Discovery of novel S1P2 antagonists. Part 1: Discovery of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Kanaji, Toshiya, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Seko, Takuya

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Synthesis and evaluation of a potent, well-balanced EP 2 /EP 3 dual agonist von Kinoshita, Akihiro, Higashino, Masato, Yoshida, Koji, Aratani, Yoshiyuki, Kakuuchi, Akito, Hanada, Keisuke, Takeda, Hiroyuki, Naganawa, Atsushi, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Discovery of novel S1P2 antagonists, part 3: Improving the oral bioavailability of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Yamamoto, Hiroshi, Seko, Takuya

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Synthesis of Phototrappable Shape-Shifting Molecules for Adaptive Guest Binding von Lippert, Alexander R, Naganawa, Atsushi, Keleshian, Vasken L, Bode, Jeffrey W

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Discovery of novel S1P2 antagonists. Part 2: Improving the profile of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Ueda, Hideyuki, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Seko, Takuya

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Discovery of an 8-Aza-5-thiaProstaglandin E1 Analog as a Highly Selective EP4 Receptor Agonist von Kambe, Tohru, Maruyama, Toru, Naganawa, Atsushi, Asada, Masaki, Seki, Akiteru, Maruyama, Takayuki, Nakai, Hisao, Toda, Masaaki

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Anion‐Responsive π‐Electronic Systems Exhibiting Diverse Conformations and Stoichiometries in Anion Binding von Haketa, Yohei, Naganawa, Atsushi, Sugiura, Shinya, Yasuda, Nobuhiro, Maeda, Hiromitsu

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Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis von Ishida, Akiharu, Okabe, Yasuyuki, Matsushita, Takeshi, Sekiguchi, Tetsuya, Nishio, Takuya, Komagata, Tatsuya, Iwaki, Masanori, Miyata, Hidenori, Katagi, Jun, Naganawa, Atsushi, Maruyama, Toru, Imagawa, Akira

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Synthesis and evaluation of a potent, well-balanced EP2/EP3 dual agonist von Kinoshita, Akihiro, Higashino, Masato, Yoshida, Koji, Aratani, Yoshiyuki, Kakuuchi, Akito, Hanada, Keisuke, Takeda, Hiroyuki, Naganawa, Atsushi, Matsuya, Hidekazu, Ohmoto, Kazuyuki

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Chemical sensing with shapeshifting organic molecules von Larson, Kimberly K., He, Maggie, Teichert, Johannes F., Naganawa, Atsushi, Bode, Jeffrey W.

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Design and Synthesis of a Highly Selective EP2-Receptor Agonist von Tani, Kousuke, Naganawa, Atsushi, Ishida, Akiharu, Egashira, Hiromu, Sagawa, Kenji, Harada, Hiroyuki, Ogawa, Mikio, Maruyama, Takayuki, Ohuchida, Shuichi, Nakai, Hisao, Kondo, Kigen, Toda, Masaaki

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Discovery and SAR Studies of Orally Active Somatostatin Receptor Subtype‑2 (SSTR2) Agonists for the Treatment of Acromegaly von Ishida, Akiharu, Tajima, Yohei, Okabe, Yasuyuki, Matsushita, Takeshi, Sekiguchi, Tetsuya, Imaide, Satomi, Nomura, Yoshinori, Tanaka, Motoyuki, Nojima, Shoji, Yoshida, Atsushi, Iyoda, Yoko, Aoki, Shohei, Nishio, Takuya, Komagata, Tatsuya, Iwaki, Masanori, Shono, Tomoyuki, Naganawa, Atsushi, Imagawa, Akira

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Discovery of novel S1P sub(2) antagonists, part 3: Improving the oral bioavailability of a series of 1,3-bis(aryloxy)benzene derivatives von Kusumi, Kensuke, Shinozaki, Koji, Yamaura, Yoshiyuki, Hashimoto, Ai, Kurata, Haruto, Naganawa, Atsushi, Otsuki, Kazuhiro, Matsushita, Takeshi, Sekiguchi, Tetsuya, Kakuuchi, Akito, Yamamoto, Hiroshi, Seko, Takuya

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Development of a highly selective EP2-receptor agonist. Part 1: identification of 16-hydroxy-17,17-trimethylene PGE2 derivatives von Tani, Kousuke, Naganawa, Atsushi, Ishida, Akiharu, Sagawa, Kenji, Harada, Hiroyuki, Ogawa, Mikio, Maruyama, Takayuki, Ohuchida, Shuichi, Nakai, Hisao, Kondo, Kigen, Toda, Masaaki

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Chemical sensing with shapeshifting organic moleculesElectronic supplementary information (ESI) available. See DOI: 10.1039/c2sc20238g von Larson, Kimberly K, He, Maggie, Teichert, Johannes F, Naganawa, Atsushi, Bode, Jeffrey W

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Discovery of new orally active prostaglandin D2 receptor antagonists von Iwahashi, Maki, Naganawa, Atsushi, Kinoshita, Atsushi, Shimabukuro, Atsushi, Nishiyama, Toshihiko, Ogawa, Seiji, Matsunaga, Yoko, Tsukamoto, Kohki, Okada, Yutaka, Matsumoto, Ryoji, Nambu, Fumio, Oumi, Rie, Odagaki, Yoshihiko, Katagi, Jun, Yano, Koji, Tani, Kousuke, Nakai, Hisao, Toda, Masaaki

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Discovery of new orally active prostaglandin D sub(2 receptor antagonists) von Iwahashi, Maki, Naganawa, Atsushi, Kinoshita, Atsushi, Shimabukuro, Atsushi, Nishiyama, Toshihiko, Ogawa, Seiji, Matsunaga, Yoko, Tsukamoto, Kohki, Okada, Yutaka, Matsumoto, Ryoji, Nambu, Fumio, Oumi, Rie, Odagaki, Yoshihiko, Katagi, Jun, Yano, Koji, Tani, Kousuke, Nakai, Hisao, Toda, Masaaki

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Further optimization of sulfonamide analogs as EP1 receptor antagonists: Synthesis and evaluation of bioisosteres for the carboxylic acid group von Naganawa, Atsushi, Matsui, Toshiaki, Ima, Masaki, Saito, Tetsuji, Murota, Masayuki, Aratani, Yoshiyuki, Kijima, Hideomi, Yamamoto, Hiroshi, Maruyama, Takayuki, Ohuchida, Shuichi, Nakai, Hisao, Toda, Masaaki

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Discovery of new chemical leads for selective EP1 receptor antagonists von Naganawa, Atsushi, Saito, Tetsuji, Nagao, Yuuki, Egashira, Hiromu, Iwahashi, Maki, Kambe, Tohru, Koketsu, Masatoshi, Yamamoto, Hiroshi, Kobayashi, Michiyoshi, Maruyama, Takayuki, Ohuchida, Shuichi, Nakai, Hisao, Kondo, Kigen, Toda, Masaaki

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Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists von Naganawa, Atsushi, Matsui, Toshiaki, Ima, Masaki, Yoshida, Koji, Tsuruta, Hiroshi, Yamamoto, Shingo, Yamamoto, Hiroshi, Okada, Hiroki, Maruyama, Takayuki, Nakai, Hisao, Kondo, Kigen, Toda, Masaaki

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