Re-structuring hedges: Rejuvenation management can improve the long term quality of hedgerow habitats for wildlife in the UK von Staley, Joanna T., Amy, Sam R., Adams, Nigel P., Chapman, Roselle E., Peyton, Jodey M., Pywell, Richard F.

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New tools for the analysis and validation of cryo‐EM maps and atomic models von Afonine, Pavel V., Klaholz, Bruno P., Moriarty, Nigel W., Poon, Billy K., Sobolev, Oleg V., Terwilliger, Thomas C., Adams, Paul D., Urzhumtsev, Alexandre

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Unified classification and risk-stratification in Acute Myeloid Leukemia von Tazi, Yanis, Arango-Ossa, Juan E., Zhou, Yangyu, Bernard, Elsa, Thomas, Ian, Gilkes, Amanda, Freeman, Sylvie, Pradat, Yoann, Johnson, Sean J., Hills, Robert, Dillon, Richard, Levine, Max F., Leongamornlert, Daniel, Butler, Adam, Ganser, Arnold, Bullinger, Lars, Döhner, Konstanze, Ottmann, Oliver, Adams, Richard, Döhner, Hartmut, Campbell, Peter J., Burnett, Alan K., Dennis, Michael, Russell, Nigel H., Devlin, Sean M., Huntly, Brian J. P., Papaemmanuil, Elli

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Circadian control of abscisic acid biosynthesis and signalling pathways revealed by genome-wide analysis of LHY binding targets von Adams, Sally, Grundy, Jack, Veflingstad, Siren R., Dyer, Nigel P., Hannah, Matthew A., Ott, Sascha, Carré, Isabelle A.

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A Global Ramachandran Score Identifies Protein Structures with Unlikely Stereochemistry von Sobolev, Oleg V., Afonine, Pavel V., Moriarty, Nigel W., Hekkelman, Maarten L., Joosten, Robbie P., Perrakis, Anastassis, Adams, Paul D.

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Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis von Kennedy, Alyssa L., Morton, Jennifer P., Manoharan, Indrani, Nelson, David M., Jamieson, Nigel B., Pawlikowski, Jeff S., McBryan, Tony, Doyle, Brendan, McKay, Colin, Oien, Karin A., Enders, Greg H., Zhang, Rugang, Sansom, Owen J., Adams, Peter D.

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Macromolecular refinement of X-ray and cryoelectron microscopy structures with Phenix/OPLS3e for improved structure and ligand quality von van Zundert, Gydo C.P., Moriarty, Nigel W., Sobolev, Oleg V., Adams, Paul D., Borrelli, Kenneth W.

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The Lancet Commission on diabetes: using data to transform diabetes care and patient lives von Chan, Juliana C N, Lim, Lee-Ling, Wareham, Nicholas J, Shaw, Jonathan E, Orchard, Trevor J, Zhang, Ping, Lau, Eric S H, Eliasson, Björn, Kong, Alice P S, Ezzati, Majid, Aguilar-Salinas, Carlos A, McGill, Margaret, Levitt, Naomi S, Ning, Guang, So, Wing-Yee, Adams, Jean, Bracco, Paula, Forouhi, Nita G, Gregory, Gabriel A, Guo, Jingchuan, Hua, Xinyang, Klatman, Emma L, Magliano, Dianna J, Ng, Boon-Peng, Ogilvie, David, Panter, Jenna, Pavkov, Meda, Shao, Hui, Unwin, Nigel, White, Martin, Wou, Constance, Ma, Ronald C W, Schmidt, Maria I, Ramachandran, Ambady, Seino, Yutaka, Bennett, Peter H, Oldenburg, Brian, Gagliardino, Juan José, Luk, Andrea O Y, Clarke, Philip M, Ogle, Graham D, Davies, Melanie J, Holman, Rury R, Gregg, Edward W

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Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases von Omar, Faisa, Findlay, Jane E., Carfray, Gemma, Allcock, Robert W., Jiang, Zhong, Moore, Caitlin, Muir, Amy L., Lannoy, Morgane, Fertig, Bracy A., Mai, Deborah, Day, Jonathan P., Bolger, Graeme, Baillie, George S., Schwiebert, Erik, Klussmann, Enno, Pyne, Nigel J., Ong, Albert C. M., Bowers, Keith, Adam, Julia M., Adams, David R., Houslay, Miles D., Henderson, David J. P.

