The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions von Bolouri, Hamid, Farrar, Jason E, Triche, Timothy, Ries, Rhonda E, Lim, Emilia L, Alonzo, Todd A, Ma, Yussanne, Moore, Richard, Mungall, Andrew J, Marra, Marco A, Zhang, Jinghui, Ma, Xiaotu, Liu, Yu, Liu, Yanling, Guidry Auvil, Jaime M., Davidsen, Tanja M, Gesuwan, Patee, Hermida, Leandro C, Salhia, Bodour, Capone, Stephen, Ramsingh, Giridharan, Zwaan, Christian Michel, Noort, Sanne, Piccolo, Stephen R, Kolb, E Anders, Gamis, Alan S, Smith, Malcolm A, Gerhard, Daniela S, Meshinchi, Soheil

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Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse von Farrar, Jason E, Schuback, Heather L, Ries, Rhonda E, Wai, Daniel, Hampton, Oliver A, Trevino, Lisa R, Alonzo, Todd A, Guidry Auvil, Jaime M, Davidsen, Tanja M, Gesuwan, Patee, Hermida, Leandro, Muzny, Donna M, Dewal, Ninad, Rustagi, Navin, Lewis, Lora R, Gamis, Alan S, Wheeler, David A, Smith, Malcolm A, Gerhard, Daniela S, Meshinchi, Soheil

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The genetic basis and cell of origin of mixed phenotype acute leukaemia von Alexander, Thomas B., Gu, Zhaohui, Iacobucci, Ilaria, Dickerson, Kirsten, Choi, John K., Xu, Beisi, Payne-Turner, Debbie, Yoshihara, Hiroki, Loh, Mignon L., Horan, John, Buldini, Barbara, Basso, Giuseppe, Elitzur, Sarah, de Haas, Valerie, Zwaan, C. Michel, Yeoh, Allen, Reinhardt, Dirk, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Lammens, Tim, De Moerloose, Barbara, Catchpoole, Daniel, Hori, Hiroki, Moorman, Anthony, Moore, Andrew S., Hrusak, Ondrej, Meshinchi, Soheil, Orgel, Etan, Devidas, Meenakshi, Borowitz, Michael, Wood, Brent, Heerema, Nyla A., Carrol, Andrew, Yang, Yung-Li, Smith, Malcolm A., Davidsen, Tanja M., Hermida, Leandro C., Gesuwan, Patee, Marra, Marco A., Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Jones, Steven J. M., Valentine, Marcus, Janke, Laura J., Rubnitz, Jeffrey E., Pui, Ching-Hon, Ding, Liang, Liu, Yu, Zhang, Jinghui, Nichols, Kim E., Downing, James R., Cao, Xueyuan, Shi, Lei, Pounds, Stanley, Newman, Scott, Pei, Deqing, Guidry Auvil, Jaime M., Gerhard, Daniela S., Hunger, Stephen P., Inaba, Hiroto, Mullighan, Charles G.

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A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor von Gadd, Samantha, Huff, Vicki, Walz, Amy L, Ooms, Ariadne H A G, Armstrong, Amy E, Gerhard, Daniela S, Smith, Malcolm A, Auvil, Jaime M Guidry, Meerzaman, Daoud, Chen, Qing-Rong, Hsu, Chih Hao, Yan, Chunhua, Nguyen, Cu, Hu, Ying, Hermida, Leandro C, Davidsen, Tanja, Gesuwan, Patee, Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J, Moore, Richard A, Marra, Marco A, Dome, Jeffrey S, Mullighan, Charles G, Ma, Jing, Wheeler, David A, Hampton, Oliver A, Ross, Nicole, Gastier-Foster, Julie M, Arold, Stefan T, Perlman, Elizabeth J

