Endothelial TLR4 activation impairs intestinal microcirculatory perfusion in necrotizing enterocolitis via eNOS–NO–nitrite signaling von Yazji, Ibrahim, Sodhi, Chhinder P., Lee, Elizabeth K., Good, Misty, Egan, Charlotte E., Afrazi, Amin, Neal, Matthew D., Jia, Hongpeng, Lin, Joyce, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Richardson, Ward M., Ozolek, John, Billiar, Timothy R., Binion, David G., Gladwin, Mark T., Hackam, David J.

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Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis von Afrazi, Amin, Branca, Maria F., Sodhi, Chhinder P., Good, Misty, Yamaguchi, Yukihiro, Egan, Charlotte E., Lu, Peng, Jia, Hongpeng, Shaffiey, Shahab, Lin, Joyce, Ma, Congrong, Vincent, Garrett, Thomas, Prindle, Weyandt, Samantha, Neal, Matthew D., Ozolek, John A., Wiersch, John, Tschurtschenthaler, Markus, Shiota, Chiyo, Gittes, George K., Billiar, Timothy R., Mollen, Kevin, Kaser, Arthur, Blumberg, Richard, Hackam, David J.

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Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors von Neal, Matthew D, Jia, Hongpeng, Eyer, Benjamin, Good, Misty, Guerriero, Christopher J, Sodhi, Chhinder P, Afrazi, Amin, Prindle, Jr, Thomas, Ma, Congrong, Branca, Maria, Ozolek, John, Brodsky, Jeffrey L, Wipf, Peter, Hackam, David J

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A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis von Neal, Matthew D, Sodhi, Chhinder P, Dyer, Mitchell, Craig, Brian T, Good, Misty, Jia, Hongpeng, Yazji, Ibrahim, Afrazi, Amin, Richardson, Ward M, Beer-Stolz, Donna, Ma, Congrong, Prindle, Thomas, Grant, Zachary, Branca, Maria F, Ozolek, John, Hackam, David J

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Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium von Good, Misty, Siggers, Richard H, Sodhi, Chhinder P, Afrazi, Amin, Alkhudari, Feras, Egan, Charlotte E, Neal, Matthew D, Yazji, Ibrahim, Jia, Hongpeng, Lin, Joyce, Branca, Maria F, Ma, Congrong, Prindle, Thomas, Grant, Zachary, Shah, Sapana, Slagle, Dennis, Paredes, Jose, Ozolek, John, Gittes, George K, Hackam, David J

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Innate Immune Signaling in the Pathogenesis of Necrotizing Enterocolitis von Sodhi, Chhinder P., Good, Misty, Afrazi, Amin, Hackam, David J.

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Differential effects of diesel exhaust particles on T cell differentiation and autoimmune disease von O'Driscoll, Chelsea A, Owens, Leah A, Gallo, Madeline E, Hoffmann, Erica J, Afrazi, Amin, Han, Mei, Fechner, John H, Schauer, James J, Bradfield, Christopher A, Mezrich, Joshua D

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Intracellular heat shock protein-70 negatively regulates TLR4 signaling in the newborn intestinal epithelium von Afrazi, Amin, Sodhi, Chhinder P, Good, Misty, Jia, Hongpeng, Siggers, Richard, Yazji, Ibrahim, Ma, Congrong, Neal, Matthew D, Prindle, Thomas, Grant, Zachary S, Branca, Maria F, Ozolek, John, Chang, Eugene B, Hackam, David J

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Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B von Kaczorowski, David J, Scott, Melanie J, Pibris, John P, Afrazi, Amin, Nakao, Atsunori, Edmonds, Rebecca D, Kim, Sodam, Kwak, Joon H, Liu, Yujian, Fan, Jie, Billiar, Timothy R

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Pivotal Advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but... von Kaczorowski, David J., Afrazi, Amin, Scott, Melanie J., Kwak, Joon H., Gill, Roop, Edmonds, Rebecca D., Liu, Yujian, Fan, Jie, Billiar, Timothy R.

