The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming von Eng, C H, Abraham, R T

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Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening von Strohecker, A M, Joshi, S, Possemato, R, Abraham, R T, Sabatini, D M, White, E

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Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism von Gingras, A C, Gygi, S P, Raught, B, Polakiewicz, R D, Abraham, R T, Hoekstra, M F, Aebersold, R, Sonenberg, N

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A role for ATR in the DNA damage-induced phosphorylation of p53 von Tibbetts, R S, Brumbaugh, K M, Williams, J M, Sarkaria, J N, Cliby, W A, Shieh, S Y, Taya, Y, Prives, C, Abraham, R T

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002 von Brunn, G. J., Williams, J., Sabers, C., Wiederrecht, G., Lawrence, J. C., Abraham, R. T.

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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine von SARKARIA, J. N, BUSBY, E. C, TIBBETTS, R. S, ROOS, P, TAYA, Y, KARNITZ, L. M, ABRAHAM, R. T

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A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells von SEKULIC, A, HUDSON, C. C, HOMME, J. L, PENG YIN, OTTERNESS, D. M, KARNITZ, L. M, ABRAHAM, R. T

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The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1 von BUSBY, E. C, LEISTRITZ, D. F, ABRAHAM, R. T, KARNITZ, L. M, SARKARIA, J. N

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Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent Wortmannin von SARKARIA, J. N, TIBBETTS, R. S, BUSBY, E. C, KENNEDY, A. P, HILL, D. E, ABRAHAM, R. T

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Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin von Brunn, Gregory J., Hudson, Christine C., Sekulić, Aleksandar, Williams, Josie M., Hosoi, Hajime, Houghton, Peter J., Lawrence, John C., Abraham, Robert T.

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Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells von HOSOI, H, DILLING, M. B, SHIKATA, T, LIU, L. N, SHU, L, ASHMUN, R. A, GERMAIN, G. S, ABRAHAM, R. T, HOUGHTON, P. J

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PI 3-kinase related kinases: ‘big’ players in stress-induced signaling pathways von Abraham, Robert T.

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Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events von SECRIST, J. P, BURNS, L. A, KARNITZ, L, KORETZKY, G. A, ABRAHAM, R. T

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Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway von Karnitz, Larry M., Burns, Leigh Ann, Sutor, Shari L., Blenis, John, Abraham, Robert T.

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Rapamycin inhibition of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes von Morice, W.G., Wiederrecht, G, Brunn, G.J., Siekierka, J.J., Abraham, R.T.

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Cell cycle checkpoint signaling through the ATM and ATR kinases von Abraham, R T

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Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases von Abraham, RT, Acquarone, M, Andersen, A, Asensi, A, Bellé, R, Berger, F, Bergounioux, C, Brunn, G, Buquet-Fagot, C, Fagot, D, Glab, N, Goudeau, H, Goudeau, M, Guerrier, P, Houghton, P, Hendriks, H, Kloareg, B, Lippai, M, Marie, D, Maro, B, Meijer, L, Mester, J, Mulner-Lorillon, O, Poulet, SA, Schierenberg, E, Schutte, B, Vaulot, D, Verlhac, MH

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress von Tibbetts, R S, Cortez, D, Brumbaugh, K M, Scully, R, Livingston, D, Elledge, S J, Abraham, R T

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The mRNA Surveillance Protein hSMG-1 Functions in Genotoxic Stress Response Pathways in Mammalian Cells von Brumbaugh, Kathryn M., Otterness, Diane M., Geisen, Christoph, Oliveira, Vasco, Brognard, John, Li, Xiaojie, Lejeune, Fabrice, Tibbetts, Randal S., Maquat, Lynne E., Abraham, Robert T.

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Distinct requirements for Ras oncogenesis in human versus mouse cells von Hamad, Nesrin M, Elconin, Joel H, Karnoub, Antoine E, Bai, Wenli, Rich, Jeremy N, Abraham, Robert T, Der, Channing J, Counter, Christopher M

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