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The genetic landscape of high-risk neuroblastoma von Pugh, Trevor J, Morozova, Olena, Attiyeh, Edward F, Asgharzadeh, Shahab, Wei, Jun S, Auclair, Daniel, Carter, Scott L, Cibulskis, Kristian, Hanna, Megan, Kiezun, Adam, Kim, Jaegil, Lawrence, Michael S, Lichenstein, Lee, McKenna, Aaron, Pedamallu, Chandra Sekhar, Ramos, Alex H, Shefler, Erica, Sivachenko, Andrey, Sougnez, Carrie, Stewart, Chip, Ally, Adrian, Birol, Inanc, Chiu, Readman, Corbett, Richard D, Hirst, Martin, Jackman, Shaun D, Kamoh, Baljit, Khodabakshi, Alireza Hadj, Krzywinski, Martin, Lo, Allan, Moore, Richard A, Mungall, Karen L, Qian, Jenny, Tam, Angela, Thiessen, Nina, Zhao, Yongjun, Cole, Kristina A, Diamond, Maura, Diskin, Sharon J, Mosse, Yael P, Wood, Andrew C, Ji, Lingyun, Sposto, Richard, Badgett, Thomas, London, Wendy B, Moyer, Yvonne, Gastier-Foster, Julie M, Smith, Malcolm A, Auvil, Jaime M Guidry, Gerhard, Daniela S, Hogarty, Michael D, Jones, Steven J M, Lander, Eric S, Gabriel, Stacey B, Getz, Gad, Seeger, Robert C, Khan, Javed, Marra, Marco A, Meyerson, Matthew, Maris, John M

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Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia von Ma, Xiaotu, Edmonson, Michael, Yergeau, Donald, Muzny, Donna M., Hampton, Oliver A., Rusch, Michael, Song, Guangchun, Easton, John, Harvey, Richard C., Wheeler, David A., Ma, Jing, Doddapaneni, HarshaVardhan, Vadodaria, Bhavin, Wu, Gang, Nagahawatte, Panduka, Carroll, William L., Chen, I-Ming, Gastier-Foster, Julie M., Relling, Mary V., Smith, Malcolm A., Devidas, Meenakshi, Auvil, Jaime M. Guidry, Downing, James R., Loh, Mignon L., Willman, Cheryl L., Gerhard, Daniela S., Mullighan, Charles G., Hunger, Stephen P., Zhang, Jinghui

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Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism von Oldridge, Derek A., Wood, Andrew C., Weichert-Leahey, Nina, Crimmins, Ian, Sussman, Robyn, Winter, Cynthia, McDaniel, Lee D., Diamond, Maura, Hart, Lori S., Zhu, Shizhen, Durbin, Adam D., Abraham, Brian J., Anders, Lars, Tian, Lifeng, Zhang, Shile, Wei, Jun S., Khan, Javed, Bramlett, Kelli, Rahman, Nazneen, Capasso, Mario, Iolascon, Achille, Gerhard, Daniela S., Guidry Auvil, Jaime M., Young, Richard A., Hakonarson, Hakon, Diskin, Sharon J., Thomas Look, A., Maris, John M.

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Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours von Ma, Xiaotu, Liu, Yu, Liu, Yanling, Alexandrov, Ludmil B., Edmonson, Michael N., Gawad, Charles, Zhou, Xin, Li, Yongjin, Rusch, Michael C., Easton, John, Huether, Robert, Gonzalez-Pena, Veronica, Wilkinson, Mark R., Hermida, Leandro C., Davis, Sean, Sioson, Edgar, Pounds, Stanley, Cao, Xueyuan, Ries, Rhonda E., Wang, Zhaoming, Chen, Xiang, Dong, Li, Diskin, Sharon J., Smith, Malcolm A., Guidry Auvil, Jaime M., Meltzer, Paul S., Lau, Ching C., Perlman, Elizabeth J., Maris, John M., Meshinchi, Soheil, Hunger, Stephen P., Gerhard, Daniela S., Zhang, Jinghui

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Shooting the moon: the National Cancer Institute’s implementation framework for data sharing policies von Boja, Emily S., Guidry Auvil, Jaime M.

