Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors von WALKER, Scott S, YIMING XU, NORRIS, Christine, ANTONACCI, Barry, GURNANI, Maya, CACCIAPUOTI, Anthony, MCNICHOLAS, Paul M, WAINHAUS, Samuel, JASON HERR, R, KUANG, Rongze, ASLANIAN, Robert G, TING, Pauline C, TRIANTAFYLLOU, Ilias, BLACK, Todd A, WALDMAN, Michelle F, MENDRICK, Cara, BROWN, Nathaniel, MANN, Paul, CHAU, Andrew, PATEL, Reena, BAUMAN, Nicholas

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Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors von Zhou, Gang, Ting, Pauline C., Wishart, Grant, Zorn, Nicolas, Aslanian, Robert G., Lin, Mingxiang, Smith, Michelle, Walker, Scott S., Cook, John, Van Heek, Margaret, Lachowicz, Jean

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Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity von de Lera Ruiz, Manuel, Zheng, Junying, Berlin, Michael Y., McCormick, Kevin D., Aslanian, Robert G., West, Robert, Hwa, Joyce, Lachowicz, Jean, van Heek, Margaret

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Discovery of oral and inhaled PDE4 inhibitors von Ting, Pauline C., Lee, Joe F., Kuang, Rongze, Cao, Jianhua, Gu, Danlin, Huang, Ying, Liu, Zhidan, Aslanian, Robert G., Feng, Kung-I., Prelusky, Daniel, Lamca, James, House, Aileen, Phillips, Jonathan E., Wang, Peng, Wu, Ping, Lundell, Daniel, Chapman, Richard W., Celly, Chander S.

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Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists von Zeng, Qingbei, Rosenblum, Stuart B., Yang, Zhaoxia, Jiang, Yueheng, McCormick, Kevin D., Aslanian, Robert G., Duguma, Luli, Kozlowski, Joseph A., Shih, Neng-Yang, Hey, John A., West, Robert E., Korfmacher, Walter A., Berlin, Michael, Boyce, Christopher W.

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Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl) thiazolopyridine as H3 receptor antagonists von RAO, Ashwin U, PALANI, Anandan, LACHOWICZ, Jean, XIAO CHEN, YING HUANG, ASLANIAN, Robert G, WEST, Robert E, WILLIAMS, Shirley M, WU, Ren-Long, HWA, Joyce, SONDEY, Christopher

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Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors von Ting, Pauline C., Lee, Joe F., Zorn, Nicolas, Kim, Hyunjin M., Aslanian, Robert G., Lin, Mingxiang, Smith, Michelle, Walker, Scott S., Cook, John, Van Heek, Margaret, Lachowicz, Jean

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The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitors von Ting, Pauline C., Kuang, Rongze, Wu, Heping, Aslanian, Robert G., Cao, Jianhua, Kim, David W., Lee, Joe F., Schwerdt, John, Zhou, Gang, Wainhaus, Samuel, Black, Todd A., Cacciapuoti, Anthony, McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors von Zych, Andrew J., Lam, Sang Q., Jenkins, David M., Herr, R. Jason, Ting, Pauline C., Lee, Joe F., Kuang, Rongze, Wu, Heping, Kim, David W., Aslanian, Robert G., Wainhaus, Samuel, Black, Todd A., Cacciapuoti, Anthony, McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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The optimization of pyridazinone series of glucan synthase inhibitors von Kuang, Rongze, Wu, Heping, Ting, Pauline C., Aslanian, Robert G., Cao, Jianhua, Kim, David W., Lee, Joe F., Schwerdt, John, Zhou, Gang, Jason Herr, R., Zych, Andrew J., Yang, Jinhai, Lam, Sang Q., Jenkins, David M., Sakwa, Samuel A., Wainhaus, Samuel, Black, Todd A., Cacciapuoti, Anthony, McNicholas, Paul M., Xu, Yiming, Walker, Scott S.

