Programmable Syringe Pump for Selective Micro Droplet Deposition von Kurniawan, Erry Dwi, Adam, Alwin, Salik, Muhammad Ichlasul, Gareso, Paulus Lobo

Volltext

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia von Tron, Adriana E., Belmonte, Matthew A., Adam, Ammar, Aquila, Brian M., Boise, Lawrence H., Chiarparin, Elisabetta, Cidado, Justin, Embrey, Kevin J., Gangl, Eric, Gibbons, Francis D., Gregory, Gareth P., Hargreaves, David, Hendricks, J. Adam, Johannes, Jeffrey W., Johnstone, Ricky W., Kazmirski, Steven L., Kettle, Jason G., Lamb, Michelle L., Matulis, Shannon M., Nooka, Ajay K., Packer, Martin J., Peng, Bo, Rawlins, Philip B., Robbins, Daniel W., Schuller, Alwin G., Su, Nancy, Yang, Wenzhan, Ye, Qing, Zheng, Xiaolan, Secrist, J. Paul, Clark, Edwin A., Wilson, David M., Fawell, Stephen E., Hird, Alexander W.

Volltext

Impact of Diabetes Mellitus on Early Clinical Outcome and Stent Restenosis after Carotid Artery Stenting von Achim, Alexandru, Lackó, Dávid, Hüttl, Artúr, Csobay-Novák, Csaba, Csavajda, Ádám, Sótonyi, Péter, Merkely, Béla, Nemes, Balázs, Ruzsa, Zoltán

Volltext

The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models von Schuller, Alwin G, Barry, Evan R, Jones, Rhys D O, Henry, Ryan E, Frigault, Melanie M, Beran, Garry, Linsenmayer, David, Hattersley, Maureen, Smith, Aaron, Wilson, Joanne, Cairo, Stefano, Déas, Olivier, Nicolle, Delphine, Adam, Ammar, Zinda, Michael, Reimer, Corinne, Fawell, Stephen E, Clark, Edwin A, D'Cruz, Celina M

Volltext

AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-xL, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia von Balachander, Srividya B., Criscione, Steven W., Byth, Kate F., Cidado, Justin, Adam, Ammar, Lewis, Paula, Macintyre, Terry, Wen, Shenghua, Lawson, Deborah, Burke, Kathleen, Lubinski, Tristan, Tyner, Jeffrey W., Kurtz, Stephen E., McWeeney, Shannon K., Varnes, Jeffrey, Diebold, R. Bruce, Gero, Thomas, Ioannidis, Stephanos, Hennessy, Edward J., McCoull, William, Saeh, Jamal C., Tabatabai, Areya, Tavana, Omid, Su, Nancy, Schuller, Alwin, Garnett, Mathew J., Jaaks, Patricia, Coker, Elizabeth A., Gregory, Gareth P., Newbold, Andrea, Johnstone, Ricky W., Gangl, Eric, Wild, Martin, Zinda, Michael, Secrist, J. Paul, Davies, Barry R., Fawell, Stephen E., Gibbons, Francis D.

Volltext

Biomarker-driven strategy for MCL1 inhibition in T-cell lymphomas von Koch, Raphael, Christie, Amanda L., Crombie, Jennifer L., Palmer, Adam C., Plana, Deborah, Shigemori, Kay, Morrow, Sara N., Van Scoyk, Alexandria, Wu, Wenchao, Brem, Elizabeth A., Secrist, J. Paul, Drew, Lisa, Schuller, Alwin G., Cidado, Justin, Letai, Anthony, Weinstock, David M.

Volltext

Cancer-of-Unknown-Primary-Origin: A SEER–Medicare Study of Patterns of Care and Outcomes among Elderly Patients in Clinical Practice von Mileshkin, Linda, Bochtler, Tilmann, Gatta, Gemma, Kurzrock, Razelle, Beringer, Andreas, Müller-Ohldach, Mathis, Surinach, Andy, Perret, Camille, Thomas, Marlene, Gondos, Adam, Krämer, Alwin

Volltext

Design and optimisation of dendrimer-conjugated Bcl-2/xL inhibitor, AZD0466, with improved therapeutic index for cancer therapy von Patterson, Claire M., Balachander, Srividya B., Grant, Iain, Pop-Damkov, Petar, Kelly, Brian, McCoull, William, Parker, Jeremy, Giannis, Michael, Hill, Kathryn J., Gibbons, Francis D., Hennessy, Edward J., Kemmitt, Paul, Harmer, Alexander R., Gales, Sonya, Purbrick, Stuart, Redmond, Sean, Skinner, Matthew, Graham, Lorraine, Secrist, J. Paul, Schuller, Alwin G., Wen, Shenghua, Adam, Ammar, Reimer, Corinne, Cidado, Justin, Wild, Martin, Gangl, Eric, Fawell, Stephen E., Saeh, Jamal, Davies, Barry R., Owen, David J., Ashford, Marianne B.

