New Modalities for Challenging Targets in Drug Discovery von Valeur, Eric, Guéret, Stéphanie M., Adihou, Hélène, Gopalakrishnan, Ranganath, Lemurell, Malin, Waldmann, Herbert, Grossmann, Tom N., Plowright, Alleyn T.

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Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket von Karatas, Hacer, Akbarzadeh, Mohammad, Adihou, Hélène, Hahne, Gernot, Pobbati, Ajaybabu V, Yihui Ng, Elizabeth, Guéret, Stéphanie M, Sievers, Sonja, Pahl, Axel, Metz, Malte, Zinken, Sarah, Dötsch, Lara, Nowak, Christine, Thavam, Sasikala, Friese, Alexandra, Kang, CongBao, Hong, Wanjin, Waldmann, Herbert

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Combining Real-Time Monitoring Using Raman Spectroscopy, Rotating-Bed Reactors, and Green Solvents to Improve Sustainability in Solid-Phase Peptide Synthesis von Fournier, Eugenie, Vijeta, Arjun, Babii, Oleg, Wawi, Mohamad-Jamal, Henkel, Bernd, Adihou, Hélène

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TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics von Kunig, Verena B. K., Potowski, Marco, Akbarzadeh, Mohammad, Klika Škopić, Mateja, Santos Smith, Denise, Arendt, Lukas, Dormuth, Ina, Adihou, Hélène, Andlovic, Blaž, Karatas, Hacer, Shaabani, Shabnam, Zarganes‐Tzitzikas, Tryfon, Neochoritis, Constantinos G., Zhang, Ran, Groves, Matthew, Guéret, Stéphanie M., Ottmann, Christian, Rahnenführer, Jörg, Fried, Roland, Dömling, Alexander, Brunschweiger, Andreas

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A protein tertiary structure mimetic modulator of the Hippo signalling pathway von Adihou, Hélène, Gopalakrishnan, Ranganath, Förster, Tim, Guéret, Stéphanie M., Gasper, Raphael, Geschwindner, Stefan, Carrillo García, Carmen, Karatas, Hacer, Pobbati, Ajaybabu V., Vazquez‐Chantada, Mercedes, Davey, Paul, Wassvik, Carola M., Pang, Jeremy Kah Sheng, Soh, Boon Seng, Hong, Wanjin, Chiarparin, Elisabetta, Schade, Dennis, Plowright, Alleyn T., Valeur, Eric, Lemurell, Malin, Grossmann, Tom N., Waldmann, Herbert

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A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters von Terrier, Victor P, Adihou, Hélène, Arnould, Mathieu, Delmas, Agnès F, Aucagne, Vincent

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Biosynthesis of the Antibiotic Nematophin and Its Elongated Derivatives in Entomopathogenic Bacteria von Cai, Xiaofeng, Challinor, Victoria L, Zhao, Lei, Reimer, Daniela, Adihou, Hélène, Grün, Peter, Kaiser, Marcel, Bode, Helge B

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Hot-spot guided design of macrocyclic inhibitors of the LSD1-CoREST1 interaction von ‘T Hart, Peter, Openy, Joseph, Krzyzanowski, Adrian, Adihou, Hélène, Waldmann, Herbert

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Combined Approach of Backbone Amide Linking and On-Resin N‑Methylation for the Synthesis of Bioactive and Metabolically Stable Peptides von Wesche, Frank, Adihou, Hélène, Kaiser, Astrid, Wurglics, Mario, Schubert-Zsilavecz, Manfred, Kaiser, Marcel, Bode, Helge B

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Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5–MEP50 Complex von Krzyzanowski, Adrian, Gasper, Raphael, Adihou, Hélène, Hart, Peter 't, Waldmann, Herbert

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Selective Fluorescent Nonpeptidic Antagonists For Vasopressin V2 GPCR: Application To Ligand Screening and Oligomerization Assays von Loison, Stéphanie, Cottet, Martin, Orcel, Hélène, Adihou, Hélène, Rahmeh, Rita, Lamarque, Laurent, Trinquet, Eric, Kellenberger, Esther, Hibert, Marcel, Durroux, Thierry, Mouillac, Bernard, Bonnet, Dominique

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Synthesis and SAR of the antistaphylococcal natural product nematophin from Xenorhabdus nematophila von Wesche, Frank, Adihou, Hélène, Wichelhaus, Thomas A, Bode, Helge B

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Structure Based Design of Bicyclic Peptide Inhibitors of RbAp48 von Hart, Peter 't, Hommen, Pascal, Noisier, Anaïs, Krzyzanowski, Adrian, Schüler, Darijan, Porfetye, Arthur T., Akbarzadeh, Mohammad, Vetter, Ingrid R., Adihou, Hélène, Waldmann, Herbert

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Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations von Sampson, Jared M., Cannon, Daniel A., Duan, Jianxin, Epstein, Jordan C.K., Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha M., Bahna, Fabiana A., Adihou, Hélène, Guéret, Stéphanie M., Gopalakrishnan, Ranganath, Geschwindner, Stefan, Rees, D. Gareth, Sigurdardottir, Anna, Wilkinson, Trevor, Dodd, Roger B., De Maria, Leonardo, Mobarec, Juan Carlos, Shapiro, Lawrence, Honig, Barry, Buchanan, Andrew, Friesner, Richard A., Wang, Lingle

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Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments von Raibaut, Laurent, Adihou, Hélène, Desmet, Rémi, Delmas, Agnès F., Aucagne, Vincent, Melnyk, Oleg

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Structure, Biosynthesis, and Occurrence of Bacterial Pyrrolizidine Alkaloids von Schimming, Olivia, Challinor, Victoria L., Tobias, Nicholas J., Adihou, Hélène, Grün, Peter, Pöschel, Laura, Richter, Christian, Schwalbe, Harald, Bode, Helge B.

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Molecular mechanism of polyketide shortening in anthraquinone biosynthesis of Photorhabdus luminescens von Zhou, Qiuqin, Bräuer, Alois, Adihou, Hélène, Schmalhofer, Maximilian, Saura, Patricia, Grammbitter, Gina L C, Kaila, Ville R I, Groll, Michael, Bode, Helge B

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Solid-Phase Enrichment and Analysis of Azide-Labeled Natural Products: Fishing Downstream of Biochemical Pathways von Pérez, Alexander J., Wesche, Frank, Adihou, Hélène, Bode, Helge B.

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Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 von Cromm, Philipp M., Adihou, Hélène, Kapoor, Shobhna, Vazquez‐Chantada, Mercedes, Davey, Paul, Longmire, David, Hennes, Elisabeth, Hofer, Walter, Küchler, Philipp, Chiarparin, Elisabetta, Waldmann, Herbert, Grossmann, Tom N.

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Synthesis of Peptides by Reactive Extrusion. Application to the Continuous and Solventless Preparation of Aspartame von Mohy El‐Dine, Tharwat, Lavayssiere, Matthieu, Adihou, Hélène, Subra, Gilles, Métro, Thomas‐Xavier, Ludemann‐Hombourger, Olivier, Lamaty, Frédéric

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