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Strong Antimicrobial Activity of Hydroxamic Acids and Newly Synthesized Derivatives von Antunes, Daniel Ignacio D., Aslanian, Robert G., Aqani, Omar, Desai, Harshal, Bendaoud, Meriem

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Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes von Rao, Ashwin U, Shao, Ning, Aslanian, Robert G, Chan, Tin-Yau, Degrado, Sylvia J, Wang, Li, McKittrick, Brian, Senior, Mary, West, Robert E, Williams, Shirley M, Wu, Ren-Long, Hwa, Joyce, Patel, Bhuneshwari, Zheng, Shuqin, Sondey, Christopher, Palani, Anandan

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Palladium-catalyzed Negishi α-arylation of alkylsulfones von Zhou, Gang, Ting, Pauline C., Aslanian, Robert G.

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Synthesis and structure–activity relationships of 2-(1,4′-bipiperidin-1′-yl)thiazolopyridine as H 3 receptor antagonists von Rao, Ashwin U., Palani, Anandan, Chen, Xiao, Huang, Ying, Aslanian, Robert G., West, Robert E., Williams, Shirley M., Wu, Ren-Long, Hwa, Joyce, Sondey, Christopher, Lachowicz, Jean

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Discovery of a Potent Thiadiazole Class of Histamine H 3 Receptor Antagonist for the Treatment of Diabetes von Rao, Ashwin U., Shao, Ning, Aslanian, Robert G., Chan, Tin-Yau, Degrado, Sylvia J., Wang, Li, McKittrick, Brian, Senior, Mary, West, Robert E., Williams, Shirley M., Wu, Ren-Long, Hwa, Joyce, Patel, Bhuneshwari, Zheng, Shuqin, Sondey, Christopher, Palani, Anandan

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Pharmacological Characterization of a Novel α 2C -Adrenoceptor Agonist N -[3,4-dihydro-4-(1 H -imidazol-4-ylmethyl)-2 H -1, 4-benzoxazin-6-yl]- N -ethyl- N ′-methylurea (Compound A... von Corboz, Michel R., Rivelli, Maria A., McCormick, Kevin D., Wan, Yuntao, Shah, Himanshu, Umland, Shelby, Lieber, Gisela, Jia, Yanlin, McLeod, Robbie L., Morgan, Cynthia, Varty, Geoffrey B., Wu, Jie, Feng, Kung-I, Boyce, Christopher W., Aslanian, Robert G., Palamanda, Jai, Nomeir, Amin A., Korfmacher, Walter, Hunter, John C., Anthes, John C., Hey, John A.

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Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: expedient synthesis of a 2,2-disubstituted piperidine NK1 antagonist von Xiao, Dong, Lavey, Brian J., Palani, Anandan, Wang, Cheng, Aslanian, Robert G., Kozlowski, Joseph A., Shih, Neng-Yang, McPhail, Andrew T., Randolph, Gerard P., Lachowicz, Jean E., Duffy, Ruth A.

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Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H sub(3) receptor antagonists von Rao, Ashwin U, Palani, Anandan, Chen, Xiao, Huang, Ying, Aslanian, Robert G, West, Robert E, Williams, Shirley M, Wu, Ren-Long, Sondey, Christopher, Lachowicz, Jean

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Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: expedient synthesis of a 2,2-disubstituted piperidine NK 1 antagonist von Xiao, Dong, Lavey, Brian J., Palani, Anandan, Wang, Cheng, Aslanian, Robert G., Kozlowski, Joseph A., Shih, Neng-Yang, McPhail, Andrew T., Randolph, Gerard P., Lachowicz, Jean E., Duffy, Ruth A.

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Pharmacological characterization of a novel α2C-adrenoceptor agonist N-[3,4-dihydro-4-(1H-imidazol-4-ylmethyl)-2H-1, 4-benzoxazin-6-yl]-N-ethyl-N'-methylurea (compound A) von Corboz, Michel R, Rivelli, Maria A, McCormick, Kevin D, Wan, Yuntao, Shah, Himanshu, Umland, Shelby, Lieber, Gisela, Jia, Yanlin, McLeod, Robbie L, Morgan, Cynthia, Varty, Geoffrey B, Wu, Jie, Feng, Kung-I, Boyce, Christopher W, Aslanian, Robert G, Palamanda, Jai, Nomeir, Amin A, Korfmacher, Walter, Hunter, John C, Anthes, John C, Hey, John A

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