The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases von Ben Haim, Lucile, Ceyzériat, Kelly, Carrillo-de Sauvage, Maria Angeles, Aubry, Fabien, Auregan, Gwennaëlle, Guillermier, Martine, Ruiz, Marta, Petit, Fanny, Houitte, Diane, Faivre, Emilie, Vandesquille, Matthias, Aron-Badin, Romina, Dhenain, Marc, Déglon, Nicole, Hantraye, Philippe, Brouillet, Emmanuel, Bonvento, Gilles, Escartin, Carole

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Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease von NASCIMENTO-FERREIRA, Isabel, SANTOS-FERREIRA, Tiago, PEREIRA DE ALMEIDA, Luís, SOUSA-FERREIRA, Lígia, AUREGAN, Gwennaëlle, ONOFRE, Isabel, ALVES, Sandro, DUFOUR, Noëlle, COLOMER GOULD, Veronica F, KOEPPEN, Arnulf, DEGLON, Nicole

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Allele-specific silencing of mutant huntingtin in rodent brain and human stem cells von Drouet, Valérie, Ruiz, Marta, Zala, Diana, Feyeux, Maxime, Auregan, Gwennaëlle, Cambon, Karine, Troquier, Laetitia, Carpentier, Johann, Aubert, Sophie, Merienne, Nicolas, Bourgois-Rocha, Fany, Hassig, Raymonde, Rey, Maria, Dufour, Noëlle, Saudou, Frédéric, Perrier, Anselme L, Hantraye, Philippe, Déglon, Nicole

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Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease von Alves, Sandro, Nascimento-Ferreira, Isabel, Auregan, Gwennaëlle, Hassig, Raymonde, Dufour, Noëlle, Brouillet, Emmanuel, Pedroso de Lima, Maria C, Hantraye, Philippe, Pereira de Almeida, Luís, Déglon, Nicole

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Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3? von Alves, Sandro, Nascimento-Ferreira, Isabel, Dufour, Noëlle, Hassig, Raymonde, Auregan, Gwennaëlle, Nóbrega, Clévio, Brouillet, Emmanuel, Hantraye, Philippe, Pedroso de Lima, Maria C., Déglon, Nicole, de Almeida, Luís Pereira

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Ectosomes: a new mechanism for non-exosomal secretion of tau protein von Dujardin, Simon, Bégard, Séverine, Caillierez, Raphaëlle, Lachaud, Cédrick, Delattre, Lucie, Carrier, Sébastien, Loyens, Anne, Galas, Marie-Christine, Bousset, Luc, Melki, Ronald, Aurégan, Gwennaëlle, Hantraye, Philippe, Brouillet, Emmanuel, Buée, Luc, Colin, Morvane

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THY-Tau22 mouse model accumulates more tauopathy at late stage of the disease in response to microglia deactivation through TREM2 deficiency von Vautheny, Audrey, Duwat, Charlotte, Aurégan, Gwennaëlle, Joséphine, Charlène, Hérard, Anne-Sophie, Jan, Caroline, Mitja, Julien, Gipchtein, Pauline, Gaillard, Marie-Claude, Buée, Luc, Blum, David, Hantraye, Philippe, Bonvento, Gilles, Brouillet, Emmanuel, Cambon, Karine, Bemelmans, Alexis-Pierre

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Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology von Duwat, Charlotte, Léal, Pauline, Vautheny, Audrey, Aurégan, Gwennaëlle, Joséphine, Charlène, Gaillard, Marie-Claude, Hérard, Anne-Sophie, Jan, Caroline, Gipchtein, Pauline, Mitja, Julien, Fouquet, Stéphane, Niepon, Marie-Laure, Hantraye, Philippe, Brouillet, Emmanuel, Bonvento, Gilles, Cambon, Karine, Bemelmans, Alexis-Pierre

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Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies von Dujardin, Simon, Lécolle, Katia, Caillierez, Raphaëlle, Bégard, Séverine, Zommer, Nadège, Lachaud, Cédrick, Carrier, Sébastien, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Colin, Morvane, Buée, Luc

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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway von Abjean, Laurene, Ben Haim, Lucile, Riquelme-Perez, Miriam, Gipchtein, Pauline, Derbois, Céline, Palomares, Marie-Ange, Petit, Fanny, Hérard, Anne-Sophie, Gaillard, Marie-Claude, Guillermier, Martine, Gaudin-Guérif, Mylène, Aurégan, Gwennaëlle, Sagar, Nisrine, Héry, Cameron, Dufour, Noëlle, Robil, Noémie, Kabani, Mehdi, Melki, Ronald, De la Grange, Pierre, Bemelmans, Alexis P, Bonvento, Gilles, Deleuze, Jean-François, Hantraye, Philippe, Flament, Julien, Bonnet, Eric, Brohard, Solène, Olaso, Robert, Brouillet, Emmanuel, Carrillo-de Sauvage, Maria-Angeles, Escartin, Carole

