In Silico Mapping of Complex Disease-Related Traits in Mice von Grupe, Andrew, Germer, Soren, Usuka, Jonathan, Aud, Dee, Belknap, John K., Klein, Robert F., Ahluwalia, Mandeep K., Higuchi, Russell, Peltz, Gary

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Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma von Karp, Christopher L., Grupe, Andrew, Schadt, Eric, Ewart, Susan L., Keane-Moore, Michelle, Cuomo, Peter J., Köhl, Jörg, Wahl, Larry, Kuperman, Douglas, Germer, Soren, Aud, Dee, Peltz, Gary, Wills-Karp, Marsha

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Targeting CD157 in AML using a novel, Fc-engineered antibody construct von Krupka, Christina, Lichtenegger, Felix S., Köhnke, Thomas, Bögeholz, Jan, Bücklein, Veit, Roiss, Michael, Altmann, Torben, Do, To Uyen, Dusek, Rachel, Wilson, Keith, Bisht, Arnima, Terrett, Jon, Aud, Dee, Pombo-Villar, Esteban, Rohlff, Christian, Hiddemann, Wolfgang, Subklewe, Marion

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Genetic Mapping in Mice Identifies DMBT1 as a Candidate Modifier of Mammary Tumors and Breast Cancer Risk von Blackburn, Anneke C, Hill, Linda Z, Roberts, Amy L, Wang, Jun, Aud, Dee, Jung, Jimmy, Nikolcheva, Tania, Allard, John, Peltz, Gary, Otis, Christopher N, Cao, Qing J, Ricketts, Reva St. J, Naber, Stephen P, Mollenhauer, Jan, Poustka, Annemarie, Malamud, Daniel, Jerry, D. Joseph

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A Polymorphism in the TCF7 Gene, C883A, Is Associated With Type 1 Diabetes von NOBLE, Janelle A, WHITE, Amy M, LAZZERONI, Laura C, VALDES, Ana M, MIREL, Daniel B, REYNOLDS, Rebecca, GRUPE, Andrew, AUD, Dee, PELTZ, Gary, ERLICH, Henry A

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MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors von Merlino, Giuseppe, Fiascarelli, Alessio, Bigioni, Mario, Bressan, Alessandro, Carrisi, Corrado, Bellarosa, Daniela, Salerno, Massimiliano, Bugianesi, Rossana, Manno, Rosanna, Bernadó Morales, Cristina, Arribas, Joaquin, Dusek, Rachel L, Ackroyd, James E, Pham, Phuoc Huy, Awdew, Rahel, Aud, Dee, Trang, Michael, Lynch, Carmel M, Terrett, Jonathan, Wilson, Keith E, Rohlff, Christian, Manzini, Stefano, Pellacani, Andrea, Binaschi, Monica

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Abstract 753: The use of proteomics to analyse whole tumors and identify unique stroma cell targets for antibody-based therapeutics von Ackroyd, James, Allen, Jason, Berry, Jo, Roesch, Lisa, Barnes, Martin, Bisht, Arnima, Rohlff, Christian, Wilson, Keith, Aud, Dee, Boyd, Robert

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The Transcription Factor GATA-3 Regulates IL-4 Responses in B cells von Aud, Dee, Research Scientist, Roche Palo Alto, Palo Alto, CA, Pai, Sung-Yun, Instructor, Dana Farber Cancer Institute, Boston, MA, Peng, Stanford, Director, Arthritis Research, Roche Palo Alto, Palo Alto, CA, Ho, I-Cheng, Associate Professor, Brigham and Women's Hospital, Boston, MA

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Abstract 1321: The use of proteomics to analyze whole tumors and identify unique immuno-oncology targets for antibody-based therapeutics von Ackroyd, Jim, Bisht, Arnima, Allen, Jason, Hudson, Lindsey, Barnes, Martin, Rohlff, Christian, Wilson, Keith, Boyd, Robert, Aud, Dee

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Abstract 3646: Characterization of the novel antibody drug conjugate MEN1309 and its target antigen Ly75 von Bressan, Alessandro, Fiascarelli, Alessio, Merlino, Giuseppe, Carrisi, Corrado, Bellarosa, Daniela, Dusek, Rachel, Awdew, Rahel, Swaminathan, Sudha, Bisht, Arnima, Do, To Uyen T., Lou, San Lin, Aud, Dee, Terrett, Jonathan, Wilson, Keith, Rohlff, Christian, Binaschi, Monica

