In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma von Karreth, Florian A., Tay, Yvonne, Perna, Daniele, Ala, Ugo, Tan, Shen Mynn, Rust, Alistair G., DeNicola, Gina, Webster, Kaitlyn A., Weiss, Dror, Perez-Mancera, Pedro A., Krauthammer, Michael, Halaban, Ruth, Provero, Paolo, Adams, David J., Tuveson, David A., Pandolfi, Pier Paolo

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Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain von Clark, Richard J, Jensen, Jonas, Nevin, Simon T, Callaghan, Brid P, Adams, David J, Craik, David J

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The Valley of Death in anticancer drug development: a reassessment von Adams, David J

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Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing von Bach, Karsten, Pensa, Sara, Grzelak, Marta, Hadfield, James, Adams, David J., Marioni, John C., Khaled, Walid T.

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No unexpected CRISPR-Cas9 off-target activity revealed by trio sequencing of gene-edited mice von Iyer, Vivek, Boroviak, Katharina, Thomas, Mark, Doe, Brendan, Riva, Laura, Ryder, Edward, Adams, David J

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The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo von Karreth, Florian A., Reschke, Markus, Ruocco, Anna, Ng, Christopher, Chapuy, Bjoern, Léopold, Valentine, Sjoberg, Marcela, Keane, Thomas M., Verma, Akanksha, Ala, Ugo, Tay, Yvonne, Wu, David, Seitzer, Nina, Velasco-Herrera, Martin Del Castillo, Bothmer, Anne, Fung, Jacqueline, Langellotto, Fernanda, Rodig, Scott J., Elemento, Olivier, Shipp, Margaret A., Adams, David J., Chiarle, Roberto, Pandolfi, Pier Paolo

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Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilities von Rabbie, Roy, Ferguson, Peter, Molina‐Aguilar, Christian, Adams, David J, Robles‐Espinoza, Carla D

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Nicotinic acetylcholine receptor subtype expression, function, and pharmacology: Therapeutic potential of α-conotoxins von Tae, Han-Shen, Adams, David J.

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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis von Jackstadt, Rene, van Hooff, Sander R., Leach, Joshua D., Cortes-Lavaud, Xabier, Lohuis, Jeroen O., Ridgway, Rachel A., Wouters, Valérie M., Roper, Jatin, Kendall, Timothy J., Roxburgh, Campbell S., Horgan, Paul G., Nixon, Colin, Nourse, Craig, Gunzer, Matthias, Clark, William, Hedley, Ann, Yilmaz, Omer H., Rashid, Mamunur, Bailey, Peter, Biankin, Andrew V., Campbell, Andrew D., Adams, David J., Barry, Simon T., Steele, Colin W., Medema, Jan Paul, Sansom, Owen J.

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Placentation defects are highly prevalent in embryonic lethal mouse mutants von Perez-Garcia, Vicente, Fineberg, Elena, Wilson, Robert, Murray, Alexander, Mazzeo, Cecilia Icoresi, Tudor, Catherine, Sienerth, Arnold, White, Jacqueline K., Tuck, Elizabeth, Ryder, Edward J., Gleeson, Diane, Siragher, Emma, Wardle-Jones, Hannah, Staudt, Nicole, Wali, Neha, Collins, John, Geyer, Stefan, Busch-Nentwich, Elisabeth M., Galli, Antonella, Smith, James C., Robertson, Elizabeth, Adams, David J., Weninger, Wolfgang J., Mohun, Timothy, Hemberger, Myriam

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Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals von Stefflova, Klara, Thybert, David, Wilson, Michael D., Streeter, Ian, Aleksic, Jelena, Karagianni, Panagiota, Brazma, Alvis, Adams, David J., Talianidis, Iannis, Marioni, John C., Flicek, Paul, Odom, Duncan T.

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RetroSeq: transposable element discovery from next-generation sequencing data von Keane, Thomas M, Wong, Kim, Adams, David J

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Collateral damage and CRISPR genome editing von Thomas, Mark, Burgio, Gaetan, Adams, David J, Iyer, Vivek

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Fungal cell wall chitinases and glucanases von Adams, David J

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The mutational signature profile of known and suspected human carcinogens in mice von Riva, Laura, Pandiri, Arun R., Li, Yun Rose, Droop, Alastair, Hewinson, James, Quail, Michael A., Iyer, Vivek, Shepherd, Rebecca, Herbert, Ronald A., Campbell, Peter J., Sills, Robert C., Alexandrov, Ludmil B., Balmain, Allan, Adams, David J.

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Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis von Espana-Agusti, Judit, Warren, Anne, Chew, Su Kit, Adams, David J., Matakidou, Athena

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The role of ion channels in T cell function and disease von Manolios, Nicholas, Papaemmanouil, John, Adams, David J.

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Advances in Xanthan Gum-Based Systems for the Delivery of Therapeutic Agents von Jadav, Mahima, Pooja, Deep, Adams, David J, Kulhari, Hitesh

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The mutational landscapes of genetic and chemical models of Kras-driven lung cancer von Westcott, Peter M. K., Halliwill, Kyle D., To, Minh D., Rashid, Mamunur, Rust, Alistair G., Keane, Thomas M., Delrosario, Reyno, Jen, Kuang-Yu, Gurley, Kay E., Kemp, Christopher J., Fredlund, Erik, Quigley, David A., Adams, David J., Balmain, Allan

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ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks von Balmus, Gabriel, Pilger, Domenic, Coates, Julia, Demir, Mukerrem, Sczaniecka-Clift, Matylda, Barros, Ana C., Woods, Michael, Fu, Beiyuan, Yang, Fengtang, Chen, Elisabeth, Ostermaier, Matthias, Stankovic, Tatjana, Ponstingl, Hannes, Herzog, Mareike, Yusa, Kosuke, Martinez, Francisco Munoz, Durant, Stephen T., Galanty, Yaron, Beli, Petra, Adams, David J., Bradley, Allan, Metzakopian, Emmanouil, Forment, Josep V., Jackson, Stephen P.

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