An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism von Ptacin, Jerod L., Caffaro, Carolina E., Ma, Lina, San Jose Gall, Kristine M., Aerni, Hans R., Acuff, Nicole V., Herman, Rob W., Pavlova, Yelena, Pena, Michael J., Chen, David B., Koriazova, Lilia K., Shawver, Laura K., Joseph, Ingrid B., Milla, Marcos E.

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Tumor progression locus 2 differentially regulates IFNγ and IL-17 production by effector CD4+ T cells in a T cell transfer model of colitis von Acuff, Nicole V, Li, Xin, Kirkland, Rebecca, Nagy, Tamas, Watford, Wendy T

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Using Visualization of t -Distributed Stochastic Neighbor Embedding To Identify Immune Cell Subsets in Mouse Tumors von Acuff, Nicole V, Linden, Joel

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A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism von Ptacin, Jerod L., Ma, Lina, Caffaro, Carolina E., Acuff, Nicole V., Germar, Kristine, Severy, Peter, Qu, Yanyan, Vela, Jose-Luis, Cai, Xinming, San Jose, Kristine M., Aerni, Hans R., Chen, David B., Esche, Ean, Ismaili, Taylor K., Herman, Rob, Pavlova, Yelena, Pena, Michael J., Nguyen, Jasmine, Koriazova, Lilia K., Shawver, Laura K., Joseph, Ingrid B., Mooney, Jill, Peakman, Mark, Milla, Marcos E.

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Tpl2 Promotes Innate Cell Recruitment and Effector T Cell Differentiation To Limit Citrobacter rodentium Burden and Dissemination von Acuff, Nicole V, Li, Xin, Latha, Krishna, Nagy, Tamas, Watford, Wendy T

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Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing von Acuff, Nicole V., Li, Xin, Elmore, Jessica, Rada, Balázs, Watford, Wendy T.

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Severe Dermatitis Associated with Spontaneous Staphylococcus xylosus Infection in Rag-/-Tpl2-/- Mice von Acuff, Nicole V, LaGatta, Monica, Nagy, Tamas, Watford, Wendy T

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Tumor Progression Locus 2 (Tpl2) Activates the Mammalian Target of Rapamycin (mTOR) Pathway, Inhibits Forkhead Box P3 (FoxP3) Expression, and Limits Regulatory T Cell (Treg) Immuno... von Li, Xin, Acuff, Nicole V., Peeks, Angela R., Kirkland, Rebecca, Wyatt, Kara D., Nagy, Tamas, Watford, Wendy T.

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A Precision Engineered Interleukin-2 for Bolstering CD8+ T- and NK-cell Activity without Eosinophilia and Vascular Leak Syndrome in Nonhuman Primates von Ma, Lina, Acuff, Nicole V, Joseph, Ingrid B, Ptacin, Jerod L, Caffaro, Carolina E, San Jose, Kristine M, Aerni, Hans R, Carrio, Roberto, Byers, Anthony M, Herman, Rob W, Pavlova, Yelena, Pena, Michael J, Chen, David B, Buetz, Christen, Ismaili, Taylor K, Pham, Helene V, Cucchetti, Margot, Sassoon, Ingrid, Koriazova, Lilia K, Leveque, Joseph A, Shawver, Laura K, Mooney, Jill M, Milla, Marcos E

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Novel monoclonal antibodies for the detection of human TLR9 von Acuff, Nicole V, Oida, Takatoku, Divekar, Anagha A, Yang, Xifeng

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Peripheral blood CD115 (CSF-1R) expression is anticoagulant- and time-dependent von Acuff, Nicole V, Divekar, Anagha A, Yang, Xifeng

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The MAP kinase, tumor progression locus 2 (Tpl2), activates the Akt/mTOR/S6 ribosomal protein pathway, inhibits Foxp3 expression and limits Treg immunosuppressive functions von Li, Xin, Acuff, Nicole V, Peeks, Angela, Kirkland, Rebecca, Nagy, Tamas, Watford, Wendy Tharpe

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Tumor Progression Locus 2 Differentially Regulates IFN[gamma] and IL-17 Production by Effector CD4.sup.+ T Cells in a T Cell Transfer Model of Colitis von Acuff, Nicole V, Li, Xin, Kirkland, Rebecca, Nagy, Tamas, Watford, Wendy T

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Tumor Progression Locus 2 Differentially Regulates IFN gamma and IL-17 Production by Effector CD4+ T Cells in a T Cell Transfer Model of Colitis: e0119885 von Acuff, Nicole V, Li, Xin, Kirkland, Rebecca, Nagy, Tamas, Watford, Wendy T

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Anti-TLR9 agents and compositions and methods for making and using the same von ACUFF NICOLE V, DIVEKAR ANAGHA A, OIDA TAKATOKU

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