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Pan-cancer analysis of whole genomes von Campbell, Peter J, Getz, Gad, Korbel, Jan O, Stuart, Joshua M, Jennings, Jennifer L, Stein, Lincoln D, Perry, Marc D

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PDBx/mmCIF Ecosystem: Foundational Semantic Tools for Structural Biology von Westbrook, John D., Young, Jasmine Y., Shao, Chenghua, Feng, Zukang, Guranovic, Vladimir, Lawson, Catherine L., Vallat, Brinda, Adams, Paul D., Berrisford, John M, Bricogne, Gerard, Diederichs, Kay, Joosten, Robbie P., Keller, Peter, Moriarty, Nigel W., Sobolev, Oleg V., Velankar, Sameer, Vonrhein, Clemens, Waterman, David G., Kurisu, Genji, Berman, Helen M., Burley, Stephen K., Peisach, Ezra

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A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns von Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Danyi, Alexandra, de Ridder, Jeroen, van Herpen, Carla, Lolkema, Martijn P., Steeghs, Neeltje, Getz, Gad, Morris, Quaid D., Stein, Lincoln D.

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Topographical Mapping of Isoform-Selectivity Determinants for J‑Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2 von Adams, David R, Tawati, Salha, Berretta, Giacomo, Rivas, Paula Lopez, Baiget, Jessica, Jiang, Zhong, Alsfouk, Aisha, Mackay, Simon P, Pyne, Nigel J, Pyne, Susan

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Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial von McMurray, John J.V., Holman, Rury, Alexander, Karen, Patel, Chetan, Eapen, Zubin, Gentry, Tracy, Al Kawas, Firas, Enns, Robert, Sinay, Isaac, Guerci, Bruno, Giaccari, Andrea, Pinto, Miguel, Eliasson, Bjorn, Chiang, Chern-En, Baldovino, Jorge, Besada, Diego, Dominguez, Andrea, Maldonado, Natacha, Perez Manghi, Federico, Scheen, André, Damyanova, Velichka, Kovacheva, Snezhina, Beaudry, Yves, Peterson, Sean, Rosenbloom, Alan, Krizova, Jarmila, Lastuvka, Jiri, Andersen, Ulla, Jensen, Jan Skov, Petit, Catherine, Voinot, Christel, Bott, Jochen, Donaubauer, Torsten, Erlinger, Rudolf, Grosskopf, Josef, Hagenow, Andreas, Kellerer, Monika, Neumann, Gerhard, Pohlmeier, Lars, Proepper, Felix, Kotsa, Kalliopi, Papanas, Nikolaos, Plés, Zsolt, Revesz, Katalin, Gazzaruso, Carmine, Piatti, Piermarco, Tonolo, Giancarlo, Kim, Chong-Jin, Lee, Hyoung Woo, Namgung, June, Ramirez-Diaz, Santiago-Paulino, Torres-Colores, Jose Juan, Groutars, Reginald G.E.J., Wium, Cecilie, Camacho, Luis, Garrido, Elizabeth, Gadzinski, Waldemar, Madej, Andrzej, Galstyan, Gagik, Koziolova, Natalia, Zanozina, Olga, Zykova, Tatyana, Dawood, Saleem, Makotoko, Ellen, Cuatrecasas Cambra, Guillem, Durán García, Santiago, Marazuela, Monica, Soto González, Alfonso, Olsson, Åke, Söderberg, Stefan, Chen, Jung-Fu, Hutayanon, Pisit, Aggarwala, Gaurav, Akhter, Faiq, Ashdji, Reswan, Belfort de Aguiar, Renata, Dauber, Ira, Kumar, Mariananda, Lasswell, William, Lenzmeier, Thomas, Rauzi, Frank, Shlesinger, Yshay, Tripathy, Devjit, Uwaifo, Gabriel, Vedere, Amarnath, Vo, Anthony, White, Alexander, Rosenberg, Anne, Overton, Robert, Stead, Janet, Ross, Jorge, Soffer, Joseph, Daga, Shruti, Chen, David, Taft, Lin, James, Rachel, Watson, Anthony, Schleiden, Debra, Saswadkar, Aarti, Vaphare, Ashok

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PHENIX: building new software for automated crystallographic structure determination von Adams, Paul D., Grosse-Kunstleve, Ralf W., Hung, Li-Wei, Ioerger, Thomas R., McCoy, Airlie J., Moriarty, Nigel W., Read, Randy J., Sacchettini, James C., Sauter, Nicholas K., Terwilliger, Thomas C.

