Structure of a transcribing RNA polymerase II-U1 snRNP complex von Zhang, Suyang, Aibara, Shintaro, Vos, Seychelle M, Agafonov, Dmitry E, Lührmann, Reinhard, Cramer, Patrick

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Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation von Bertram, Karl, Agafonov, Dmitry E., Dybkov, Olexandr, Haselbach, David, Leelaram, Majety N., Will, Cindy L., Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

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Cryo-EM structure of a human spliceosome activated for step 2 of splicing von Bertram, Karl, Agafonov, Dmitry E., Liu, Wen-Ti, Dybkov, Olexandr, Will, Cindy L., Hartmuth, Klaus, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

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Structure and Conformational Dynamics of the Human Spliceosomal B act Complex von Haselbach, David, Komarov, Ilya, Agafonov, Dmitry E, Hartmuth, Klaus, Graf, Benjamin, Dybkov, Olexandr, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

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Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation von Townsend, Cole, Leelaram, Majety N, Agafonov, Dmitry E, Dybkov, Olexandr, Will, Cindy L, Bertram, Karl, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

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Molecular architecture of the human U4/U6.U5 tri-snRNP von Agafonov, Dmitry E., Kastner, Berthold, Dybkov, Olexandr, Hofele, Romina V., Liu, Wen-Ti, Urlaub, Henning, Lührmann, Reinhard, Stark, Holger

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Molecular architecture of the human 17S U2 snRNP von Zhang, Zhenwei, Will, Cindy L., Bertram, Karl, Dybkov, Olexandr, Hartmuth, Klaus, Agafonov, Dmitry E., Hofele, Romina, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

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Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes von Schneider, Cornelius, Agafonov, Dmitry E, Schmitzová, Jana, Hartmuth, Klaus, Fabrizio, Patrizia, Lührmann, Reinhard

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A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity von Boesler, Carsten, Rigo, Norbert, Anokhina, Maria M., Tauchert, Marcel J., Agafonov, Dmitry E., Kastner, Berthold, Urlaub, Henning, Ficner, Ralf, Will, Cindy L., Lührmann, Reinhard

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Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method von Agafonov, Dmitry E., Deckert, Jochen, Wolf, Elmar, Odenwälder, Peter, Bessonov, Sergey, Will, Cindy L., Urlaub, Henning, Lührmann, Reinhard

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Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome von Bertram, Karl, El Ayoubi, Leyla, Dybkov, Olexandr, Agafonov, Dmitry E., Will, Cindy L., Hartmuth, Klaus, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

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Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells von Alló, Mariano, Agirre, Eneritz, Bessonov, Sergey, Bertucci, Paola, Acuña, Luciana Gómez, Buggiano, Valeria, Bellora, Nicolás, Singh, Babita, Petrillo, Ezequiel, Blaustein, Matías, Miñana, Belén, Dujardin, Gwendal, Pozzi, Berta, Pelisch, Federico, Bechara, Elías, Agafonov, Dmitry E., Srebrow, Anabella, Lührmann, Reinhard, Valcárcel, Juan, Eyras, Eduardo, Kornblihtt, Alberto R.

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Molecular Architecture of the Human Prp19/CDC5L Complex von Grote, Michael, Wolf, Elmar, Will, Cindy L., Lemm, Ira, Agafonov, Dmitry E., Schomburg, Adrian, Fischle, Wolfgang, Urlaub, Henning, Lührmann, Reinhard

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The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction von Fourmann, Jean-Baptiste, Dybkov, Olexandr, Agafonov, Dmitry E, Tauchert, Marcel J, Urlaub, Henning, Ficner, Ralf, Fabrizio, Patrizia, Lührmann, Reinhard

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Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation von Sidarovich, Anzhalika, Will, Cindy L, Anokhina, Maria M, Ceballos, Javier, Sievers, Sonja, Agafonov, Dmitry E, Samatov, Timur, Bao, Penghui, Kastner, Berthold, Urlaub, Henning, Waldmann, Herbert, Lührmann, Reinhard

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Phase-Homogeneous LiFePO4 Powders with Crystallites Protected by Ferric-Graphite-Graphene Composite von Agafonov, Dmitry, Bobyl, Aleksandr, Kamzin, Aleksandr, Nashchekin, Alexey, Ershenko, Evgeniy, Ushakov, Arseniy, Kasatkin, Igor, Levitskii, Vladimir, Trenikhin, Mikhail, Terukov, Evgeniy

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Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex von Haselbach, David, Komarov, Ilya, Agafonov, Dmitry E., Hartmuth, Klaus, Graf, Benjamin, Dybkov, Olexandr, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

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ATPγS stalls splicing after B complex formation but prior to spliceosome activation von Agafonov, Dmitry E, van Santen, Marieke, Kastner, Berthold, Dube, Prakash, Will, Cindy L, Urlaub, Henning, Lührmann, Reinhard

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Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site von Boesler, Carsten, Rigo, Norbert, Agafonov, Dmitry E, Kastner, Berthold, Urlaub, Henning, Will, Cindy L, Lührmann, Reinhard

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Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C proteins von Dybkov, Olexandr, Preußner, Marco, El Ayoubi, Leyla, Feng, Vivi-Yun, Harnisch, Caroline, Merz, Kilian, Leupold, Paula, Yudichev, Peter, Agafonov, Dmitry E, Will, Cindy L, Girard, Cyrille, Dienemann, Christian, Urlaub, Henning, Kastner, Berthold, Heyd, Florian, Lührmann, Reinhard

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