Kynurenines: Tryptophan’s metabolites in exercise, inflammation, and mental health von Cervenka, Igor, Agudelo, Leandro Z., Ruas, Jorge L.

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Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression von Agudelo, Leandro Z., Femenía, Teresa, Orhan, Funda, Porsmyr-Palmertz, Margareta, Goiny, Michel, Martinez-Redondo, Vicente, Correia, Jorge C., Izadi, Manizheh, Bhat, Maria, Schuppe-Koistinen, Ina, Pettersson, Amanda T., Ferreira, Duarte M.S., Krook, Anna, Barres, Romain, Zierath, Juleen R., Erhardt, Sophie, Lindskog, Maria, Ruas, Jorge L.

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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation von Agudelo, Leandro Z., Ferreira, Duarte M.S., Cervenka, Igor, Bryzgalova, Galyna, Dadvar, Shamim, Jannig, Paulo R., Pettersson-Klein, Amanda T., Lakshmikanth, Tadepally, Sustarsic, Elahu G., Porsmyr-Palmertz, Margareta, Correia, Jorge C., Izadi, Manizheh, Martínez-Redondo, Vicente, Ueland, Per M., Midttun, Øivind, Gerhart-Hines, Zachary, Brodin, Petter, Pereira, Teresa, Berggren, Per-Olof, Ruas, Jorge L.

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Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance von Agudelo, Leandro Z., Ferreira, Duarte M. S., Dadvar, Shamim, Cervenka, Igor, Ketscher, Lars, Izadi, Manizheh, Zhengye, Liu, Furrer, Regula, Handschin, Christoph, Venckunas, Tomas, Brazaitis, Marius, Kamandulis, Sigitas, Lanner, Johanna T., Ruas, Jorge L.

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Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans von Schlittler, Maja, Goiny, Michel, Agudelo, Leandro Z, Venckunas, Tomas, Brazaitis, Marius, Skurvydas, Albertas, Kamandulis, Sigitas, Ruas, Jorge L, Erhardt, Sophie, Westerblad, Håkan, Andersson, Daniel C

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Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation von Mills, Richard, Taylor-Weiner, Hermes, Correia, Jorge C, Agudelo, Leandro Z, Allodi, Ilary, Kolonelou, Christina, Martinez-Redondo, Vicente, Ferreira, Duarte M S, Nichterwitz, Susanne, Comley, Laura H, Lundin, Vanessa, Hedlund, Eva, Ruas, Jorge L, Teixeira, Ana I

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LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force von Ferreira, Duarte M S, Cheng, Arthur J, Agudelo, Leandro Z, Cervenka, Igor, Chaillou, Thomas, Correia, Jorge C, Porsmyr-Palmertz, Margareta, Izadi, Manizheh, Hansson, Alicia, Martínez-Redondo, Vicente, Valente-Silva, Paula, Pettersson-Klein, Amanda T, Estall, Jennifer L, Robinson, Matthew M, Nair, K Sreekumaran, Lanner, Johanna T, Ruas, Jorge L

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Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments von Lopes, Noel, McIntyre, Claire, Martin, Stefania, Raverdeau, Mathilde, Sumaria, Nital, Kohlgruber, Ayano C., Fiala, Gina, Agudelo, Leandro Z., Dyck, Lydia, Kane, Harry, Douglas, Aaron, Cunningham, Stephen, Prendeville, Hannah, Loftus, Roisin, Carmody, Colleen, Pierre, Philippe, Kellis, Manolis, Brenner, Michael, Argüello, Rafael J., Silva-Santos, Bruno, Pennington, Daniel J., Lynch, Lydia

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Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells von Yang, Jiekun, Vamvini, Maria, Nigro, Pasquale, Ho, Li-Lun, Galani, Kyriakitsa, Alvarez, Marcus, Tanigawa, Yosuke, Renfro, Ashley, Carbone, Nicholas P., Laakso, Markku, Agudelo, Leandro Z., Pajukanta, Päivi, Hirshman, Michael F., Middelbeek, Roeland J.W., Grove, Kevin, Goodyear, Laurie J., Kellis, Manolis

