Direct CDKN2 Modulation of CDK4 Alters Target Engagement of CDK4 Inhibitor Drugs von Green, Jennifer L, Okerberg, Eric S, Sejd, Josilyn, Palafox, Marta, Monserrat, Laia, Alemayehu, Senait, Wu, Jiangyue, Sykes, Maria, Aban, Arwin, Serra, Violeta, Nomanbhoy, Tyzoon

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Functional Interrogation of the Kinome Using Nucleotide Acyl Phosphates von Patricelli, Matthew P, Szardenings, A. Katrin, Liyanage, Marek, Nomanbhoy, Tyzoon K, Wu, Min, Weissig, Helge, Aban, Arwin, Chun, Doris, Tanner, Stephen, Kozarich, John W

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Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics von Okerberg, Eric S, Hainley, Anna, Brown, Heidi, Aban, Arwin, Alemayehu, Senait, Shih, Ann, Wu, Jane, Patricelli, Matthew P, Kozarich, John W, Nomanbhoy, Tyzoon, Rosenblum, Jonathan S

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Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics von Okerberg, Eric S, Hainley, Anna, Brown, Heidi, Aban, Arwin, Alemayehu, Senait, Shih, Ann, Wu, Jane, Patricelli, Matthew P, Kozarich, John W, Nomanbhoy, Tyzoon, Rosenblum, Jonathan S

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In Situ Kinase Profiling Reveals Functionally Relevant Properties of Native Kinases von Patricelli, Matthew P., Nomanbhoy, Tyzoon K., Wu, Jiangyue, Brown, Heidi, Zhou, David, Zhang, Jianming, Jagannathan, Subadhra, Aban, Arwin, Okerberg, Eric, Herring, Chris, Nordin, Brian, Weissig, Helge, Yang, Qingkai, Lee, Jiing-Dwan, Gray, Nathanael S., Kozarich, John W.

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Abstract 5167: Profiling GTPases in native proteomes with a GTP acyl phosphate probe von Nomanbhoy, Tyzoon K., Shih, Ann, Aban, Arwin

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Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response von Nomanbhoy, Tyzoon K, Sharma, Geeta, Brown, Heidi, Wu, Jiangyue, Aban, Arwin, Vogeti, Subha, Alemayehu, Senait, Sykes, Maria, Rosenblum, Jonathan S, Kozarich, John W

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Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase‑6 von Okerberg, Eric S, Dagbay, Kevin B, Green, Jennifer L, Soni, Ishankumar, Aban, Arwin, Nomanbhoy, Tyzoon K, Savinov, Sergey N, Hardy, Jeanne A, Kozarich, John W

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Abstract 3092: In-situ Kinome wide profiling of Palbociclib treated COLO-205 human tumor xenograft samples von Sharma, Geeta, Vogeti, Subha, Grant, Wendy, Wu, Shuzhen, Dias, Christa, Nomanbhoy, Tyzoon, Wu, Jiangyue, Aban, Arwin

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Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1[alpha] by Chemical Proteomics von Okerberg, Eric S, Hainley, Anna, Brown, Heidi, Aban, Arwin, Alemayehu, Senait, Shih, Ann, Wu, Jane, Patricelli, Matthew P, Kozarich, John W, Nomanbhoy, Tyzoon, Rosenblum, Jonathan S

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Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1[alpha] by Chemical Proteomics von Okerberg, Eric S, Hainley, Anna, Brown, Heidi, Aban, Arwin, Alemayehu, Senait, Shih, Ann, Wu, Jane, Patricelli, Matthew P, Kozarich, John W, Nomanbhoy, Tyzoon, Rosenblum, Jonathan S

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Abstract B23: Chemoproteomic profiling of native kinases during the treatment of cells with kinase inhibitors von Nomanbhoy, Tyzoon K., Brown, Heidi E., Wu, Jiangyue, Vogeti, Subha, Aban, Arwin, Grant, Wendy, Senait, Alemayehu, Wu, Shuzhen, Dias, Christa, Sharma, Geeta

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ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement von Nordin, Brian E, Liu, Yongsheng, Aban, Arwin, Brown, Heidi E, Wu, Jiangyue, Hainley, Anna K, Rosenblum, Jonathan S, Nomanbhoy, Tyzoon K, Kozarich, John W

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Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors von Li, Bei, Cociorva, Oana M., Nomanbhoy, Tyzoon, Weissig, Helge, Li, Qiang, Nakamura, Kai, Liyanage, Marek, Zhang, Melissa C., Shih, Ann Y., Aban, Arwin, Hu, Yi, Cajica, Julia, Pham, Lan, Kozarich, John W., Shreder, Kevin R.

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Synthesis and structure–activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β von Cociorva, Oana M., Li, Bei, Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Ayako, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Seto, Shigeki, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C., Aban, Arwin, Leen, Brandon, Szardenings, Anna Katrin, Rosenblum, Jonathan S., Kozarich, John W., Kohno, Yasushi, Shreder, Kevin R.

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6-Position optimization of tricyclic 4-quinolone-based inhibitors of glycogen synthase kinase-3β: Discovery of nitrile derivatives with picomolar potency von Li, Bei, Cociorva, Oana M., Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C., Aban, Arwin, Szardenings, Anna Katrin, Kozarich, John W., Kohno, Yasushi, Shreder, Kevin R.

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Profiling Native Kinases by Immuno‐Assisted Activity‐Based Profiling von Okerberg, Eric, Shih, Ann, Brown, Heidi, Alemayehu, Senait, Aban, Arwin, Nomanbhoy, Tyzoon K.

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Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3[beta] von Cociorva, Oana M, Li, Bei, Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Ayako, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Seto, Shigeki, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C, Aban, Arwin, Leen, Brandon, Szardenings, Anna Katrin, Rosenblum, Jonathan S, Kozarich, John W, Kohno, Yasushi, Shreder, Kevin R

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Inhibitor Focusing: Direct Selection of Drug Targets from Proteomes Using Activity-Based Probes von Nomanbhoy, Tyzoon K., Rosenblum, Jonathan, Aban, Arwin, Burbaum, Jonathan J.

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Inhibitor focusing: direct selection of drug targets from proteomes using activity-based probes von Nomanbhoy, Tyzoon K, Rosenblum, Jonathan, Aban, Arwin, Burbaum, Jonathan J

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