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The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia von Liu, Yu, Easton, John, Shao, Ying, Maciaszek, Jamie, Wang, Zhaoming, Wilkinson, Mark R, McCastlain, Kelly, Edmonson, Michael, Pounds, Stanley B, Shi, Lei, Zhou, Xin, Ma, Xiaotu, Sioson, Edgar, Li, Yongjin, Rusch, Michael, Gupta, Pankaj, Pei, Deqing, Cheng, Cheng, Smith, Malcolm A, Guidry Auvil, Jaime M., Gerhard, Daniela S, Relling, Mary V, Winick, Naomi J, Carroll, Andrew J, Heerema, Nyla A, Raetz, Elizabeth, Devidas, Meenakshi, Willman, Cheryl L, Harvey, Richard C, Carroll, William L, Dunsmore, Kimberly P, Winter, Stuart S, Wood, Brent L, Sorrentino, Brian P, Downing, James R, Loh, Mignon L, Hunger, Stephen P, Zhang, Jinghui, Mullighan, Charles G

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Design Strategies for Enhanced Hydrogen-Bond Donor Catalysts von Auvil, Tyler J., Schafer, Andrew G., Mattson, Anita E.

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Clinically Relevant Cytotoxic Immune Cell Signatures and Clonal Expansion of T-Cell Receptors in High-Risk MYCN -Not-Amplified Human Neuroblastoma von Wei, Jun S, Kuznetsov, Igor B, Zhang, Shile, Song, Young K, Asgharzadeh, Shahab, Sindiri, Sivasish, Wen, Xinyu, Patidar, Rajesh, Najaraj, Sushma, Walton, Ashley, Auvil, Jaime M Guidry, Gerhard, Daniela S, Yuksel, Aysen, Catchpoole, Daniel, Hewitt, Stephen M, Sondel, Paul M, Seeger, Robert, Maris, John M, Khan, Javed

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Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations von Eleveld, Thomas F, Oldridge, Derek A, Bernard, Virginie, Koster, Jan, Daage, Leo Colmet, Diskin, Sharon J, Schild, Linda, Bentahar, Nadia Bessoltane, Bellini, Angela, Chicard, Mathieu, Lapouble, Eve, Combaret, Valérie, Legoix-Né, Patricia, Michon, Jean, Pugh, Trevor J, Hart, Lori S, Rader, JulieAnn, Attiyeh, Edward F, Wei, Jun S, Zhang, Shile, Naranjo, Arlene, Gastier-Foster, Julie M, Hogarty, Michael D, Asgharzadeh, Shahab, Smith, Malcolm A, Guidry Auvil, Jaime M, Watkins, Thomas B K, Zwijnenburg, Danny A, Ebus, Marli E, van Sluis, Peter, Hakkert, Anne, van Wezel, Esther, van der Schoot, C Ellen, Westerhout, Ellen M, Schulte, Johannes H, Tytgat, Godelieve A, Dolman, M Emmy M, Janoueix-Lerosey, Isabelle, Gerhard, Daniela S, Caron, Huib N, Delattre, Olivier, Khan, Javed, Versteeg, Rogier, Schleiermacher, Gudrun, Molenaar, Jan J, Maris, John M

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Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia von McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A., Kolb, E. Anders, Gamis, Alan S., Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex

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MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours von Perlman, Elizabeth J., Gadd, Samantha, Arold, Stefan T., Radhakrishnan, Anand, Gerhard, Daniela S., Jennings, Lawrence, Huff, Vicki, Guidry Auvil, Jaime M., Davidsen, Tanja M., Dome, Jeffrey S., Meerzaman, Daoud, Hsu, Chih Hao, Nguyen, Cu, Anderson, James, Ma, Yussanne, Mungall, Andrew J., Moore, Richard A., Marra, Marco A., Mullighan, Charles G., Ma, Jing, Wheeler, David A., Hampton, Oliver A., Gastier-Foster, Julie M., Ross, Nicole, Smith, Malcolm A.