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Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression von Escartin, Carole, Won, Seok Joon, Malgorn, Carole, Auregan, Gwennaelle, Berman, Ari E, Chen, Pei-Chun, Déglon, Nicole, Johnson, Jeffrey A, Suh, Sang Won, Swanson, Raymond A

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Engineered lentiviral vector targeting astrocytes In vivo von Colin, Angélique, Faideau, Mathilde, Dufour, Noelle, Auregan, Gwennaelle, Hassig, Raymonde, Andrieu, Thibault, Brouillet, Emmanuel, Hantraye, Philippe, Bonvento, Gilles, Déglon, Nicole

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The Neuroprotective Agent CNTF Decreases Neuronal Metabolites in the Rat Striatum: An in Vivo Multimodal Magnetic Resonance Imaging Study von Sauvage, Maria-Angeles Carrillo-de, Flament, Julien, Bramoulle, Yann, Haim, Lucile Ben, Guillermier, Martine, Berniard, Aurélie, Aurégan, Gwennaëlle, Houitte, Diane, Brouillet, Emmanuel, Bonvento, Gilles, Hantraye, Philippe, Valette, Julien, Escartin, Carole

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Lentiviral Delivery of the Human Wild-type Tau Protein Mediates a Slow and Progressive Neurodegenerative Tau Pathology in the Rat Brain von Caillierez, Raphaëlle, Bégard, Séverine, Lécolle, Katia, Deramecourt, Vincent, Zommer, Nadège, Dujardin, Simon, Loyens, Anne, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Buée, Luc, Colin, Morvane

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects von Faideau, Mathilde, Kim, Jinho, Cormier, Kerry, Gilmore, Richard, Welch, Mackenzie, Auregan, Gwennaelle, Dufour, Noelle, Guillermier, Martine, Brouillet, Emmanuel, Hantraye, Philippe, Déglon, Nicole, Ferrante, Robert J., Bonvento, Gilles

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Sustained effects of nonallele-specific Huntingtin silencing von Drouet, Valérie, Perrin, Valérie, Hassig, Raymonde, Dufour, Noëlle, Auregan, Gwennaelle, Alves, Sandro, Bonvento, Gilles, Brouillet, Emmanuel, Luthi-Carter, Ruth, Hantraye, Philippe, Déglon, Nicole

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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway von Abjean, Laurene, Haim, Lucile Ben, Riquelme-Perez, Miriam, Gipchtein, Pauline, Derbois, Céline, Palomares, Marie-Ange, Petit, Fanny, Hérard, Anne-Sophie, Gaillard, Marie-Claude, Guillermier, Martine, Gaudin-Guérif, Mylène, Aurégan, Gwennaëlle, Sagar, Nisrine, Héry, Cameron, Dufour, Noëlle, Robil, Noémie, Kabani, Mehdi, Melki, Ronald, De La Grange, Pierre, Bemelmans, Alexis P, Bonvento, Gilles, Deleuze, Jean-François, Hantraye, Philippe, Flament, Julien, Bonnet, Eric, Brohard, Solène, Olaso, Robert, Brouillet, Emmanuel, Carrillo-de Sauvage, Maria-Angeles, Escartin, Carole

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Lentiviral Delivery of the Human Wild-type Tau Protein Mediates a Slow and Progressive Neurodegenerative Tau Pathology in the Rat Brain von Caillierez, Raphaelle, Begard, Severine, Lecolle, Katia, Deramecourt, Vincent, Zommer, Nadege, Dujardin, Simon, Loyens, Anne, Dufour, Noelle, Auregan, Gwennaelle, Winderickx, Joris, Hantraye, Philippe, Deglon, Nicole, Buee, Luc, Colin, Morvane

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Restricted Transgene Expression in the Brain with Cell-Type Specific Neuronal Promoters von DELZOR, Aurélie, DUFOUR, Noelle, PETIT, Fanny, GUILLERMIER, Martine, HOUITTE, Diane, AUREGAN, Gwennaelle, BROUILLET, Emmanuel, HANTRAYE, Philippe, DEGLON, Nicole

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Restricted transgene expression in the brain with cell-type specific neuronal promoters von Delzor, Aurélie, Dufour, Noelle, Petit, Fanny, Guillermier, Martine, Houitte, Diane, Auregan, Gwennaelle, Brouillet, Emmanuel, Hantraye, Philippe, Déglon, Nicole

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