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Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer von Olive, Kenneth P, Jacobetz, Michael A, Davidson, Christian J, Gopinathan, Aarthi, McIntyre, Dominick, Honess, Davina, Madhu, Basetti, Goldgraben, Mae A, Caldwell, Meredith E, Allard, David, Frese, Kristopher K, DeNicola, Gina, Feig, Christine, Combs, Chelsea, Winter, Stephen P, Ireland-Zecchini, Heather, Reichelt, Stefanie, Howat, William J, Chang, Alex, Dhara, Mousumi, Wang, Lifu, Rückert, Felix, Grützmann, Robert, Pilarsky, Christian, Izeradjene, Kamel, Hingorani, Sunil R, Huang, Pearl, Davies, Susan E, Plunkett, William, Egorin, Merrill, Hruban, Ralph H, Whitebread, Nigel, McGovern, Karen, Adams, Julian, Iacobuzio-Donahue, Christine, Griffiths, John, Tuveson, David A

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Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis von Kunkle, Brian W, Schmidt, Michael, Klein, Hans-Ulrich, Naj, Adam C, Hamilton-Nelson, Kara L, Larson, Eric B, Evans, Denis A, De Jager, Phil L, Crane, Paul K, Buxbaum, Joe D, Ertekin-Taner, Nilufer, Barnes, Lisa L, Fallin, M. Daniele, Manly, Jennifer J, Go, Rodney C. P, Obisesan, Thomas O, Kamboh, M. Ilyas, Bennett, David A, Hall, Kathleen S, Goate, Alison M, Foroud, Tatiana M, Martin, Eden R, Wang, Li-San, Byrd, Goldie S, Farrer, Lindsay A, Haines, Jonathan L, Schellenberg, Gerard D, Mayeux, Richard, Pericak-Vance, Margaret A, Reitz, Christiane, Graff-Radford, Neill R, Martinez, Izri, Ayodele, Temitope, Logue, Mark W, Cantwell, Laura B, Jean-Francois, Melissa, Kuzma, Amanda B, Adams, L.D, Vance, Jeffery M, Cuccaro, Michael L, Chung, Jaeyoon, Mez, Jesse, Lunetta, Kathryn L, Jun, Gyungah R, Lopez, Oscar L, Hendrie, Hugh C, Reiman, Eric M, Kowall, Neil W, Leverenz, James B, Small, Scott A, Levey, Allan I, Golde, Todd E, Saykin, Andrew J, Starks, Takiyah D, Albert, Marilyn S, Hyman, Bradley T, Petersen, Ronald C, Sano, Mary, Wisniewski, Thomas, Vassar, Robert, Kaye, Jeffrey A, Henderson, Victor W, DeCarli, Charles, LaFerla, Frank M, Brewer, James B, Miller, Bruce L, Swerdlow, Russell H, Van Eldik, Linda J, Paulson, Henry L, Trojanowski, John Q, Chui, Helena C, Rosenberg, Roger N, Craft, Suzanne, Grabowski, Thomas J, Asthana, Sanjay, Morris, John C, Strittmatter, Stephen M, Kukull, Walter A

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Modeling total predation to avoid perverse outcomes from cat control in a data‐poor island ecosystem von Plein, Michaela, O'Brien, Katherine R., Holden, Matthew H., Adams, Matthew P., Baker, Christopher M., Bean, Nigel G., Sisson, Scott A., Bode, Michael, Mengersen, Kerrie L., McDonald‐Madden, Eve

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A new default restraint library for the protein backbone in Phenix: a conformation-dependent geometry goes mainstream von Moriarty, Nigel W., Tronrud, Dale E., Adams, Paul D., Karplus, P. Andrew

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Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study von Jabbari, Edwin, Koga, Shunsuke, Valentino, Rebecca R, Reynolds, Regina H, Ferrari, Raffaele, Tan, Manuela M X, Rowe, James B, Dalgard, Clifton L, Scholz, Sonja W, Dickson, Dennis W, Warner, Thomas T, Revesz, Tamas, Höglinger, Günter U, Ross, Owen A, Ryten, Mina, Hardy, John, Shoai, Maryam, Morris, Huw R, Mok, Kin Y., Murphy, David P., Al-Sarraj, Safa, Troakes, Claire, Gentleman, Steve M., Allinson, Kieren S.J., Jaunmuktane, Zane, Holton, Janice L., Lees, Andrew J., Morris, Christopher M., Compta, Yaroslau, Gelpi, Ellen, van Swieten, John C., Rajput, Alex, Ferguson, Leslie, Cookson, Mark R., Gibbs, J. Raphael, Blauwendraat, Cornelis, Ding, Jinhui, Chia, Ruth, Traynor, Bryan J., Pantelyat, Alexander, Viollet, Coralie, Pletnikova, Olga, Troncoso, Juan C., Rosenthal, Liana S., Boxer, Adam L., Respondek, Gesine, Arzberger, Thomas, Roeber, Sigrun, Giese, Armin, Burn, David J., Pavese, Nicola, Gerhard, Alexander, Kobylecki, Christopher, Leigh, P. Nigel, Church, Alistair, T.M. Hu, Michele

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