Volltext

Moulded cast compared with K-wire fixation after manipulation of an acute dorsally displaced distal radius fracture: the DRAFFT 2 RCT von Costa, Matthew L, Achten, Juul, Ooms, Alexander, Png, May Ee, Cook, Jonathan, Dritsaki, Melina, Lamb, Sarah E, Lerner, Robin, Draper, Kylea, Campolier, Marta, Dakin, Helen, McGibbon, Alwin, Parsons, Nicholas, Hedley, Helen, Dias, Joseph

Volltext

In-vivo multilaboratory investigation of the optical properties of the human head von Farina, Andrea, Torricelli, Alessandro, Bargigia, Ilaria, Spinelli, Lorenzo, Cubeddu, Rinaldo, Foschum, Florian, Jäger, Marion, Simon, Emanuel, Fugger, Oliver, Kienle, Alwin, Martelli, Fabrizio, Di Ninni, Paola, Zaccanti, Giovanni, Milej, Daniel, Sawosz, Piotr, Kacprzak, Michał, Liebert, Adam, Pifferi, Antonio

Volltext

Acquired savolitinib resistance in non-small cell lung cancer arises via multiple mechanisms that converge on MET-independent mTOR and MYC activation von Henry, Ryan E, Barry, Evan R, Castriotta, Lillian, Ladd, Brendon, Markovets, Aleksandra, Beran, Garry, Ren, Yongxin, Zhou, Feng, Adam, Ammar, Zinda, Michael, Reimer, Corinne, Qing, Weiguo, Su, Weiguo, Clark, Edwin, D'Cruz, Celina M, Schuller, Alwin G

Volltext

Clinically Translatable Formulation Strategies for Systemic Administration of Nerve‐Specific Probes von Barth, Connor W., Shah, Vidhi M., Wang, Lei G., Antaris, Alexander L., Klaassen, Alwin, Sorger, Jonathan, Rao, Deepa A., Kerr, Darcy A., Henderson, Eric R., Alani, Adam W. G., Gibbs, Summer L.

Volltext

A Dual Bcl-2/xL Inhibitor Induces Tumor Cell Apoptosis in a Hematopoietic Xenograft Model von Adam, Ammar, Byth, Kate, Secrist, Paul, Schuller, Alwin, Reimer, Corinne, Lawson, Deborah, MacIntyre, Terry, Powell, Francoise

Volltext

Virology under the Microscope-a Call for Rational Discourse von Goodrum, Felicia, Lowen, Anice C, Lakdawala, Seema, Alwine, James, Casadevall, Arturo, Imperiale, Michael J, Atwood, Walter, Avgousti, Daphne, Baines, Joel, Banfield, Bruce, Banks, Lawrence, Bhaduri-McIntosh, Sumita, Bhattacharya, Deepta, Blanco-Melo, Daniel, Bloom, David, Boon, Adrianus, Boulant, Steeve, Brandt, Curtis, Broadbent, Andrew, Brooke, Christopher, Cameron, Craig, Campos, Samuel, Caposio, Patrizia, Chan, Gary, Cliffe, Anna, Coffin, John, Collins, Kathleen, Damania, Blossom, Daugherty, Matthew, Debbink, Kari, DeCaprio, James, Dermody, Terence, Dikeakos, Jimmy, DiMaio, Daniel, Dinglasan, Rhoel, Duprex, W Paul, Dutch, Rebecca, Elde, Nels, Emerman, Michael, Enquist, Lynn, Fane, Bentley, Fernandez-Sesma, Ana, Flenniken, Michelle, Frappier, Lori, Frieman, Matthew, Frueh, Klaus, Gack, Michaela, Gaglia, Marta, Gallagher, Tom, Galloway, Denise, García-Sastre, Adolfo, Geballe, Adam, Glaunsinger, Britt, Goff, Stephen, Greninger, Alexander, Hancock, Meaghan, Harris, Eva, Heaton, Nicholas, Heise, Mark, Heldwein, Ekaterina, Hogue, Brenda, Horner, Stacy, Hutchinson, Edward, Hyser, Joseph, Jackson, William, Kalejta, Robert, Kamil, Jeremy, Karst, Stephanie, Kirchhoff, Frank, Knipe, David, Kowalik, Timothy, Lagunoff, Michael, Laimins, Laimonis, Langlois, Ryan, Lauring, Adam, Lee, Benhur, Leib, David, Liu, Shan-Lu, Longnecker, Richard, Lopez, Carolina, Luftig, Micah, Lund, Jennifer, Manicassamy, Balaji, McFadden, Grant, McIntosh, Michael, Mehle, Andrew, Miller, W Allen, Mohr, Ian, Moody, Cary, Moorman, Nathaniel, Moscona, Anne, Mounce, Bryan, Munger, Joshua, Münger, Karl, Murphy, Eain, Naghavi, Mojgan, Nelson, Jay, Neufeldt, Christopher, Nikolich, Janko, O'Connor, Christine

