Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme von Kaczmarski, Joe A., Mahawaththa, Mithun C., Feintuch, Akiva, Clifton, Ben E., Adams, Luke A., Goldfarb, Daniella, Otting, Gottfried, Jackson, Colin J.

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Enhanced Cytotoxicity through Conjugation of a “Clickable” Luminescent Re(I) Complex to a Cell-Penetrating Lipopeptide von Leonidova, Anna, Pierroz, Vanessa, Adams, Luke A, Barlow, Nicholas, Ferrari, Stefano, Graham, Bim, Gasser, Gilles

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Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA von Adams, Luke A., Sharma, Pooja, Mohanty, Biswaranjan, Ilyichova, Olga V., Mulcair, Mark D., Williams, Martin L., Gleeson, Ellen C., Totsika, Makrina, Doak, Bradley C., Caria, Sofia, Rimmer, Kieran, Horne, James, Shouldice, Stephen R., Vazirani, Mansha, Headey, Stephen J., Plumb, Brent R., Martin, Jennifer L., Heras, Begoña, Simpson, Jamie S., Scanlon, Martin J.

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Pulse EPR-enabled interpretation of scarce pseudocontact shifts induced by lanthanide binding tags von Abdelkader, Elwy H., Yao, Xuejun, Feintuch, Akiva, Adams, Luke A., Aurelio, Luigi, Graham, Bim, Goldfarb, Daniella, Otting, Gottfried

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Site-Specific Incorporation of Selenocysteine by Genetic Encoding as a Photocaged Unnatural Amino Acid von Welegedara, Adarshi P, Adams, Luke A, Huber, Thomas, Graham, Bim, Otting, Gottfried

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Genetic Encoding of N 6‑(((Trimethylsilyl)­methoxy)­carbonyl)‑l‑lysine for NMR Studies of Protein–Protein and Protein–Ligand Interactions von Abdelkader, Elwy H, Qianzhu, Haocheng, Tan, Yi Jiun, Adams, Luke A, Huber, Thomas, Otting, Gottfried

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Selective Distance Measurements Using Triple Spin Labeling with Gd3+, Mn2+, and a Nitroxide von Wu, Zuyan, Feintuch, Akiva, Collauto, Alberto, Adams, Luke A., Aurelio, Luigi, Graham, Bim, Otting, Gottfried, Goldfarb, Daniella

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Genetically encoded amino acids with tert-butyl and trimethylsilyl groups for site-selective studies of proteins by NMR spectroscopy von Loh, Choy Theng, Adams, Luke A., Graham, Bim, Otting, Gottfried

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Chemical Tagging with tert‐Butyl and Trimethylsilyl Groups for Measuring Intermolecular Nuclear Overhauser Effects in a Large Protein–Ligand Complex von Jabar, Shereen, Adams, Luke A., Wang, Yao, Aurelio, Luigi, Graham, Bim, Otting, Gottfried

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Rapid Elaboration of Fragments into Leads Applied to Bromodomain‑3 Extra-Terminal Domain von Adams, Luke A., Wilkinson-White, Lorna E., Gunzburg, Menachem J., Headey, Stephen J., Mohanty, Biswaranjan, Scanlon, Martin J., Capuano, Ben, Mackay, Joel P., Doak, Bradley C.

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Diastereoselective Synthesis of Cyclopropane Amino Acids Using Diazo Compounds Generated in Situ von Adams, Luke A, Aggarwal, Varinder K, Bonnert, Roger V, Bressel, Bettina, Cox, Russell J, Shepherd, Jon, de Vicente, Javier, Walter, Magnus, Whittingham, William G, Winn, Caroline L

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Small neutral Gd(iii) tags for distance measurements in proteins by double electron-electron resonance experiments von Mahawaththa, Mithun C, Lee, Michael D, Giannoulis, Angeliki, Adams, Luke A, Feintuch, Akiva, Swarbrick, James D, Graham, Bim, Nitsche, Christoph, Goldfarb, Daniella, Otting, Gottfried

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Trimethylsilyl tag for probing protein–ligand interactions by NMR von Becker, Walter, Adams, Luke A., Graham, Bim, Wagner, Gabriel E., Zangger, Klaus, Otting, Gottfried, Nitsche, Christoph

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Selective Distance Measurements Using Triple Spin Labeling with Gd 3+ , Mn 2+ , and a Nitroxide von Wu, Zuyan, Feintuch, Akiva, Collauto, Alberto, Adams, Luke A, Aurelio, Luigi, Graham, Bim, Otting, Gottfried, Goldfarb, Daniella

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Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors von Baker, Jillian G, Adams, Luke A, Salchow, Karolina, Mistry, Shailesh N, Middleton, Richard J, Hill, Stephen J, Kellam, Barrie

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A concise synthesis of d, l-brevianamide B via a biomimetically-inspired IMDA construction von Adams, Luke A., Valente, Meriah W.N., Williams, Robert M.

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Concise synthesis of the core bicyclo[2.2.2]diazaoctane ring common to asperparaline, paraherquamide, and stephacidin alkaloids von Adams, Luke A., Gray, Chandele R., Williams, Robert M.

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A new synthesis of phosphoramidates: inhibitors of the key bacterial enzyme aspartate semi-aldehyde dehydrogenase von Adams, Luke A, Cox, Russell J, Gibson, Jennifer S, Mayo-Martín, M Belén, Walter, Magnus, Whittingham, William

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Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA von Adams, Luke A., Sharma, Pooja, Mohanty, Biswaranjan, Ilyichova, Olga V., Mulcair, Mark D., Williams, Martin L., Gleeson, Ellen C., Totsika, Makrina, Doak, Bradley C., Caria, Sofia, Rimmer, Kieran, Horne, James, Shouldice, Stephen R., Vazirani, Mansha, Headey, Stephen J., Plumb, Brent R., Martin, Jennifer L., Heras, Begoña, Simpson, Jamie S., Scanlon, Martin J.

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Efficient synthesis of protected cyclopropyl beta-aspartylphosphates von Adams, Luke A, Charmant, Jonathan P H, Cox, Russell J, Walter, Magnus, Whittingham, William G

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