A CRISPR/Cas9 engineered MplS504N mouse model recapitulates human myelofibrosis von Adriaanse, Fabienne R. S., Kamens, Jennifer L., Vogel, Peter, Sakurada, Sadie M., Pruett-Miller, Shondra M., Stam, Ronald W., Michel Zwaan, C., Gruber, Tanja A.

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Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A -Rearranged Acute Lymphoblastic and Myeloid Leukemia von Adriaanse, Fabienne R S, Schneider, Pauline, Arentsen-Peters, Susan T C J M, Fonseca, Ana M Neves da, Stutterheim, Janine, Pieters, Rob, Zwaan, C Michel, Stam, Ronald W

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CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in KMT2A-Rearranged Acute Lymphoblastic Leukemia von Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M., Vrenken, Kirsten S., Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S., Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W.

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Modelling acquired resistance to DOT1L inhibition exhibits the adaptive potential of KMT2A-rearranged acute lymphoblastic leukemia von Schneider, Pauline, Crump, Nicholas T, Arentsen-Peters, Susan T C J M, Smith, Alastair L, Hagelaar, Rico, Adriaanse, Fabienne R S, Bos, Romy S, de Jong, Anja, Nierkens, Stefan, Koopmans, Bianca, Milne, Thomas A, Pieters, Rob, Stam, Ronald W

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A convergent malignant phenotype in B-cell acute lymphoblastic leukemia involving the splicing factor SRRM1 von Closa, Adria, Reixachs-Solé, Marina, Fuentes-Fayos, Antonio C, Hayer, Katharina E, Melero, Juan L, Adriaanse, Fabienne R S, Bos, Romy S, Torres-Diz, Manuel, Hunger, Stephen P, Roberts, Kathryn G, Mullighan, Charles G, Stam, Ronald W, Thomas-Tikhonenko, Andrei, Castaño, Justo P, Luque, Raúl M, Eyras, Eduardo

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CRISPR-Cas9 Library Screening Identifies Novel Molecular Vulnerabilities in IKMT2A/I-Rearranged Acute Lymphoblastic Leukemia von Schneider, Pauline, Wander, Priscilla, Arentsen-Peters, Susan T. C. J. M, Vrenken, Kirsten S, Rockx-Brouwer, Dedeke, Adriaanse, Fabienne R. S, Hoeve, Veerle, Paassen, Irene, Drost, Jarno, Pieters, Rob, Stam, Ronald W

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