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MEN1112, a Novel Humanized De-Fucosylated Monoclonal Antibody with High Affinity and Specificity for Bst1/CD157 Antigen and Enhanced CD16 Binding von Aud, Dee, Dusek, Rachel, Bisht, Arnima, Swaminithan, Sudha, Awdew, Rahel, Trang, Michael, Lin Lou, San, Manzini, Stefano, Martinez Mogarra, Alfredo, Bressan, Alessandro, Terrett, Jon, Binaschi, Monica

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Targeting AML Using an Fc-Engineered BST1/CD157 Monoclonal Antibody von Krupka, Christina, Jansen, Anna, Lassmann, Irène, Terrett, Jon, Aud, Dee, Dusek, Rachel, Bisht, Arnima, Pombo-Villar, Esteban, Rohlff, Christian, Köhnke, Thomas, Lichtenegger, Felix S, Altmann, Torben, Metzeler, Klaus H, Fiegl, Michael, Spiekermann, Karsten, Hiddemann, Wolfgang, Subklewe, Marion

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Abstract 661: Proteomics and selecting the right combination of target and toxin for antibody-drug-conjugate (ADC) development von Terrett, Jonathan A., Dusek, Rachel, Aud, Dee, Awdew, Rahel, Swaminathan, Sudha, Lou, San Lin, Trang, Michael, Bisht, Arnima, Do, Mary, Ackroyd, Jim, Boyd, Robert, Hudson, Lindsey, Pham, Phuoc, Attanasio, Nickolas, Antani, Ami, Lynch, Carmel, Rohlff, Christian

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Targeting CD157 in AML using a novel, Fc-engineered antibody construct von Krupka, Christina, Lichtenegger, Felix S, Köhnke, Thomas, Bögeholz, Jan, Bücklein, Veit, Roiss, Michael, Altmann, Torben, Do, To Uyen, Dusek, Rachel, Wilson, Keith, Bisht, Arnima, Terrett, Jon, Aud, Dee, Pombo-Villar, Esteban, Rohlff, Christian, Hiddemann, Wolfgang, Subklewe, Marion

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Mechanisms of Disease: transcription factors in inflammatory arthritis von Aud, Dee, Peng, Stanford L

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Abstract 3869: Proteomics highlights which G-protein coupled receptors are candidates for ADC development von Kast, Juergen, Boyd, Robert, Ackroyd, James, Allen, Jason, Anderson, Amanda, Barnes, Martin, Bozhenok, Ludmila, Dusanjh, Palminder, Hudson, Lindsey, Yu, Xiaohong, Aud, Dee, Awdew, Rahel, Bisht, Arnima, Pandya, Deepal, Trang, Michael, Terrett, Jonathan, Rohlff, Christian

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Abstract 1683: High throughput membrane proteomics for the discovery of oncology targets ideally suited for the development of antibody drug conjugates (ADCs) von Terrett, Jonathan A., Bozhenok, Ludmila, Belanger, Blake, Montes, Inigo, Aud, Dee, Ackroyd, Jim, Anderson, Amanda, Trang, Michael, Barnes, Martin, Lamble, Harry, Yu, Xiaohong, Rohlff, Christian

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Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members von Patel, Anand C, Morton, Jeffrey D, Kim, Edy Y, Alevy, Yael, Swanson, Suzanne, Tucker, Jennifer, Huang, Guaming, Agapov, Eugene, Phillips, Thomas E, Fuentes, Maria E, Iglesias, Antonio, Aud, Dee, Allard, John D, Dabbagh, Karim, Peltz, Gary, Holtzman, Michael J

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Interleukin-6 is required for a protective immune response to systemic Escherichia coli infection von DALRYMPLE, S. A, SLATTERY, R, AUD, D. M, KRISHNA, M, LUCIAN, L. A, MURRAY, R

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Mice deficient for the IL-3/GM-CSF/IL-5 βc receptor exhibit lung pathology and impaired immune response, while βIL3 receptor-deficient mice are normal von Nishinakamura, Ryuichi, Nakayama, Naoki, Hirabayashi, Yoko, Inoue, Tohru, Aud, Dee, Mcneil, Tom, Azuma, Sadahiro, Yoshida, Shosei, Toyoda, Yutaka, Aral, Ken-ichi, Miyajima, Atsushi, Murray, Richard

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