Volltext

The effect of consumption of natural non-dairy probiotics on human health von Sikora, Dominika, Wojciechowska-Alwin, Natalia, Lipski, Adam, Bogdański, Paweł, Skrypnik, Damian

Volltext

Abstract 1477: Pharmacodynamic response and anti-tumor activity of the MET inhibitor AZD6094 in papillary renal cell carcinoma patient derived xenograft models von Schuller, Alwin, Barry, Evan, Jones, Rhys, Frigault, Melanie, Beran, Garry, Henry, Ryan, Linsenmayer, David, Hattersley, Maureen, Smith, Aaron, Wilson, Joanne, Adam, Ammar, Zinda, Michael, Reimer, Corinne, Fawell, Stephen, Clark, Edwin, D'Cruz, Celina

Volltext

Abstract LB-C22: Acquired resistance to the cMET inhibitor savolitinib in lung cancer models through EGFR/mTOR/MYC deregulation and adoption of PIM signaling von Henry, Ryan E., Barry, Evan R., Ladd, Brendon, Markovets, Aleksandra, Beran, Garry J., Ren, Yongxin, Zhou, Feng, Castriotta, Lillian, Adam, Ammar, Qing, Weiguo, Su, Weiguo, Clark, Edwin, D'Cruz, Celina M., Schuller, Alwin

Volltext

Single-Mode to Multi-Mode Crossover in Thin-Load Polymethyl Methacrylate Plasmonic Waveguides von Großmann, Malte, Thomaschewski, Martin, Klick, Alwin, Goszczak, Arkadiusz Jarosław, Sobolewska, Elżbieta Karolina, Leißner, Till, Adam, Jost, Fiutowski, Jacek, Rubahn, Horst-Günter, Bauer, Michael

Volltext

Design and optimisation of dendrimer-conjugated Bcl-2/x L inhibitor, AZD0466, with improved therapeutic index for cancer therapy von Patterson, Claire M, Balachander, Srividya B, Grant, Iain, Pop-Damkov, Petar, Kelly, Brian, McCoull, William, Parker, Jeremy, Giannis, Michael, Hill, Kathryn J, Gibbons, Francis D, Hennessy, Edward J, Kemmitt, Paul, Harmer, Alexander R, Gales, Sonya, Purbrick, Stuart, Redmond, Sean, Skinner, Matthew, Graham, Lorraine, Secrist, J Paul, Schuller, Alwin G, Wen, Shenghua, Adam, Ammar, Reimer, Corinne, Cidado, Justin, Wild, Martin, Gangl, Eric, Fawell, Stephen E, Saeh, Jamal, Davies, Barry R, Owen, David J, Ashford, Marianne B

Volltext

AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-x L , Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia von Balachander, Srividya B, Criscione, Steven W, Byth, Kate F, Cidado, Justin, Adam, Ammar, Lewis, Paula, Macintyre, Terry, Wen, Shenghua, Lawson, Deborah, Burke, Kathleen, Lubinski, Tristan, Tyner, Jeffrey W, Kurtz, Stephen E, McWeeney, Shannon K, Varnes, Jeffrey, Diebold, R Bruce, Gero, Thomas, Ioannidis, Stephanos, Hennessy, Edward J, McCoull, William, Saeh, Jamal C, Tabatabai, Areya, Tavana, Omid, Su, Nancy, Schuller, Alwin, Garnett, Mathew J, Jaaks, Patricia, Coker, Elizabeth A, Gregory, Gareth P, Newbold, Andrea, Johnstone, Ricky W, Gangl, Eric, Wild, Martin, Zinda, Michael, Secrist, J Paul, Davies, Barry R, Fawell, Stephen E, Gibbons, Francis D

Volltext