CRISPR screens in physiologic medium reveal conditionally essential genes in human cells von Rossiter, Nicholas J, Huggler, Kimberly S, Adelmann, Charles H, Keys, Heather R, Soens, Ross W, Sabatini, David M, Cantor, Jason R

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Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery von Boehnke, Natalie, Straehla, Joelle P, Safford, Hannah C, Kocak, Mustafa, Rees, Matthew G, Ronan, Melissa, Rosenberg, Danny, Adelmann, Charles H, Chivukula, Raghu R, Nabar, Namita, Berger, Adam G, Lamson, Nicholas G, Cheah, Jaime H, Li, Hojun, Roth, Jennifer A, Koehler, Angela N, Hammond, Paula T

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Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction von Condon, Kendall J., Orozco, Jose M., Adelmann, Charles H., Spinelli, Jessica B., van der Helm, Pim W., Roberts, Justin M., Kunchok, Tenzin, Sabatini, David M.

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Advances in Inhaled Technologies: Understanding the Therapeutic Challenge, Predicting Clinical Performance, and Designing the Optimal Inhaled Product von Bäckman, P, Adelmann, H, Petersson, G, Jones, C B

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Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates von Chitsazzadeh, Vida, Coarfa, Cristian, Drummond, Jennifer A., Nguyen, Tri, Joseph, Aaron, Chilukuri, Suneel, Charpiot, Elizabeth, Adelmann, Charles H., Ching, Grace, Nguyen, Tran N., Nicholas, Courtney, Thomas, Valencia D., Migden, Michael, MacFarlane, Deborah, Thompson, Erika, Shen, Jianjun, Takata, Yoko, McNiece, Kayla, Polansky, Maxim A., Abbas, Hussein A., Rajapakshe, Kimal, Gower, Adam, Spira, Avrum, Covington, Kyle R., Xiao, Weimin, Gunaratne, Preethi, Pickering, Curtis, Frederick, Mitchell, Myers, Jeffrey N., Shen, Li, Yao, Hui, Su, Xiaoping, Rapini, Ronald P., Wheeler, David A., Hawk, Ernest T., Flores, Elsa R., Tsai, Kenneth Y.

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MFSD12 mediates the import of cysteine into melanosomes and lysosomes von Adelmann, Charles H., Traunbauer, Anna K., Chen, Brandon, Condon, Kendall J., Chan, Sze Ham, Kunchok, Tenzin, Lewis, Caroline A., Sabatini, David M.

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A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis von Yoon, Sung-Hee, Meyer, Mark B, Arevalo, Carlos, Tekguc, Murat, Zhang, Chengcheng, Wang, Jialiang S, Castro Andrade, Christian D, Strauss, Katelyn, Sato, Tadatoshi, Benkusky, Nancy A, Lee, Seong Min, Berdeaux, Rebecca, Foretz, Marc, Sundberg, Thomas B, Xavier, Ramnik J, Adelmann, Charles H, Brooks, Daniel J, Anselmo, Anthony, Sadreyev, Ruslan I, Rosales, Ivy A, Fisher, David E, Gupta, Navin, Morizane, Ryuji, Greka, Anna, Pike, J Wesley, Mannstadt, Michael, Wein, Marc N

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MFN2 Stabilization: A Bridge for Endoplasmic Reticulum Stress Sensitivity in Melanoma von Adelmann, Charles H., Rachmin, Inbal, Fisher, David E.

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Sorafenib suppresses JNK-dependent apoptosis through inhibition of ZAK von Vin, Harina, Ching, Grace, Ojeda, Sandra S, Adelmann, Charles H, Chitsazzadeh, Vida, Dwyer, David W, Ma, Haiching, Ehrenreiter, Karin, Baccarini, Manuela, Ruggieri, Rosamaria, Curry, Jonathan L, Ciurea, Ana M, Duvic, Madeleine, Busaidy, Naifa L, Tannir, Nizar M, Tsai, Kenneth Y

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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer von Weiss-Sadan, Tommy, Ge, Maolin, Hayashi, Makiko, Gohar, Magdy, Yao, Cong-Hui, de Groot, Adriaan, Harry, Stefan, Carlin, Alexander, Fischer, Hannah, Shi, Lei, Wei, Ting-Yu, Adelmann, Charles H., Wolf, Konstantin, Vornbäumen, Tristan, Dürr, Benedikt R., Takahashi, Mariko, Richter, Marianne, Zhang, Junbing, Yang, Tzu-Yi, Vijay, Vindhya, Fisher, David E., Hata, Aaron N., Haigis, Marcia C., Mostoslavsky, Raul, Bardeesy, Nabeel, Papagiannakopoulos, Thales, Bar-Peled, Liron

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Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines von Adelmann, Charles H., Wang, Tim, Sabatini, David M., Lander, Eric S.

