Structure and Conformational Dynamics of the Human Spliceosomal B act Complex von Haselbach, David, Komarov, Ilya, Agafonov, Dmitry E, Hartmuth, Klaus, Graf, Benjamin, Dybkov, Olexandr, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

Volltext

Structure of a transcribing RNA polymerase II-U1 snRNP complex von Zhang, Suyang, Aibara, Shintaro, Vos, Seychelle M, Agafonov, Dmitry E, Lührmann, Reinhard, Cramer, Patrick

Volltext

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation von Bertram, Karl, Agafonov, Dmitry E., Dybkov, Olexandr, Haselbach, David, Leelaram, Majety N., Will, Cindy L., Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

Volltext

ATPγS stalls splicing after B complex formation but prior to spliceosome activation von Agafonov, Dmitry E, van Santen, Marieke, Kastner, Berthold, Dube, Prakash, Will, Cindy L, Urlaub, Henning, Lührmann, Reinhard

Volltext

Cryo-EM structure of a human spliceosome activated for step 2 of splicing von Bertram, Karl, Agafonov, Dmitry E., Liu, Wen-Ti, Dybkov, Olexandr, Will, Cindy L., Hartmuth, Klaus, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

Volltext

Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site von Boesler, Carsten, Rigo, Norbert, Agafonov, Dmitry E, Kastner, Berthold, Urlaub, Henning, Will, Cindy L, Lührmann, Reinhard

Volltext

Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation von Townsend, Cole, Leelaram, Majety N, Agafonov, Dmitry E, Dybkov, Olexandr, Will, Cindy L, Bertram, Karl, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

Volltext

Molecular architecture of the human U4/U6.U5 tri-snRNP von Agafonov, Dmitry E., Kastner, Berthold, Dybkov, Olexandr, Hofele, Romina V., Liu, Wen-Ti, Urlaub, Henning, Lührmann, Reinhard, Stark, Holger

Volltext

Molecular architecture of the human 17S U2 snRNP von Zhang, Zhenwei, Will, Cindy L., Bertram, Karl, Dybkov, Olexandr, Hartmuth, Klaus, Agafonov, Dmitry E., Hofele, Romina, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

Volltext

Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes von Schneider, Cornelius, Agafonov, Dmitry E, Schmitzová, Jana, Hartmuth, Klaus, Fabrizio, Patrizia, Lührmann, Reinhard

Volltext

Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome von Bertram, Karl, El Ayoubi, Leyla, Dybkov, Olexandr, Agafonov, Dmitry E., Will, Cindy L., Hartmuth, Klaus, Urlaub, Henning, Kastner, Berthold, Stark, Holger, Lührmann, Reinhard

Volltext

A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity von Boesler, Carsten, Rigo, Norbert, Anokhina, Maria M., Tauchert, Marcel J., Agafonov, Dmitry E., Kastner, Berthold, Urlaub, Henning, Ficner, Ralf, Will, Cindy L., Lührmann, Reinhard

Volltext

Semiquantitative Proteomic Analysis of the Human Spliceosome via a Novel Two-Dimensional Gel Electrophoresis Method von Agafonov, Dmitry E., Deckert, Jochen, Wolf, Elmar, Odenwälder, Peter, Bessonov, Sergey, Will, Cindy L., Urlaub, Henning, Lührmann, Reinhard

Volltext

Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells von Alló, Mariano, Agirre, Eneritz, Bessonov, Sergey, Bertucci, Paola, Acuña, Luciana Gómez, Buggiano, Valeria, Bellora, Nicolás, Singh, Babita, Petrillo, Ezequiel, Blaustein, Matías, Miñana, Belén, Dujardin, Gwendal, Pozzi, Berta, Pelisch, Federico, Bechara, Elías, Agafonov, Dmitry E., Srebrow, Anabella, Lührmann, Reinhard, Valcárcel, Juan, Eyras, Eduardo, Kornblihtt, Alberto R.

Volltext

Molecular Architecture of the Human Prp19/CDC5L Complex von Grote, Michael, Wolf, Elmar, Will, Cindy L., Lemm, Ira, Agafonov, Dmitry E., Schomburg, Adrian, Fischle, Wolfgang, Urlaub, Henning, Lührmann, Reinhard

Volltext

Efficient suppression of the amber codon in E. coli in vitro translation system von Agafonov, Dmitry E., Huang, Yiwei, Grote, Michael, Sprinzl, Mathias

Volltext

The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction von Fourmann, Jean-Baptiste, Dybkov, Olexandr, Agafonov, Dmitry E, Tauchert, Marcel J, Urlaub, Henning, Ficner, Ralf, Fabrizio, Patrizia, Lührmann, Reinhard

Volltext

Identification of a small molecule inhibitor that stalls splicing at an early step of spliceosome activation von Sidarovich, Anzhalika, Will, Cindy L, Anokhina, Maria M, Ceballos, Javier, Sievers, Sonja, Agafonov, Dmitry E, Samatov, Timur, Bao, Penghui, Kastner, Berthold, Urlaub, Henning, Waldmann, Herbert, Lührmann, Reinhard

Volltext

Phase-Homogeneous LiFePO4 Powders with Crystallites Protected by Ferric-Graphite-Graphene Composite von Agafonov, Dmitry, Bobyl, Aleksandr, Kamzin, Aleksandr, Nashchekin, Alexey, Ershenko, Evgeniy, Ushakov, Arseniy, Kasatkin, Igor, Levitskii, Vladimir, Trenikhin, Mikhail, Terukov, Evgeniy

Volltext

Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex von Haselbach, David, Komarov, Ilya, Agafonov, Dmitry E., Hartmuth, Klaus, Graf, Benjamin, Dybkov, Olexandr, Urlaub, Henning, Kastner, Berthold, Lührmann, Reinhard, Stark, Holger

Volltext