Cardiovascular disease: The rise of the genetic risk score von Knowles, Joshua W, Ashley, Euan A

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Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments von Van Valen, David A, Kudo, Takamasa, Lane, Keara M, Macklin, Derek N, Quach, Nicolas T, DeFelice, Mialy M, Maayan, Inbal, Tanouchi, Yu, Ashley, Euan A, Covert, Markus W

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A guide for the diagnosis of rare and undiagnosed disease: beyond the exome von Marwaha, Shruti, Knowles, Joshua W, Ashley, Euan A

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Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association von O’Sullivan, Jack W., Raghavan, Sridharan, Marquez-Luna, Carla, Luzum, Jasmine A., Damrauer, Scott M., Ashley, Euan A., O’Donnell, Christopher J., Willer, Cristen J., Natarajan, Pradeep

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Towards precision medicine von Ashley, Euan A.

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Multi-task deep learning for cardiac rhythm detection in wearable devices von Torres-Soto, Jessica, Ashley, Euan A.

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Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells von Lan, Feng, Lee, Andrew S., Liang, Ping, Sanchez-Freire, Veronica, Nguyen, Patricia K., Wang, Li, Han, Leng, Yen, Michelle, Wang, Yongming, Sun, Ning, Abilez, Oscar J., Hu, Shijun, Ebert, Antje D., Navarrete, Enrique G., Simmons, Chelsey S., Wheeler, Matthew, Pruitt, Beth, Lewis, Richard, Yamaguchi, Yoshinori, Ashley, Euan A., Bers, Donald M., Robbins, Robert C., Longaker, Michael T., Wu, Joseph C.

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Deep learning interpretation of echocardiograms von Ghorbani, Amirata, Ouyang, David, Abid, Abubakar, He, Bryan, Chen, Jonathan H., Harrington, Robert A., Liang, David H., Ashley, Euan A., Zou, James Y.

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The Precision Medicine Initiative: A New National Effort von Ashley, Euan A

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Time trajectories in the transcriptomic response to exercise - a meta-analysis von Amar, David, Lindholm, Malene E., Norrbom, Jessica, Wheeler, Matthew T., Rivas, Manuel A., Ashley, Euan A.

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Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank von Tikkanen, Emmi, Gustafsson, Stefan, Amar, David, Shcherbina, Anna, Waggott, Daryl, Ashley, Euan A., Ingelsson, Erik

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A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay von Seeger, Timon, Shrestha, Rajani, Lam, Chi Keung, Chen, Caressa, McKeithan, Wesley L, Lau, Edward, Wnorowski, Alexa, McMullen, George, Greenhaw, Matthew, Lee, Jaecheol, Oikonomopoulos, Angelos, Lee, Soah, Yang, Huaxiao, Mercola, Mark, Wheeler, Matthew, Ashley, Euan A, Yang, Fan, Karakikes, Ioannis, Wu, Joseph C

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De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects von Priest, James R, Osoegawa, Kazutoyo, Mohammed, Nebil, Nanda, Vivek, Kundu, Ramendra, Schultz, Kathleen, Lammer, Edward J, Girirajan, Santhosh, Scheetz, Todd, Waggott, Daryl, Haddad, Francois, Reddy, Sushma, Bernstein, Daniel, Burns, Trudy, Steimle, Jeffrey D, Yang, Xinan H, Moskowitz, Ivan P, Hurles, Matthew, Lifton, Richard P, Nickerson, Debbie, Bamshad, Michael, Eichler, Evan E, Mital, Seema, Sheffield, Val, Quertermous, Thomas, Gelb, Bruce D, Portman, Michael, Ashley, Euan A

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Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study von DeBoever, Christopher, Tanigawa, Yosuke, Lindholm, Malene E., McInnes, Greg, Lavertu, Adam, Ingelsson, Erik, Chang, Chris, Ashley, Euan A., Bustamante, Carlos D., Daly, Mark J., Rivas, Manuel A.

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Clinical Interpretation and Implications of Whole-Genome Sequencing von Dewey, Frederick E, Grove, Megan E, Pan, Cuiping, Goldstein, Benjamin A, Bernstein, Jonathan A, Chaib, Hassan, Merker, Jason D, Goldfeder, Rachel L, Enns, Gregory M, David, Sean P, Pakdaman, Neda, Ormond, Kelly E, Caleshu, Colleen, Kingham, Kerry, Klein, Teri E, Whirl-Carrillo, Michelle, Sakamoto, Kenneth, Wheeler, Matthew T, Butte, Atul J, Ford, James M, Boxer, Linda, Ioannidis, John P. A, Yeung, Alan C, Altman, Russ B, Assimes, Themistocles L, Snyder, Michael, Ashley, Euan A, Quertermous, Thomas

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Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks von Amar, David, Sinnott-Armstrong, Nasa, Ashley, Euan A., Rivas, Manuel A.

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Challenges in the clinical application of whole-genome sequencing von Ormond, Kelly E, MSc, Wheeler, Matthew T, MD, Hudgins, Louanne, Prof, Klein, Teri E, PhD, Butte, Atul J, MD, Altman, Russ B, Prof, Ashley, Euan A, MRCP, Greely, Henry T, Prof

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Performance comparison of whole-genome sequencing platforms von Lam, Hugo Y K, Clark, Michael J, Chen, Rui, Chen, Rong, Natsoulis, Georges, O'Huallachain, Maeve, Dewey, Frederick E, Habegger, Lukas, Ashley, Euan A, Gerstein, Mark B, Butte, Atul J, Ji, Hanlee P, Snyder, Michael

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Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis von Goldfeder, Rachel L, Wall, Dennis P, Khoury, Muin J, Ioannidis, John P A, Ashley, Euan A

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Benchmarking workflows to assess performance and suitability of germline variant calling pipelines in clinical diagnostic assays von Krishnan, Vandhana, Utiramerur, Sowmithri, Ng, Zena, Datta, Somalee, Snyder, Michael P., Ashley, Euan A.

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