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miR-181a Promotes Multiple Protumorigenic Functions by Targeting TGFβR3 von Chitsazzadeh, Vida, Nguyen, Tran N., de Mingo Pulido, Alvaro, Bittencourt, Bruna B., Du, Lili, Adelmann, Charles H., Ortiz Rivera, Ivannie, Nguyen, Kimberly A., Guerra, Leah D., Davis, Andrew, Napoli, Marco, Ma, Wencai, Davis, Richard Eric, Rajapakshe, Kimal, Coarfa, Cristian, Flores, Elsa R., Tsai, Kenneth Y.

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NRF2 activation induces NADH-reductive stress, providing a metabolic vulnerability in lung cancer von Weiss-Sadan, Tommy, Ge, Maolin, Hayashi, Makiko, Gohar, Magdy, Yao, Cong-Hui, de Groot, Adriaan, Harry, Stefan, Carlin, Alexander, Fischer, Hannah, Shi, Lei, Wei, Ting-Yu, Adelmann, Charles H., Wolf, Konstantin, Vornbäumen, Tristan, Dürr, Benedikt R., Takahashi, Mariko, Richter, Marianne, Zhang, Junbing, Yang, Tzu-Yi, Vijay, Vindhya, Fisher, David E., Hata, Aaron N., Haigis, Marcia C., Mostoslavsky, Raul, Bardeesy, Nabeel, Papagiannakopoulos, Thales, Bar-Peled, Liron

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Comparative profiles of BRAF inhibitors: the paradox index as a predictor of clinical toxicity von Adelmann, Charles H, Ching, Grace, Du, Lili, Saporito, Rachael C, Bansal, Varun, Pence, Lindy J, Liang, Roger, Lee, Woojin, Tsai, Kenneth Y

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Noninvasive Assessment of Epidermal Genomic Markers of UV Exposure in Skin von Muradova, Elnara, Patel, Nishit, Sell, Brittney, Bittencourt, Bruna B., Ojeda, Sandra S., Adelmann, Charles H., Cen, Ling, Cheng, Chia-Ho, Shen, Jianjun, Davis, Christel M., Ehli, Erik A., Newberg, Justin Y., Cherpelis, Basil, Black, Michael A., Mann, Michael B., Mitragotri, Samir, Tsai, Kenneth Y.

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BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling von Vin, Harina, Ojeda, Sandra S, Ching, Grace, Leung, Marco L, Chitsazzadeh, Vida, Dwyer, David W, Adelmann, Charles H, Restrepo, Monica, Richards, Kristen N, Stewart, Larissa R, Du, Lili, Ferguson, Scarlett B, Chakravarti, Deepavali, Ehrenreiter, Karin, Baccarini, Manuela, Ruggieri, Rosamaria, Curry, Jonathan L, Kim, Kevin B, Ciurea, Ana M, Duvic, Madeleine, Prieto, Victor G, Ullrich, Stephen E, Dalby, Kevin N, Flores, Elsa R, Tsai, Kenneth Y

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Butterworth equations for homomorphic filtering of images von Adelmann, Holger G

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Abstract 43: MicroRNA-130b mediates a metabolic switch to promote cutaneous squamous cell carcinoma development von Nguyen, Tran N., Moyer, Sydney, Adelmann, Charles H., Chitsazzadeh, Vida, Tsai, Kenneth Y.

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MEK Is a Therapeutic and Chemopreventative Target in Squamous Cell Carcinoma von Adelmann, Charles H., Truong, Kimberly A., Liang, Roger J., Bansal, Varun, Gandee, Leah, Saporito, Rachael C., Lee, Woojin, Du, Lili, Nicholas, Courtney, Napoli, Marco, Mino, Barbara, South, Andrew P., Proby, Charlotte M., Leigh, Irene M., Coarfa, Cristian, Flores, Elsa R., Tsai, Kenneth Y.

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Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine von Warthaka, Mangalika, Adelmann, Charles H, Kaoud, Tamer S, Edupuganti, Ramakrishna, Yan, Chunli, Johnson, William H, Ferguson, Scarlett, Tavares, Clint D, Pence, Lindy J, Anslyn, Eric V, Ren, Pengyu, Tsai, Kenneth Y, Dalby, Kevin N

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