zhang, Tiantian, Fibben, Kirby S., Sakurai, Yumiko, Verkerke, Hans P., Rostad, Christina A., Chahroudi, Ann, Schneider, Frank, Wong, Andrew Kam Ho, Roberts, Anne M., Chandler, Joshua D., Kim, Susan O., Mosunjac, Mario, Mosunjac, Marina, Geller, Rachel, Albizua, Igor, Stowell, Sean R., Arthur, Connie M., Anderson, Evan J., Ivanova, Anna A., Ahn, Jun, Liu, Xueyun, Maner-Smith, Kristal, Bowen, Thomas, Paiardini, Mirko, Bosinger, Steve E., Roback, John D., Kulpa, Deanna A., Silvestri, Guido, Lam, Wilbur A., Ortlund, Eric A., Maier, Cheryl L.

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The Molecular Taxonomy of Primary Prostate Cancer von Abeshouse, Adam, Akbani, Rehan, Ally, Adrian, Andry, Christopher D., Auman, J. Todd, Beroukhim, Rameen, Boutros, Paul C., Bradley, Robert K., Bristow, Christopher A., Bryce, Alan H., Butterfield, Yaron S.N., Button, Michael, Carroll, Peter R., Carter, Scott L., Carver, Brett S., Chan, June M., Chen, Yu, Cherniack, Andrew D., Cibulskis, Kristian, Ciriello, Giovanni, Costello, Anthony J., Dvinge, Heidi, Felau, Ina, Gardner, Johanna, Gehlenborg, Nils, Graefen, Markus, Guin, Ranabir, Gupta, Manaswi, Hadjipanayis, Angela, Hayes, D. Neil, Heiman, David I., Hoadley, Katherine A., Holbrook, Andrea H., Hoyle, Alan P., Huang, Mei, Ittmann, Michael, Kahles, Andre, Kane, Christopher J., Kerger, Michael, Klein, Robert J., Lai, Phillip H., Laird, Peter W., Lander, Eric S., Latour, Mathieu, Lawrence, Michael S., Lau, Kevin, LeBien, Tucker, Leraas, Kristen M., Lin, Pei, Linehan, W. Marston, Lolla, Laxmi, Longacre, Teri, Lu, Yiling, Mallery, David, Mariamidze, Armaz, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Mills, Gordon B., Minner, Sarah, Morrison, Carl, Naresh, Rashi, Nelson, Joel, Nelson, Peter S., Newton, Yulia, Noushmehr, Houtan, Parfenov, Michael, Park, Peter J., Piché, Alain, Rathmell, W. Kimryn, Reynolds, Sheila M., Roach, Jeffrey, Robertson, A. Gordon, Sadeghi, Sara, Scarlata, Eleonora, Shen, Ronglai, Shi, Yan, Shih, Juliann, Skelly, Tara, Sofia, Heidi J., Stewart, Chip, Sun, Charlie, Tan, Donghui, Taylor, Barry S., Teebagy, Patrick, Têtu, Bernard, Thiessen, Nina, Tirapelli, Daniela P., Tomlins, Scott A., Trevisan, Felipe Amstalden, True, Lawrence D., Weinhold, Nils, Wilkerson, Matthew D., Wu, Junyuan, Wu, Ye, Xu, Andrew W., Yadav, Shalini S., Yang, Lixing, Yena, Peggy, Zeng, Thomas

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Mitochondria Transplantation Mitigates Damage in an In Vitro Model of Renal Tubular Injury and in an Ex Vivo Model of DCD Renal Transplantation von Rossi, Andrea, Asthana, Amish, Riganti, Chiara, Sedrakyan, Sargis, Byers, Lori Nicole, Robertson, John, Senger, Ryan S., Montali, Filippo, Grange, Cristina, Dalmasso, Alessia, Porporato, Paolo E., Palles, Christina, Thornton, Matthew E, Da Sacco, Stefano, Perin, Laura, Ahn, Bumsoo, McCully, James, Orlando, Giuseppe, Bussolati, Benedetta

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Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration: A Mendelian Randomization Study von Kuan, Valerie, Warwick, Alasdair, Hingorani, Aroon, Tufail, Adnan, Cipriani, Valentina, Burgess, Stephen, Sofat, Reecha

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