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Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism von Correia, Jorge C, Massart, Julie, de Boer, Jan Freark, Porsmyr-Palmertz, Margareta, Martínez-Redondo, Vicente, Agudelo, Leandro Z, Sinha, Indranil, Meierhofer, David, Ribeiro, Vera, Björnholm, Marie, Sauer, Sascha, Dahlman-Wright, Karin, Zierath, Juleen R, Groen, Albert K, Ruas, Jorge L

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Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes von Martínez-Redondo, Vicente, Jannig, Paulo R., Correia, Jorge C., Ferreira, Duarte M.S., Cervenka, Igor, Lindvall, Jessica M., Sinha, Indranil, Izadi, Manizheh, Pettersson-Klein, Amanda T., Agudelo, Leandro Z., Gimenez-Cassina, Alfredo, Brum, Patricia C., Dahlman-Wright, Karin, Ruas, Jorge L.

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Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease von Linna-Kuosmanen, Suvi, Schmauch, Eloi, Galani, Kyriakitsa, Ojanen, Johannes, Boix, Carles A., Örd, Tiit, Toropainen, Anu, Singha, Prosanta K., Moreau, Pierre R., Harju, Kristiina, Blazeski, Adriana, Segerstolpe, Åsa, Lahtinen, Veikko, Hou, Lei, Kang, Kai, Meibalan, Elamaran, Agudelo, Leandro Z., Kokki, Hannu, Halonen, Jari, Jalkanen, Juho, Gunn, Jarmo, MacRae, Calum A., Hollmén, Maija, Hartikainen, Juha E.K., Kaikkonen, Minna U., García-Cardeña, Guillermo, Tavi, Pasi, Kiviniemi, Tuomas, Kellis, Manolis

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Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression von Agudelo, Leandro Z., Femenía, Teresa, Orhan, Funda, Porsmyr-Palmertz, Margareta, Goiny, Michel, Martinez-Redondo, Vicente, Correia, Jorge C., Izadi, Manizheh, Bhat, Maria, Schuppe-Koistinen, Ina, Pettersson, Amanda, Ferreira, Duarte M.S., Krook, Anna, Barres, Romain, Zierath, Juleen R., Erhardt, Sophie, Lindskog, Maria, Ruas, Jorge L.

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Skeletal muscle PGC-1α1 and KAT enzymes at the intersection between depression and metabolic disease von Agudelo, Leandro Z

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Symbiotic Cooperation for Web Agents: Harnessing Complementary Strengths of Large and Small LLMs von Zhang, Ruichen, Qiu, Mufan, Tan, Zhen, Zhang, Mohan, Lu, Vincent, Peng, Jie, Xu, Kaidi, Agudelo, Leandro Z, Qian, Peter, Chen, Tianlong

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Metabolic resilience is encoded in genome plasticity von Agudelo, Leandro Z., Tuyeres, Remy, Llinares, Claudia, Morcuende, Alvaro, Park, Yongjin, Sun, Na, Linna-Kuosmanen, Suvi, Atabaki-Pasdar, Naeimeh, Ho, Li-Lun, Galani, Kyriakitsa, Franks, Paul W., Kutlu, Burak, Grove, Kevin, Femenia, Teresa, Kellis, Manolis

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LIM and cysteine-rich domains 1 regulates skeletal muscle hypertrophy, calcium handling, and force von Ferreira, Duarte M. S, Cheng, Arthur J, Agudelo, Leandro Z, Cervenka, Igor, Chaillou, Thomas, Correia, Jorge C, Porsmyr-Palmertz, Margareta, Izadi, Manizheh, Hansson, Alicia, Martínez-Redondo, Vicente, Valente-Silva, Paula, Pettersson-Klein, Amanda T, Estall, Jennifer L, Robinson, Matthew M, Nair, K. Sreekumaran, Lanner, Johanna T, Ruas, Jorge L

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LIM and cysteine-rich domains 1 regulates skeletal muscle hypertrophy, calcium handling, and force von Ferreira, Duarte M. S, Cheng, Arthur J, Agudelo, Leandro Z, Cervenka, Igor, Chaillou, Thomas, Correia, Jorge C, Porsmyr-Palmertz, Margareta, Izadi, Manizheh, Hansson, Alicia, Martínez-Redondo, Vicente, Valente-Silva, Paula, Pettersson-Klein, Amanda T, Estall, Jennifer L, Robinson, Matthew M, Nair, K. Sreekumaran, Lanner, Johanna T, Ruas, Jorge L

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