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CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML von Maxson, Julia E., Ries, Rhonda E., Wang, Yi-Cheng, Gerbing, Robert B., Kolb, E.Anders, Thompson, Sarah L., Guidry Auvil, Jaime M., Marra, Marco A., Ma, Yussanne, Zong, Zusheng, Mungall, Andrew J., Moore, Richard, Long, William, Gesuwan, Patee, Davidsen, Tanja M., Hermida, Leandro C., Hughes, Seamus B., Farrar, Jason E., Radich, Jerald P., Smith, Malcolm A., Gerhard, Daniela S., Gamis, Alan S., Alonzo, Todd A., Meshinchi, Soheil

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MYCN controls an alternative RNA splicing program in high-risk metastatic neuroblastoma von Zhang, Shile, Wei, Jun S, Li, Samuel Q, Badgett, Tom C, Song, Young K, Agarwal, Saurabh, Coarfa, Cristian, Tolman, Catherine, Hurd, Laura, Liao, Hongling, He, Jianbin, Wen, Xinyu, Liu, Zhihui, Thiele, Carol J, Westermann, Frank, Asgharzadeh, Shahab, Seeger, Robert C, Maris, John M, Guidry Auvil, Jamie M, Smith, Malcolm A, Kolaczyk, Eric D, Shohet, Jason, Khan, Javed

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Detection of intact amino acids with a hypervelocity ice grain impact mass spectrometer von Burke, Sally E, Auvil, Zachary A, Hanold, Karl A, Continetti, Robert E

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Germline pathogenic variants in neuroblastoma patients are enriched in BARD1 and predict worse survival von Kim, Jung, Vaksman, Zalman, Egolf, Laura E, Kaufman, Rebecca, Evans, J Perry, Conkrite, Karina L, Danesh, Arnavaz, Lopez, Gonzalo, Randall, Michael P, Dent, Maiah H, Farra, Lance M, Menghani, Neil L, Dymek, Malwina, Desai, Heena, Hausler, Ryan, Hicks, Belynda, Guidry Auvil, Jaime, Gerhard, Daniela S, Hakonarson, Hakon, Maxwell, Kara N, Cole, Kristina A, Pugh, Trevor J, Bosse, Kristopher R, Khan, Javed, Wei, Jun S, Maris, John M, Stewart, Douglas R, Diskin, Sharon J

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The genomic landscape of pediatric acute lymphoblastic leukemia von Brady, Samuel W., Roberts, Kathryn G., Gu, Zhaohui, Shi, Lei, Pounds, Stanley, Pei, Deqing, Cheng, Cheng, Dai, Yunfeng, Devidas, Meenakshi, Qu, Chunxu, Hill, Ashley N., Payne-Turner, Debbie, Ma, Xiaotu, Iacobucci, Ilaria, Baviskar, Pradyuamna, Wei, Lei, Arunachalam, Sasi, Hagiwara, Kohei, Liu, Yanling, Flasch, Diane A., Liu, Yu, Parker, Matthew, Chen, Xiaolong, Elsayed, Abdelrahman H., Pathak, Omkar, Li, Yongjin, Fan, Yiping, Michael, J. Robert, Rusch, Michael, Wilkinson, Mark R., Foy, Scott, Hedges, Dale J., Newman, Scott, Zhou, Xin, Wang, Jian, Reilly, Colleen, Sioson, Edgar, Rice, Stephen V., Pastor Loyola, Victor, Wu, Gang, Rampersaud, Evadnie, Reshmi, Shalini C., Gastier-Foster, Julie, Guidry Auvil, Jaime M., Gesuwan, Patee, Smith, Malcolm A., Winick, Naomi, Carroll, Andrew J., Heerema, Nyla A., Harvey, Richard C., Willman, Cheryl L., Larsen, Eric, Raetz, Elizabeth A., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Zweidler-McKay, Patrick A., Rabin, Karen R., Mattano, Leonard A., Maloney, Kelly W., Winter, Stuart S., Burke, Michael J., Salzer, Wanda, Dunsmore, Kimberly P., Angiolillo, Anne L., Crews, Kristine R., Downing, James R., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Yang, Jun J., Relling, Mary V., Gerhard, Daniela S., Loh, Mignon L., Hunger, Stephen P., Zhang, Jinghui, Mullighan, Charles G.

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