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Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal gr... von Good, M, Sodhi, C P, Egan, C E, Afrazi, A, Jia, H, Yamaguchi, Y, Lu, P, Branca, M F, Ma, C, Prindle, T, Mielo, S, Pompa, A, Hodzic, Z, Ozolek, J A, Hackam, D J

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Intestinal Epithelial Toll-Like Receptor 4 Regulates Goblet Cell Development and Is Required for Necrotizing Enterocolitis in Mice von Sodhi, Chhinder P, Neal, Matthew D, Siggers, Richard, Sho, Shonan, Ma, Congrong, Branca, Maria F, Prindle, Thomas, Russo, Anthony M, Afrazi, Amin, Good, Misty, Brower–Sinning, Rachel, Firek, Brian, Morowitz, Michael J, Ozolek, John A, Gittes, George K, Billiar, Timothy R, Hackam, David J

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Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis von Neal, Matthew D., Sodhi, Chhinder P., Jia, Hongpeng, Dyer, Mitchell, Egan, Charlotte E., Yazji, Ibrahim, Good, Misty, Afrazi, Amin, Marino, Ryan, Slagle, Dennis, Ma, Congrong, Branca, Maria F., Prindle, Thomas, Grant, Zachary, Ozolek, John, Hackam, David J.

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Gut Symbionts Lactobacillus reuteri R2lc and 2010 Encode a Polyketide Synthase Cluster That Activates the Mammalian Aryl Hydrocarbon Receptor von Özçam, Mustafa, Tocmo, Restituto, Oh, Jee-Hwan, Afrazi, Amin, Mezrich, Joshua D, Roos, Stefan, Claesen, Jan, van Pijkeren, Jan-Peter

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Cavitary lung lesions and pneumothorax in a healthy patient with active coronavirus-19 (COVID-19) viral pneumonia von Afrazi, Amin, Garcia-Rodriguez, Sylvana, Maloney, James D, Morgan, Clinton T

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New Insights Into the Pathogenesis and Treatment of Necrotizing Enterocolitis: Toll-Like Receptors and Beyond von Afrazi, Amin, Sodhi, Chhinder P, Richardson, Ward, Neal, Matthew, Good, Misty, Siggers, Richard, Hackam, David J

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Ambient urban dust particulate matter reduces pathologic T cells in the CNS and severity of EAE von O’Driscoll, Chelsea A., Owens, Leah A., Hoffmann, Erica J., Gallo, Madeline E., Afrazi, Amin, Han, Mei, Fechner, John H., Schauer, James J., Bradfield, Christopher A., Mezrich, Joshua D.

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Understanding the Value of Tumor Markers in Pediatric Ovarian Neoplasms von Lawrence, Amy E., Fallat, Mary E., Hewitt, Geri, Hertweck, Paige, Onwuka, Amanda, Afrazi, Amin, Bence, Christina, Burns, Robert C., Corkum, Kristine S., Dillon, Patrick A., Ehrlich, Peter F., Fraser, Jason D., Gonzalez, Dani O., Grabowski, Julia E., Kabre, Rashmi, Lal, Dave R., Landman, Matthew P., Leys, Charles M., Mak, Grace Z., Overman, R. Elliott, Rademacher, Brooks L., Raiji, Manish T., Sato, Thomas T., Scannell, Madeline, Sujka, Joseph A., Wright, Tiffany, Minneci, Peter C., Deans, Katherine J., Aldrink, Jennifer H.

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Can fecal continence be predicted in patients born with anorectal malformations? von Minneci, Peter C., Kabre, Rashmi S., Mak, Grace Z., Halleran, Devin R., Cooper, Jennifer N., Afrazi, Amin, Calkins, Casey M., Corkum, Kristine, Downard, Cynthia D., Ehrlich, Peter, Fraser, Jason D., Gadepalli, Samir K., Helmrath, Michael A., Kohler, Jonathan E., Landisch, Rachel, Landman, Matthew P., Lee, Constance, Leys, Charles M, Lodwick, Daniel L., McLeod, Jennifer, Mon, Rodrigo, McClure, Beth, Rymeski, Beth, Saito, Jacqueline M., Sato, Thomas T., St. Peter, Shawn D., Wood, Richard, Levitt, Marc A., Deans, Katherine J.

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Nucleotide-Binding Oligomerization Domain-2 Inhibits Toll-Like Receptor-4 Signaling in the Intestinal Epithelium von Richardson, Ward M, Sodhi, Chhinder P, Russo, Anthony, Siggers, Richard H, Afrazi, Amin, Gribar, Steven C, Neal, Matthew D, Dai, Shipan, Prindle, Thomas, Branca, Maria, Ma, Congrong, Ozolek, John, Hackam, David J

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